Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Spatial orgnization of the genome can be altered using small molecules

Researchers have discovered that the spatial organization of the genome can be altered using small molecule compounds which are considered as promising anti-cancer drugs.

16 Apr 2019

Restoring function of 'misregulated' cancer-fighting genes

Working with human colon cancer cells and mice, researchers led by experts at the Johns Hopkins Kimmel Cancer Center say they have successfully blocked the activity of portions of a protein known as UHRF1 and restored the function of hundreds of cancer-fighting genes that became "misregulated" by the disease.

15 Apr 2019

Key gene could decrease detrimental brain swelling after stroke

Could a medication someday help the brain heal itself after a stroke, or even prevent damage following a blow to the head? A new USC study lends support to the idea.

15 Apr 2019

Unisex, hormone-free contraceptive pill on the horizon

Side effects from hormonal contraceptives are common. That’s why one start-up is developing a hormone-free contraceptive that can be used by both men and women.

12 Apr 2019

Active lifestyle shown to repair spinal cord injuries

Leading an active lifestyle could help repair and regenerate damaged nerves of the spinal cord after an injury, according to new research.

12 Apr 2019

Scientists develop new approach to unravel toxic effects of multiple stressors

Genomic markers are the key in a new approach for assessing the toxic effects arising from exposure to multiple stressors.

11 Apr 2019

Researchers discover pathway contributing to fatty liver disease

Researchers from Karolinska Institutet have found a protein that is a critical regulator in the development of fatty liver disease in mice, according to a study published in the journal Nature Communications.

11 Apr 2019

Active lifestyle influences regenerative capacity of neurons after spinal cord injury

The influence of an active lifestyle on the regenerative capacity of the peripheral nervous system, that is, the set of cranial and spinal nerves that control motor and sensory functions, is described here for the first time, explains Ángel Barco, who has led the participation of the Institute of Neurosciences UMH-CSIC, in Alicante, in this international study.

11 Apr 2019

Researchers find presence of Aire gene in lymph nodes

The thymus is the organ in which T cells differentiate. T cells express various T cell receptors for reacting with various pathogenic microbes and viruses.

11 Apr 2019

Active lifestyles may help damaged nerves to regenerate after spinal cord injury

Leading an active lifestyle may increase the likelihood of damaged nerves regenerating after a spinal cord injury.

10 Apr 2019

Newly developed approach efficiently assesses carcinogenicity of chemicals

Researchers from Boston University Schools of Medicine and Public Health have developed and evaluated a fast, accurate and cost-effective approach to assessing the carcinogenicity of chemicals--that is, whether exposure to a chemical increases a person's long-term cancer risk.

10 Apr 2019

Single-cell sequencing sheds light on landscape of myeloid cells in lung tumors

The recent emergence of immunotherapy has marked a sea change in research and care for many forms of cancer, bringing new hope to patients and families around the world. For those who respond to treatment, the results can be dramatic.

10 Apr 2019

Study reveals how higher educational attainment may stave off cognitive decline

Prefrontal brain regions linked to higher educational attainment are characterized by increased expression of genes involved in neurotransmission and immunity, finds a study of healthy older adults published in JNeurosci.

From Society for Neuroscience 9 Apr 2019

Study of pregnant women with lupus identifies early indicators of pregnancy complications

A study of pregnant women with systemic lupus erythematosus has identified early changes in the RNA molecules present in the blood that could be used to determine the likelihood of them developing preeclampsia.

8 Apr 2019

A gene regulatory multi-tool plays key role in unjamming the genome after DNA damage

A protein complex that is involved in nearly every step in the regulatory control of gene expression in cells has now been shown also to play a key role in clearing potential traffic jams in the production of RNA.

5 Apr 2019

NYU biologists develop methods to validate gene regulatory networks

A team of biologists and computer scientists has mapped out a network of interactions for how plant genes coordinate their response to nitrogen, a crucial nutrient and the main component of fertilizer.

5 Apr 2019

New hope for treating devastating brain cancer in children

There could be new treatments on the horizon for diffuse intrinsic pontine glioma, or DIPG, a devastating form of brain cancer that afflicts young children and is currently incurable.

5 Apr 2019

Research unravels possible factor for female bias in lupus

The autoimmune disease lupus, which can cause fatigue, a facial rash, and joint pain, strikes females far more often than males. Eight-five percent of people with lupus are female, and their second X chromosome seems partly to blame.

5 Apr 2019

Poverty can become embedded across wide swaths of the genome, study finds

A new Northwestern University study challenges prevailing understandings of genes as immutable features of biology that are fixed at conception.

4 Apr 2019

Study evaluates effects of unpaired 1 gene overexpression on lifespan in flies

Alexey Moskalev, Ph.D., Head of the Laboratory of Geroprotective and Radioprotective technologies, and co-authors from the Institute of biology of Komi Science Center of RAS announce the publication of a scientific article titled "Effects of unpaired 1 gene overexpression on the lifespan of Drosophila melanogaster" in BMC Systems Biology - an open access journal publishing original peer-reviewed research articles in experimental and theoretical aspects of the function of biological systems at the molecular, cellular or organismal level.

4 Apr 2019