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New study implicates role of HDAC9 gene in calcification of the human aorta

Arterial wall calcification is the buildup of calcium in the blood vessel walls, which can often be a predictor of serious cardiovascular events like heart attacks and strokes. Scientists have long pointed to family history as one possible cause for this hardening of the arteries, but a new study published in Nature Genetics implicates a specific gene - HDAC9 - in the calcification of the human aorta, the largest blood vessel in the body.

29 Oct 2019

Creighton University researcher wins NIH grant to study osteoporosis in diabetic women

From a corner office high atop CHI Health Immanuel, a longtime Creighton University researcher is plotting another step along a road he hopes will eventually free diabetic women from osteoporosis, one of many diseases that strike diabetics more forcefully than the general population.

29 Oct 2019

Dynamic molecular signaling waves control embryonic fates

Timing is everything for young cells waiting to determine their identities.

29 Oct 2019

Cancer drug may delay progression of bone and other myeloma-related organ damage

The largest randomized trial in asymptomatic patients with smoldering multiple myeloma suggests that lenalidomide, a cancer drug, may delay the onset of bone and other myeloma-related organ damage.

28 Oct 2019

Society for Maternal-Fetal Medicine releases statement in response to PROLONG trial results

The Society for Maternal-Fetal released the following statement in response to the published results of "Progestin's Role in Optimizing Neonatal Gestation," more commonly referred to as the PROLONG trial, which was recently published in the American Journal of Perinatology.

25 Oct 2019

Phase 2 clinical trial of CAR T-cell therapy starts at Atlantic Health System

Atlantic Health System is treating patients in a new Phase 2 clinical trial of CAR T-cell therapy at Morristown Medical Center. A select number of sites across the U.S. are involved in this study, which is done on an outpatient basis.

25 Oct 2019

Metabolite profiling during diagnosis helps identify poor treatment outcomes in ALL

The survival of patients with pediatric acute lymphoblastic leukemia (ALL) has significantly improved in the last several decades. However, novel strategies to identify cases that are likely to respond poorly to treatment are still needed.

24 Oct 2019

UA Little Rock receives $5.6 million DOD grant to advance bone regeneration technology

The U.S. Department of Defense has awarded the University of Arkansas at Little Rock a $5.6 million grant to advance the NuCress scaffold, a groundbreaking bone regeneration technology.

24 Oct 2019

Direct current stimulation device aids in spinal fusion procedure

Spine surgeons in the U.S. perform more than 400,000 spinal fusions each year as a way to ease back pain and prevent vertebrae in the spine from wiggling around and doing more damage.

24 Oct 2019

Cleveland Clinic announces Top 10 Medical Innovations for 2020

A dual-acting osteoporosis drug. Minimally invasive mitral valve surgery. New treatment for peanut allergies. These are some of the innovations that will enhance healing and change healthcare in the coming year, according to a distinguished panel of doctors and researchers.

23 Oct 2019

An elbow can be used to estimate the sex of skeletons

An elbow can help determine the sex of a skeleton. In an effort to help identify skeletal remains of Thai descent, researchers from Boston University School of Medicine have found that examining the distal humerus (elbow) bone is superior to previous techniques that were developed for identifying sex in a non-Asian population.

23 Oct 2019

Northwestern Medicine launches program to help women understand risk factors for osteoporosis

Loss of bone density is common as women age, particularly around menopause when women lose more bone than they make. When bone density becomes so low that fracture is likely, the condition is called osteoporosis.

23 Oct 2019

Hong Kong Baptist University receives FDA orphan drug designation for novel aptamer

A research team from the School of Chinese Medicine at Hong Kong Baptist University has successfully developed a novel aptamer, i.e. a single-stranded piece of DNA, for the treatment of osteogenesis imperfecta (OI) with the aid of artificial intelligence (AI) technology.

23 Oct 2019

Vitamin D deficiency linked to poor muscle strength in older adults

New research from Trinity College Dublin shows that vitamin D deficiency is an important determinant of poor skeletal muscle function in adults aged 60 years and over.

23 Oct 2019

Anti-arthritis drug can stop tuberculosis bacillus from infecting blood stem cells

Immunologist Johan Van Weyenbergh (KU Leuven) and his Belgian-Brazilian colleagues have shown that a drug used to fight arthritis also stops the process that allows the tuberculosis bacillus to infect and hijack blood stem cells.

23 Oct 2019

Researchers uncover earlier origin of the neural crest in chick embryos

Neural crest cells -- embryonic cells in vertebrates that travel throughout the body and generate many cell types -- have been thought to originate in the ectoderm, the outermost of the three germ layers formed in the earliest stages of embryonic development.

22 Oct 2019

Bone News and Research

New study implicates role of HDAC9 gene in calcification of the human aorta

Creighton University researcher wins NIH grant to study osteoporosis in diabetic women

Dynamic molecular signaling waves control embryonic fates

Cancer drug may delay progression of bone and other myeloma-related organ damage

Society for Maternal-Fetal Medicine releases statement in response to PROLONG trial results

Phase 2 clinical trial of CAR T-cell therapy starts at Atlantic Health System

Metabolite profiling during diagnosis helps identify poor treatment outcomes in ALL

UA Little Rock receives $5.6 million DOD grant to advance bone regeneration technology

Direct current stimulation device aids in spinal fusion procedure

Cleveland Clinic announces Top 10 Medical Innovations for 2020

An elbow can be used to estimate the sex of skeletons

Northwestern Medicine launches program to help women understand risk factors for osteoporosis

Hong Kong Baptist University receives FDA orphan drug designation for novel aptamer

Vitamin D deficiency linked to poor muscle strength in older adults

Anti-arthritis drug can stop tuberculosis bacillus from infecting blood stem cells

Researchers uncover earlier origin of the neural crest in chick embryos

IOF Compendium highlights urgent need to maintain mobility in older populations

Cold plasma jets as promising tool for minimally invasive cancer therapy

Study to examine whether cancer and co-occurring Alzheimer's alter pain perception

GlobalData highlights low diagnosis and treatment rates of osteoporosis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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