Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Study reveals the link between low fitness and increased waist circumference

A new study published in the open-access journal PLOS ONE, identified an inverse correlation between low fitness and large waist size as well as a higher degree of inflammation.

18 Jan 2018

Study suggests movement as accurate method to diagnose neurodevelopmental disorders

A new study led by researchers at Indiana University and Rutgers University provides the strongest evidence yet that nearly imperceptible changes in how people move can be used to diagnose neurodevelopmental disorders, including autism.

18 Jan 2018

Research: Men who lack HSD17B4 gene may be more susceptible to treatment-resistant prostate cancer

Cleveland Clinic researchers have confirmed for the first time a mechanistic link between the gene HSD17B4 and deadly, treatment-resistant prostate cancer.

17 Jan 2018

Humanitarian program decreases stress hormone levels in adolescents affected by war

A new study shows that a humanitarian program to improve the mental health of adolescents affected by the Syrian war has decreased levels of cortisol (a hormone associated with stress) in participants by a third.

12 Jan 2018

Insilico Medicine develops new deep-learning based hematological human aging clock

Today, Insilico Medicine, Inc., a Baltimore-based company specializing in the application of artificial intelligence for drug discovery, biomarker development and aging research, announced a publication of a research paper titled "Population-specific biomarkers of human aging: a big data study using South Korean, Canadian and Eastern-European patient populations" in The Journal of Gerontology.

11 Jan 2018

Researchers discover new promising biomarker for colorectal cancer

Researchers from the University of Luxembourg found a new biomarker for colorectal cancer (CRC) that might improve therapy and survival rates of patients.

11 Jan 2018

Clinical study investigates lifestyle biomarkers in prostate cancer survivors

Advanced glycation end products, which have been linked to many chronic diseases, including diabetes, cardiovascular disease and cancer, build up in the body from birth due to normal metabolism but are often higher in those eating the high-fat, high-sugar, highly processed foods characteristic of the Western diet.

11 Jan 2018

New discovery could help treat breast cancer through precision medicine

University of Alberta researchers have discovered a mechanism that may make cancer cells more susceptible to treatment. The research team found that the protein RYBP prevents DNA repair in cancer cells, including breast cancer.

9 Jan 2018

New blood stabilization method prolongs lifespan of blood samples for CTC profiling

A new blood stabilization method, developed at the Massachusetts General Hospital Center for Engineering in Medicine, significantly prolongs the lifespan of blood samples for microfluidic sorting and transcriptome profiling of rare circulating tumor cells (CTCs), living cancer cells carried in the bloodstream.

9 Jan 2018

Adrenomedullin could serve as biomarker, therapeutic target in disorders caused by leaky blood vessels

Disorders caused by a leaky vasculature are more common than most people think. Despite ICU treatment, one third of the 27 million patients globally that suffer from sepsis, and up to 20% of the more than 5 million US patients with congestive heart failure die every year from their condition.

5 Jan 2018

Researchers use Quest MRI to identify earliest signs of Alzheimer's disease in mice

Alzheimer's disease wreaks emotional havoc on patients, who are robbed of their memories, their dignity, and their lives. It's financially devastating as well: care for Alzheimer's patients is predicted to top $1 trillion by about the time children born today are having children of their own.

5 Jan 2018

Wake Forest Baptist receives NIH grant for alcohol addiction research center

The National Institutes of Health has awarded Wake Forest Baptist Medical Center a grant worth an estimated $8 million over five years for the establishment of a new center for research into alcohol addiction.

3 Jan 2018

New total-body PET scanner could revolutionize patient diagnosis and care

The new total-body PET/CT scanner could revolutionize our understanding and treatment of disease through analysis of better imaging data from the whole body.

3 Jan 2018

Discovery of potential biomarker for Huntington's disease may help postpone disease onset

A new discovery of a potential biomarker for Huntington's disease (HD) could mean a more effective way of evaluating the effectiveness of treatments for this neurological disease.

2 Jan 2018

IQWiG experts contradict MINDACT study data on biomarker tests for breast cancer

The American Society of Clinical Oncology recently updated its guideline on biomarkers with regard to the MammaPrint test and published this update in the Journal of Clinical Oncology.

27 Dec 2017

Study identifies biomarker targets to make existing drugs better at combating cancer

A new study published in Nature Communications and led by University of Kentucky Markey Cancer Center researcher Qing-Bai She identifies biomarker targets that may make existing drugs more effective in fighting certain cancers.

22 Dec 2017

Sahlgrenska University Hospital becomes first Swedish site to take part in early pancreatic cancer detection study

Immunovia AB today announced that Sahlgrenska University Hospital is the first Swedish site to be part of PanFAM-1, a multicenter prospective validation study for the early diagnosis in familiar pancreatic cancer (FPC) high risk individuals.

22 Dec 2017

Tumor growth traits can influence response to cancer drugs, study finds

Individual tumors respond differently to cancer drugs, if at all. Until now, it remained a mystery why tumors have different reactions to the exact same therapy. But a new study at the USC Viterbi School of Engineering finds that tumor growth properties can influence response to cancer drugs.

21 Dec 2017

New system makes it easier to detect rare molecules linked to early disease

By attaching specialized molecules to the backbone of DNA, researchers have made it easier to detect rare molecules associated with early disease.

20 Dec 2017

Scientists develop test to predict treatment outcomes in patients with childhood leukemia

UC San Francisco physician-scientists have developed a test that can predict how patients with juvenile myelomonocytic leukemia (JMML) will respond to treatment, and may also be able to identify patients who are likely to recover spontaneously with little to no treatment.

19 Dec 2017

Biomarker News and Research

Further Reading

Study reveals the link between low fitness and increased waist circumference

Study suggests movement as accurate method to diagnose neurodevelopmental disorders

Research: Men who lack HSD17B4 gene may be more susceptible to treatment-resistant prostate cancer

Humanitarian program decreases stress hormone levels in adolescents affected by war

Insilico Medicine develops new deep-learning based hematological human aging clock

Researchers discover new promising biomarker for colorectal cancer

Clinical study investigates lifestyle biomarkers in prostate cancer survivors

New discovery could help treat breast cancer through precision medicine

New blood stabilization method prolongs lifespan of blood samples for CTC profiling

Adrenomedullin could serve as biomarker, therapeutic target in disorders caused by leaky blood vessels

Researchers use Quest MRI to identify earliest signs of Alzheimer's disease in mice

Wake Forest Baptist receives NIH grant for alcohol addiction research center

New total-body PET scanner could revolutionize patient diagnosis and care

Discovery of potential biomarker for Huntington's disease may help postpone disease onset

IQWiG experts contradict MINDACT study data on biomarker tests for breast cancer

Study identifies biomarker targets to make existing drugs better at combating cancer

Sahlgrenska University Hospital becomes first Swedish site to take part in early pancreatic cancer detection study

Tumor growth traits can influence response to cancer drugs, study finds

New system makes it easier to detect rare molecules linked to early disease

Scientists develop test to predict treatment outcomes in patients with childhood leukemia

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

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