Preclinical News and Research

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Innovative technology could help treat cancer more selectively and effectively

Treating cancer more selectively and more effectively - this could be achieved with an innovative technology developed by teams of researchers at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie and the Ludwig-Maximilians-Universität München.

9 Aug 2019

Longer-lived, but less toxic drug may work better for pancreatic cancer

Unlike many other cancers, most pancreatic tumors are rock hard.

9 Aug 2019

Innovative technology could treat cancer more selectively and effectively

9 Aug 2019

HistoIndex, ILBS launch Center of Excellence to enhance NASH diagnostics and clinical trials

In a cross border collaboration, HistoIndex and the Institute of Liver & Biliary Sciences (ILBS) in New Delhi, India have jointly launched a Centre of Excellence to aid diagnostics and clinical trials focusing on NASH.

8 Aug 2019

New improved model for cancer wasting syndrome cachexia

A new model of cancer-related cachexia promises to help scientists understand why patients with cancer show severe wasting, which in turn may drive the development of better therapies.

7 Aug 2019

New 3D-cardiac tissue platform can predict how heart responds to drugs

Researchers from TARA Biosystems, Inc. and GlaxoSmithKline today published data demonstrating that TARA's engineered heart-on-a-chip system replicated drug responses found in adult humans.

7 Aug 2019

New mouse model could lead to a better understanding of cachexia syndrome

A study published in Cell Reports Aug. 6 describes the generation of a new mouse model developed at Hollings Cancer Center that could lead to a better understanding of the cachexia syndrome. This wasting condition, characterized by excessive weight loss, has one of the highest incidences in pancreatic cancer patients.

6 Aug 2019

Novel medical device protects healthy organs from radiation exposure during particle therapy

Kobe University and Alfresa Pharma Corporation develop a novel medical device with non-woven fabric style made of bioabsorbable material.

5 Aug 2019

Study could open a new era in transplantation medicine

For decades, immunologists have been trying to train the transplant recipient's immune system to accept transplanted cells and organs without the long-term use of anti-rejection drugs. New University of Minnesota preclinical research shows that this is now possible.

5 Aug 2019

Combination therapy could be a promising treatment for late-stage acute lymphoblastic leukemia

Acute lymphoblastic leukemia accounts for one in five adult leukemias, and is the most common pediatric cancer in the United States.

29 Jul 2019

Study analyzes the prevalence of antipsychotic use in youths with ADHD

Although fewer young people with ADHD are treated with antipsychotic drugs than suspected, many prescriptions for the drugs do not appear to be clinically warranted, according to a new study from psychiatry researchers at Columbia University Vagelos College of Physicians and Surgeons.

26 Jul 2019

New biomimetic culture system enables more extensive testing of drugs and gene therapies

Researchers at the University of Louisville have developed an easily reproducible system that enables them to keep slices of human hearts alive for a longer period of time, allowing more extensive testing of new drugs and gene therapies.

26 Jul 2019

Novel therapeutic strategy for treating Lafora Disease shows promise in preclinical study

A team of scientists have designed and tested in mice a novel and promising therapeutic strategy for treating Lafora Disease, a fatal form of childhood epilepsy.

25 Jul 2019

Active adhesive dressings can close wounds faster than other methods

Cuts, scrapes, blisters, burns, splinters, and punctures - there are a number of ways our skin can be broken.

25 Jul 2019

Bioinspired adhesive dressings could accelerate wound healing

Cuts, scrapes, blisters, burns, splinters, and punctures - there are a number of ways our skin can be broken. Most treatments for skin wounds involve simply placing a barrier over them (usually an adhesive gauze bandage) to keep it moist, limit pain, and reduce exposure to infectious microbes, but do not actively assist in the healing process.

25 Jul 2019

Researchers develop new compound to block therapeutic target in aggressive blood cancer

Researchers at the UNC Lineberger Comprehensive Cancer Center have discovered a hyperactive cell signal that contributes to tumor growth in an aggressive blood cancer.

23 Jul 2019

Study examines role of plastic exposure in irregular heart rhythms, arrhythmias

Calling an ambulance during an emergency, emailing a breaking news or journal article before a 5 p.m. deadline and maintaining conditions during the fifth week of a 6-week lab study, without altering the light or temperature, requires electricity and translates into time, money and lives

22 Jul 2019

Servier chooses Pall as single-source supplier for new biomanufacturing facility

Pall Corporation, a global leader in filtration, separation and purification, has been chosen by Servier, an independent international pharmaceutical company, as an exclusive technology and services provider for their Gidy, France biomanufacturing facility.

From Pall Corporation 22 Jul 2019

Don't Miss the Blood-Brain Barrier Drug Delivery (B3DD) Summit this August

The B3DD Summit will be held in Boston from August 13-15, 2019. This news story provides an overview of what you can expect at this year's conference.

From Blood-Brain Barrier Delivery Summit (B3DD) 17 Jul 2019

Implanted device uses microcurrent to exercise heart muscle in cardiomyopathy patients

In a study conducted by MedUni Vienna/Vienna General Hospital, a new type of device has been successfully used for the very first time to strengthen the weakened heart muscle in cardiomyopathy patients.

16 Jul 2019

Preclinical News and Research

Innovative technology could help treat cancer more selectively and effectively

Longer-lived, but less toxic drug may work better for pancreatic cancer

Innovative technology could treat cancer more selectively and effectively

HistoIndex, ILBS launch Center of Excellence to enhance NASH diagnostics and clinical trials

New improved model for cancer wasting syndrome cachexia

New 3D-cardiac tissue platform can predict how heart responds to drugs

New mouse model could lead to a better understanding of cachexia syndrome

Novel medical device protects healthy organs from radiation exposure during particle therapy

Study could open a new era in transplantation medicine

Combination therapy could be a promising treatment for late-stage acute lymphoblastic leukemia

Study analyzes the prevalence of antipsychotic use in youths with ADHD

New biomimetic culture system enables more extensive testing of drugs and gene therapies

Novel therapeutic strategy for treating Lafora Disease shows promise in preclinical study

Active adhesive dressings can close wounds faster than other methods

Bioinspired adhesive dressings could accelerate wound healing

Researchers develop new compound to block therapeutic target in aggressive blood cancer

Study examines role of plastic exposure in irregular heart rhythms, arrhythmias

Servier chooses Pall as single-source supplier for new biomanufacturing facility

Don't Miss the Blood-Brain Barrier Drug Delivery (B3DD) Summit this August

Implanted device uses microcurrent to exercise heart muscle in cardiomyopathy patients

Event guide: 4th LNP Formulation & Process Development Summit eBook

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