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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

First placebo-controlled clinical study results of BYETTA injection with Lantus presented at ADA 2010

Amylin Pharmaceuticals, Inc. and Eli Lilly and Company today announced results from the first double-blind, placebo-controlled clinical study to evaluate BYETTA (exenatide) injection added to Lantus (insulin glargine), which showed patients with type 2 diabetes achieved glucose targets without weight gain or increasing their risk of hypoglycemia. These findings were presented at the 70th Annual Scientific Sessions of the American Diabetes Association in Orlando, Fla.

28 Jun 2010

Oxygen' common stock to begin trading on Swiss SIX Exchange

Oxygen Biotherapeutics, Inc. announced today that the company's common stock will begin trading on the Swiss SIX Exchange with the opening of trading tomorrow, Tuesday, June 29, 2010. The company's shares will trade under the same ticker symbol, OXBT, as they currently do on the NASDAQ Capital Market.

28 Jun 2010

New research finds key proteins involved in the process of memory and learning

New research led by the University of Leicester and published in a prestigious international scientific journal has revealed for the first time the mechanism by which memories are formed.

28 Jun 2010

Raptor initiates enrollment in pivotal Phase 3 clinical trial of DR Cysteamine for nephropathic cystinosis

Raptor Pharmaceutical Corp. announced that it has enrolled the first patient in a pivotal Phase 3 clinical trial of its proprietary delayed-release oral formulation of cysteamine bitartrate ("DR Cysteamine") in patients with nephropathic cystinosis ("cystinosis").

28 Jun 2010

EMA CHMP recommends marketing approval of BRINAVESS for conversion of recent onset AF to sinus rhythm

Merck and Cardiome Pharma Corp. today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has recommended marketing approval for BRINAVESS® (vernakalant), an investigational intravenous (IV) formulation for the conversion of recent onset atrial fibrillation (AF) to sinus rhythm in adults.

28 Jun 2010

Arena's lorcaserin reduces body weight across patient subgroups

Arena Pharmaceuticals, Inc. today reported pooled Week 52 data from more than 6,000 patients in lorcaserin's pivotal Phase 3 clinical trial program that demonstrate lorcaserin 10 mg dosed twice daily reduced body weight in all patient subgroups evaluated, as defined by gender, age, ethnicity and starting body weight and Body Mass Index (BMI). Greater improvements in cardiovascular risk factors were also achieved with lorcaserin treatment compared to placebo overall and in most subgroups.

28 Jun 2010

New center opens for vets with traumatic brain injuries and psychological issues

"The $65 million medical center, which opened Thursday, is devoted exclusively to helping members of the military who suffer from traumatic brain injuries, PTSD and other psychological issues. Its opening comes on the heels of a flurry of congressional criticism and reports claiming that soldiers with traumatic brain injuries often do not have their conditions diagnosed and are forced to wade through the vast bureaucracy of the Defense Centers of Excellence for Psychological Help and Traumatic Brain Injury, which is charged with their treatment."

28 Jun 2010

Antioxidant therapy may prevent long-lasting cognitive impairment in cerebral malaria: Research

Using an experimental mouse model for malaria, an international group of scientists has discovered that adding antioxidant therapy to traditional antimalarial treatment may prevent long-lasting cognitive impairment in cerebral malaria. Their findings were published online June 24, 2010, in the journal PLoS Pathogens.

28 Jun 2010

Data on MetAP2 inhibitors for treatment of obesity presented at ADA 2010

Zafgen, Inc., a pharmaceutical company pioneering novel obesity therapeutics to help the body regain and sustain a lean, healthy state by targeting imbalances in fat metabolism, today announced data on ZGN-201, a prototype methionine aminopeptidase 2 inhibitor, for the treatment of obesity. Preclinical studies demonstrate MetAP2 inhibition eliminates excess body weight through the regulation of fat metabolism and food intake, and normalizes glucose tolerance in animal models.

28 Jun 2010

National Intrepid Center of Excellence to treat veterans with traumatic brain injury

The U.S. Department of Defense and the Intrepid Fallen Heroes Fund on June 24 officially dedicated the National Intrepid Center of Excellence, a new 72,000-square-foot medical facility in Bethesda, Md., dedicated to researching, diagnosing and treating traumatic brain injury in U.S. military personnel.

28 Jun 2010

New findings could lead to simple dietary solutions, possible therapeutics for gestational diabetes

The cause of diabetes during pregnancy is directly controlled by serotonin, a chemical produced by the body and normally known as a neurotransmitter, and is influenced by the amount of protein in the mother's diet early in pregnancy, according to new findings of an international team led by researchers at UCSF.

28 Jun 2010

ARS study finds link between vitamin D and cognitive function

At a time when consumer interest in health-enhancing foods is high, Agricultural Research Service (ARS)-funded scientists have contributed to a limited but growing body of evidence of a link between vitamin D and cognitive function.

25 Jun 2010

Athersys, CSCRM and CWRU receive $1M to advance MultiStem therapy for SCI

Athersys, Inc. and its collaborators, including the Center for Stem Cell and Regenerative Medicine and Case Western Reserve University, announced today that they have been awarded $1 million through the Ohio Third Frontier Biomedical Program to support research into the treatment of spinal cord injury with MultiStem, Athersys' proprietary stem cell product candidate.

25 Jun 2010

Neuralstem signs definitive agreements to sell $10M of units in registered-direct offering

Neuralstem, Inc. announced today that it has entered into definitive agreements to sell $10 million of units at $2.80 per unit in a registered-direct offering to institutional investors. The units consist of: (i) one share of common stock, and (ii) 3/4 common stock purchase warrant. The warrants have an exercise price of $3.25 and a term of three years.

25 Jun 2010

Scientists discover characteristic amyloid plaques in retinas from Alzheimer's disease patients

The nerve cell-damaging plaque that builds up in the brain with Alzheimer's disease also builds up in the retinas of the eyes - and it shows up there earlier, leading to the prospect that noninvasive optical imaging of the eyes could lead to earlier diagnosis, intervention and monitoring of the disease, according to new research.

25 Jun 2010

CHMP adopts positive opinion on pending MAA for SYCREST sublingual tablets

Merck announced that the Committee for Medicinal Products for Human Use adopted a positive opinion on the pending Marketing Authorization Application for SYCREST (asenapine) sublingual tablets. The CHMP has recommended that the European Commission grant a marketing authorization for SYCREST for the treatment of moderate to severe manic episodes associated with bipolar I disorder in adults. The CHMP did not support an indication for the treatment of schizophrenia.

25 Jun 2010

First Edition: June 25, 2010

Today's headlines reflect the latest news about the House passing a temporary ban on cuts in Medicare reimbursements to doctors, while Senate Democrats failed to gain approval for their jobs bill, which included enhanced Medicaid aid to states.

25 Jun 2010

Research findings suggest possible diagnostic test for ALS

A team led by a Los Angeles Biomedical Research Institute researcher developed a novel approach to efficiently identify disease relevant genes in human complex neurological disorders and demonstrated the effectiveness of this method by applying it to Amyotrophic Lateral Sclerosis, or Lou Gehrig's Disease, according to a new study reported online in the journal, Human Molecular Genetics.

25 Jun 2010

Scientist at Children Hospital Los Angeles receives NIH grant to research on meningitis

A white blood cell that normally removes bacteria from the bloodstream helps Escherichia coli (E. coli) accumulate in the blood and enter the brain resulting in the deadly infection known as meningitis. Prasadarao V. Nemani, PhD, a scientist at The Saban Research Institute at Children Hospital Los Angeles plans to find out how this happens with a grant of $1.65 million from the National Institutes of Health - National Institute of Neurological Disorders and Strokes.

25 Jun 2010

Neurosurgeons applaud newly-released draft standards for supervision, duty hours of medical residents

The American Association of Neurological Surgeons, American Board of Neurological Surgery, Congress of Neurological Surgeons, and Society of Neurological Surgeons applaud the newly-released draft standards to revise the national requirements for the supervision and duty hours of medical residents.

25 Jun 2010

Brain News and Research

Further Reading

First placebo-controlled clinical study results of BYETTA injection with Lantus presented at ADA 2010

Oxygen' common stock to begin trading on Swiss SIX Exchange

New research finds key proteins involved in the process of memory and learning

Raptor initiates enrollment in pivotal Phase 3 clinical trial of DR Cysteamine for nephropathic cystinosis

EMA CHMP recommends marketing approval of BRINAVESS for conversion of recent onset AF to sinus rhythm

Arena's lorcaserin reduces body weight across patient subgroups

New center opens for vets with traumatic brain injuries and psychological issues

Antioxidant therapy may prevent long-lasting cognitive impairment in cerebral malaria: Research

Data on MetAP2 inhibitors for treatment of obesity presented at ADA 2010

National Intrepid Center of Excellence to treat veterans with traumatic brain injury

New findings could lead to simple dietary solutions, possible therapeutics for gestational diabetes

ARS study finds link between vitamin D and cognitive function

Athersys, CSCRM and CWRU receive $1M to advance MultiStem therapy for SCI

Neuralstem signs definitive agreements to sell $10M of units in registered-direct offering

Scientists discover characteristic amyloid plaques in retinas from Alzheimer's disease patients

CHMP adopts positive opinion on pending MAA for SYCREST sublingual tablets

First Edition: June 25, 2010

Research findings suggest possible diagnostic test for ALS

Scientist at Children Hospital Los Angeles receives NIH grant to research on meningitis

Neurosurgeons applaud newly-released draft standards for supervision, duty hours of medical residents

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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