Fibrosis News and Research

RSS

Fibrosis is the growth of fibrous tissue.

Discovery of possible target for prevention and treatment of pneumonia

Researchers at Children's Hospital of Pittsburgh of UPMC have identified a key protein target that may be a crucial factor in the development of a vaccine to prevent and new therapies to treat pneumonia, the leading killer of children worldwide.

12 Feb 2008

Bone problems and cystic fibrosis

A recent study by Dr Christina Haston, a researcher of the McGill University Health Centre research Institute, sheds some new light on the bone problems that generally accompany cystic fibrosis.

8 Feb 2008

Chemical chaperone could open door to treatment of neurological disorder

An unexpected finding turned out to be a clue leading researchers at Washington University School of Medicine in St. Louis to propose a new treatment approach for Niemann-Pick disease, a rare, deadly neurodegenerative disorder.

7 Feb 2008

Experimental drug shows promise for cystic fibrosis

An experimental drug that has proven effective in treating muscular dystrophy also works for cystic fibrosis, according to researchers at the University of Alabama at Birmingham (UAB).

5 Feb 2008

Study of successful drug targets could hasten development of new medications

Guidance from an innovative computational approach could speed up the process and cut down the cost of new drug development, researchers from the University of Chicago Medical Center and Columbia University suggest in a study to be published in the February 2008 issue of Genome Research, available early online.

5 Feb 2008

Two new studies examine non-invasive ways to determine liver fibrosis and cirrhosis

An enhanced version of the Original European Liver Fibrosis panel was found to have good diagnostic accuracy for fibrosis in patients with non-alcoholic fatty liver disease. Conversely, transient elastography was unreliable for detecting cirrhosis in patients with acute liver damage. The studies are published in the February issue of Hepatology, a journal by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). The articles are also available online at Wiley Interscience.

5 Feb 2008

Enzyme released by mast cells in the lungs could be a new target for asthma

An enzyme released by mast cells in the lungs appears to play a key role in the tightening of airways that is a hallmark of asthma pointing to a potential new target for treatment against the illness.

4 Feb 2008

New understanding of ion channel regulation

A study at Rush University Medical Center in Chicago published this week in the online version of Biophysical Journal proposes that bubbles may control the opening and closing of ion channels.

4 Feb 2008

Exposure to secondhand smoke linked to worsening of lung function in cystic fibrosis sufferers

Exposure to secondhand smoke is associated with adverse effects on lung function among persons with cystic fibrosis, with this effect being worse for persons with certain gene variations, according to a study in the January 30 issue of JAMA.

31 Jan 2008

Lungs' mast cells could provide new treatment target for asthma, other respiratory disease

30 Jan 2008

New target found for asthma

An enzyme released by mast cells in the lungs appears to play a key role in the tightening of airways that is a hallmark of asthma -- pointing to a potential new target for treatment against the illness.

29 Jan 2008

Adult stem cell application effective in treatment of peripheric vascular disease

Multipotent adult progenitor stem cells extracted from bone marrow, and known as MAPCs, have proved to be effective in the regeneration of blood vessel tissue and also in muscle tissue when treating peripheric vascular disease.

25 Jan 2008

Myostatin inhibitors may make injuries more likely

Block the action of a protein that normally regulates muscle mass, and watch your muscles grow.

23 Jan 2008

Debate over safety of gene therapy trials focuses on issue of informed consent

Can a patient who agrees to participate in a safety study of a gene therapy protocol give truly informed consent and understand the risks involved when the consent forms are highly technical and the physician or institution seeking their consent has a stake in the study and its outcome?

23 Jan 2008

New research finds way for wounds to heal without scars

The researchers from Bristol University believe their discovery has major implications not just for wound victims, but also for people who suffer organ tissue damage through illness or abdominal surgery.

22 Jan 2008

Minute genetic differences have major consequences

A study led by McGill University researchers has demonstrated that small differences between individuals at the DNA level can lead to dramatic differences in the way genes produce proteins.

21 Jan 2008

Case researcher in RNA biology makes waves by challenging current thinking

In the January 18th issue of Molecular Cell, Case Western Reserve University School of Medicine researcher Kristian E. Baker, Ph.D. challenges molecular biology's established body of evidence and widely-accepted model for nonsense-mediated messenger ribonucleic acid (mRNA) decay.

21 Jan 2008