Genomic News and Research

RSS

Researchers identify chemicals that keep HIV virus in dormant state

When the human immunodeficiency virus infects cells, it can either exploit the cells to start making more copies of itself or remain dormant--a phenomenon called latency.

24 Mar 2021

Researchers test novel gene regulation approach to treat brain diseases

Researchers at the DZNE (Germany), at Massachusetts General Hospital (USA) and at the genomic medicine company Sangamo Therapeutics, Inc. tested a novel gene regulation approach to treat brain diseases such as Alzheimer's in laboratory studies.

22 Mar 2021

Bacteria residing within tumor cells can boost cancer immunotherapy

Cancer immunotherapy may get a boost from an unexpected direction: bacteria residing within tumor cells.

22 Mar 2021

Joint project aims to establish automated system for SARS-CoV-2 analysis in wastewater

On March 19, 2021, Hokkaido University, Robotic Biology Institute Inc., iLAC Co., Ltd., and Shionogi & Co., Ltd. have entered into a memorandum of understanding (MOU) toward the establishment of an automated system for the analysis of the novel coronavirus (SARS-CoV-2) in wastewater.

20 Mar 2021

Underrepresentation in genomic databases may affect therapy selection for minority patients

Low representation of minority groups in public genomic databases may affect therapy selection for Black patients with cancer, according to new Mayo Clinic research published in npj Precision Oncology.

19 Mar 2021

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

A new study, released on the bioRxiv* preprint server, describes the mechanism of inflammation in severe COVID-19, besides revealing a potential new therapeutic target to modulate the severity of COVID-19.

19 Mar 2021

DNA spike-ins increase reliability of amplicon-based sequencing of SARS-CoV-2 genomes

In the interests of cost-effectiveness and rapidity, amplicon-based sequencing of the viral genome has been used to provide a sensitive means of genomic surveillance. A new preprint, which was released on the bioRxiv* server, shows how this can be tweaked to make it a reliable source of genomic data by reducing the known potential for contamination.

19 Mar 2021

New variant may not have changed COVID-19 pandemic course in UK, says study

A new study examines the effect of the new "Kent variant" of SARS-CoV-2 on the epidemic course within the UK.

19 Mar 2021

Rare pulmonary disease discovered in rural Alberta

A rare pulmonary disease that is linked to bats has made Alberta home, according to new research led by provincial lab scientists.

19 Mar 2021

Study investigates how genetic variants contribute to increased risk of lung cancer

Lung cancer is the leading cause of cancer death in the U.S. for both men and women. While risk for this disease can be influenced by environmental and lifestyle factors like smoking, studies estimate that 18% of lung cancer cases are due to inherited genetic variants.

18 Mar 2021

Landmark Covid relief law pumps more than $100 billion into public health

Acknowledging that chronic underfunding of public health contributed significantly to the nation's fragmented response to the coronavirus pandemic, Democrats included more than $100 billion in the recently enacted relief package to address urgent needs and enhance future efforts.

18 Mar 2021

Study characterizes shifting neoantigen burden between primary and metastatic tumors within HNSCC

Oncotarget published "Genomic and neoantigen evolution from primary tumor to first metastases in head and neck squamous cell carcinoma" which reported that prior work has characterized changes in the mutation burden between primary and recurrent tumors; however, little work has characterized the changes in neoantigen evolution.

18 Mar 2021

New SARS-CoV-2 variant in France appears undetectable by PCR

French authorities have announced the emergence of a new variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the northwestern region of Brittany that has escaped detection by standard polymerase chain reaction (PCR) tests.

17 Mar 2021

A complete genetic and clinical analysis of individuals with SCN2A-related disorders

Researchers from Children's Hospital of Philadelphia affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) have compiled a complete genetic and clinical analysis of more than 400 individuals with SCN2A-related disorder, which has been linked to a variety of neurodevelopmental disorders, including epilepsy and autism.

17 Mar 2021

Researchers develop innovative profiling methods for SARS-CoV-2 infection

A team of researchers from various institutions in the USA used RNA-sequencing data and other methods to profile unique genes and other characteristics associated with SARS-CoV-2 in New York City (NYC).

17 Mar 2021

Abbott Pandemic Defence Coalition aims to identify new viral threats and take quick action

Abbott today announced the formation of the Abbott Pandemic Defence Coalition, a first-of-its-kind global scientific and public health partnership dedicated to the early detection of, and rapid response to, future pandemic threats.

17 Mar 2021

UVA researcher developing innovative gene therapy to help children with Rett syndrome

A University of Virginia School of Medicine scientist is developing an innovative gene therapy she hopes will slow disease progression and improve movement, coordination and communication in children with Rett syndrome.

17 Mar 2021

Compromised immunity can allow SARS-CoV-2 to evade the immune system

The vast majority of people infected with SARS-CoV-2 clear the virus, but those with compromised immunity--such as individuals receiving immune-suppressive drugs for autoimmune diseases--can become chronically infected.

17 Mar 2021

Study could lead to the development of novel treatments for drug-resistant cancers

ETC-159, a made-in-Singapore anti-cancer drug that is currently in early phase clinical trials for use in a subset of colorectal and gynecological cancers, could also prevent some tumors from resisting therapies by blocking a key DNA repair mechanism, researchers from Duke-NUS Medical School and the Agency for Science, Technology and Research in Singapore reported in the journal EMBO Molecular Medicine.

16 Mar 2021

Ferret study shows SARS-CoV-2 airborne transmission dynamics

A team of researchers led by Sander Herfst from Erasmus University Medical Center in The Netherlands suggests severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could spread through the air at a one-meter distance and cause infection in a new ferret model study.

16 Mar 2021

Genomic News and Research

Researchers identify chemicals that keep HIV virus in dormant state

Researchers test novel gene regulation approach to treat brain diseases

Bacteria residing within tumor cells can boost cancer immunotherapy

Joint project aims to establish automated system for SARS-CoV-2 analysis in wastewater

Underrepresentation in genomic databases may affect therapy selection for minority patients

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

DNA spike-ins increase reliability of amplicon-based sequencing of SARS-CoV-2 genomes

New variant may not have changed COVID-19 pandemic course in UK, says study

Rare pulmonary disease discovered in rural Alberta

Study investigates how genetic variants contribute to increased risk of lung cancer

Landmark Covid relief law pumps more than $100 billion into public health

Study characterizes shifting neoantigen burden between primary and metastatic tumors within HNSCC

New SARS-CoV-2 variant in France appears undetectable by PCR

A complete genetic and clinical analysis of individuals with SCN2A-related disorders

Researchers develop innovative profiling methods for SARS-CoV-2 infection

Abbott Pandemic Defence Coalition aims to identify new viral threats and take quick action

UVA researcher developing innovative gene therapy to help children with Rett syndrome

Compromised immunity can allow SARS-CoV-2 to evade the immune system

Study could lead to the development of novel treatments for drug-resistant cancers

Ferret study shows SARS-CoV-2 airborne transmission dynamics

Industry focus eBook: Genomics (4th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News