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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Improved methods for capture of circulating tumor cells could help in disease tracking

Tumor cells circulating throughout the body in blood vessels have long been feared as harbingers of metastasizing cancer - even though most free-floating cancer cells will not go on to establish a new tumor.

15 Mar 2018

The Importance of Fetal Fibronectin Testing for Women with Symptomatic Preterm Labor

Preterm birth is a dangerous condition that often goes undiagnosed. Fetal fibronectin (fFN) is a biomarker for preterm labor, but testing for fFN is widely underused. We explore this issue with Dr. Michael S. Ruma, a maternal-fetal specialist from the Perinatal Associates of New Mexico.

14 Mar 2018

Southern Research scientists target mutated protein to combat prostate cancer

Southern Research scientists are exploring how a mutated protein implicated in prostate cancer plays a role in the development of the disease and whether it holds a key to better treatment outcomes.

13 Mar 2018

Study validates Xpresys Lung 2 for differential diagnosis of early stage lung cancer

Integrated Diagnostics today announced the e-publication of full results of a large prospective clinical trial validating its Xpresys Lung 2 in the peer-reviewed medical journal CHEST¸ the official journal of the American College of Chest Physicians, titled: Assessment of Plasma Proteomics Biomarker’s Ability to Distinguish Benign From Malignant Lung Nodules: Results of the PANOPTIC trial.

12 Mar 2018

Researchers show role for predictive biomarker in neonatal chronic lung disease pathogenesis

Extremely low birth-weight babies are at risk for a chronic lung disease called bronchopulmonary dysplasia, or BPD.

9 Mar 2018

New version of troponin test can detect heart attack within one hour

When Marc Hammer went to the emergency room feeling fatigued and dizzy, he had no idea his life was actually at risk. "I'm an avid cyclist and walk five to 15 miles a day," said Hammer, "so you can imagine my shock when I found out I was facing a heart issue. It came out of the blue."

8 Mar 2018

MRI-based models can help reduce unnecessary biopsies in suspected prostate cancer patients

In a collaborative, multi-institutional study published by JAMA Oncology, researchers from the University of Alabama at Birmingham, University of Chicago, and National Cancer Institute determined that MRI-based prediction models can help reduce unnecessary biopsies in suspected prostate cancer patients and help improve personalized risk stratification.

7 Mar 2018

Oracle Health Sciences study explores status of precision medicine initiatives and challenges

Oracle Health Sciences today announced the results of a new study that explores the current and planned status of precision medicine initiatives, associated challenges and the future impact of this discipline on life sciences and healthcare communities.

7 Mar 2018

Levels of inflammatory biomarkers could predict effectiveness of ECT for people with depression

People with major depression that has not been well controlled by medications and who have a biomarker in their blood indicating a higher level of inflammation may benefit more than people with less inflammation from electroconvulsive therapy to ease symptoms of their depression, according to a new UCLA study.

6 Mar 2018

New PET imaging agent allows early detection of prostate cancer relapse

An Italian study featured in the March issue of The Journal of Nuclear Medicine demonstrates that a novel nuclear medicine imaging agent targeting copper accumulation in tumors can detect prostate cancer recurrence early in patients with biochemical relapse (rising prostate-specific antigen [PSA] level).

5 Mar 2018

$Heart failure patients with preserved ejection fraction have better survival outcomes, study shows$

Heart failure patients with preserved ejection fraction have better survival outcomes, study shows

A joint 7-year cohort study of 2039 patients in both Singapore's restructured hospitals and New Zealand's hospitals, revealed answers to key questions about the epidemiology of heart failure.

2 Mar 2018

New sample storage technique could lead to better health care in resource-limited regions

Blood and urine tests play vital roles in modern medicine. Yet in vast regions of the world where refrigeration is not available, preserving samples for testing is virtually impossible.

28 Feb 2018

Study shows importance of family history in onset of Alzheimer's disease

You're about to turn 60, and you're fretting. Your mother has had Alzheimer's disease since the age of 65. At what age will the disease strike you? A Canadian study published in JAMA Neurology shows that the closer a person gets to the age at which their parent exhibited the first signs of Alzheimer's, the more likely they are to have amyloid plaques, the cause of the cognitive decline associated with the disease, in their brain.

27 Feb 2018

Researchers develop first analytical method to evaluate new cyanide and mustard gas antidote

To develop antidotes for chemical agents, such as cyanide and mustard gas, scientists need analytical methods that track not only the level of exposure but also how the drug counteracts the effects of the chemical.

24 Feb 2018

Study finds tobacco smoke exposure among most adolescents in economically disadvantaged population

Ninety-four percent of adolescents ages 13 to 19 in an economically disadvantaged, largely minority population in San Francisco had measurable levels of a biomarker specific for exposure to tobacco smoke.

23 Feb 2018

Study sheds light on biological mechanisms that drive rare pediatric neurogenetic disorders

Researchers studying a rare genetic disorder that causes severe, progressive neurological problems in childhood have discovered insights into biological mechanisms that drive the disease, along with early clues that an amino acid supplement might offer a targeted therapy.

22 Feb 2018

3D Signatures reports positive results of new Telo-HL test for Hodgkin's lymphoma

3D Signatures Inc. is pleased to announce that a preliminary third-party analysis of the trial data for Telo-HL, 3DS' test in development for Hodgkin's lymphoma (HL), shows that the Company's TeloViewTM platform is able to distinguish, with a high degree of statistical significance, multiple differences between a patient group that responds to standard ABVD chemotherapy, and a group that relapses or is refractory to treatment within the first 12 months.

22 Feb 2018

New study identifies novel molecular biomarkers of preeclampsia

Preeclampsia, a sudden pregnancy complication that can interfere with the blood flow to the placenta and possibly to the fetus, can lead to low birth weight, prematurity and even death.

22 Feb 2018

Study employs novel approach to uncover new biomarker for CHD

Coronary heart disease (CHD) is the number one cause of death in both men and women. While many risk factors of CHD, such as smoking, high blood pressure and age, are common among men and women, some metabolic risk factors, such as being diabetic, are more strongly associated with increased risk of CHD in women than in men.

21 Feb 2018

Zika virus could be alternative for treatment of aggressive brain cancer

Zika virus, feared for causing microcephaly in babies whose mothers were infected during pregnancy by attacking the cells that will give rise to the fetus's cerebral cortex, could be an alternative for treatment of glioblastoma, the most common and aggressive kind of malignant brain tumor in adults.

21 Feb 2018

Biomarker News and Research

Further Reading

Improved methods for capture of circulating tumor cells could help in disease tracking

The Importance of Fetal Fibronectin Testing for Women with Symptomatic Preterm Labor

Southern Research scientists target mutated protein to combat prostate cancer

Study validates Xpresys Lung 2 for differential diagnosis of early stage lung cancer

Researchers show role for predictive biomarker in neonatal chronic lung disease pathogenesis

New version of troponin test can detect heart attack within one hour

MRI-based models can help reduce unnecessary biopsies in suspected prostate cancer patients

Oracle Health Sciences study explores status of precision medicine initiatives and challenges

Levels of inflammatory biomarkers could predict effectiveness of ECT for people with depression

New PET imaging agent allows early detection of prostate cancer relapse

Heart failure patients with preserved ejection fraction have better survival outcomes, study shows

New sample storage technique could lead to better health care in resource-limited regions

Study shows importance of family history in onset of Alzheimer's disease

Researchers develop first analytical method to evaluate new cyanide and mustard gas antidote

Study finds tobacco smoke exposure among most adolescents in economically disadvantaged population

Study sheds light on biological mechanisms that drive rare pediatric neurogenetic disorders

3D Signatures reports positive results of new Telo-HL test for Hodgkin's lymphoma

New study identifies novel molecular biomarkers of preeclampsia

Study employs novel approach to uncover new biomarker for CHD

Zika virus could be alternative for treatment of aggressive brain cancer

Event guide: World Clinical Biomarkers & CDx Summit Japan eBook

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