Therapeutics News and Research

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Sneaking large drug-carrying biological molecules into cells using a novel drug delivery system

Scientists from Nanyang Technological University, Singapore have developed a novel method of delivering drugs into human cells using large biological molecules, by first encasing them in a protein-based microdroplet.

16 Mar 2022

Previously unknown bacterial enzyme makes new type of polysaccharide

Strings of sugars called polysaccharides are the most abundant biopolymers on Earth. Because of their versatile and environmentally friendly properties, these molecules could eventually replace some plastics.

16 Mar 2022

INTEGRA’s VIAFLO 384 proves indispensable in neurodegeneration research

Scientists at Rejuveron Vascular Therapeutics AG, a company specializing in the development of therapies to tackle neurodegeneration, are using INTEGRA’s VIAFLO 384 handheld electronic pipette to accelerate their research.

From INTEGRA Biosciences 16 Mar 2022

New insight into SARS-CoV-2 nsp14 protein opens door to new drugs

In a recent research paper currently available on bioRxiv* preprint server, scientists from the University of Oxford in the United Kingdom and the University of Auckland in New Zealand identified several structural specificities of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that may serve as viable starting points for the development and optimization of viral inhibitors against coronavirus disease 2019 (COVID-19) and other future threats.

16 Mar 2022

Zentalis contributes $1 million to SU2C Catalyst program for research into targeted cancer therapeutics

Stand Up To Cancer and Zentalis Pharmaceuticals, Inc. today announced that Zentalis will contribute $1 million to the SU2C Catalyst program to support research that investigates the use of certain small molecule inhibitors for treating a variety of cancer types.

15 Mar 2022

Study takes a new approach to looking at de novo genetic variants in autism

About 1 in 44 children in the U.S. are diagnosed with autism spectrum disorder (ASD) by the age of 8, according to the 2018 Centers for Disease Control and Prevention surveillance. How a child's DNA contributes to the development of ASD has been more of a mystery.

15 Mar 2022

New way to deliver potential HIV vaccine using mRNA technology

Using mRNA technology like that in the COVID-19 vaccines, researchers have demonstrated a successful way to deliver a potential HIV vaccine, researchers at Duke Human Vaccine Institute report.

15 Mar 2022

Mason scientists receive DOD funding for breast cancer prevention and treatment research

George Mason University College of Science announced a $1.57 million dollar grant from the Department of Defense to fund a transformative approach for breast cancer treatment developed by scientists in Mason's Center for Drug Discovery for Rare Diseases.

15 Mar 2022

Identification of linear B cell epitopes in the SARS-CoV-2 proteome that are conserved in humans coronaviruses

Researchers identified and validated multiple linear B-cell epitopes in the SARS-CoV-2 proteomes conserved in humans coronaviruses.

15 Mar 2022

First genetic rat model of Down syndrome offers better understanding of the condition

In pursuit of better ways to test new therapies and further explore the impacts of the unique genetics associated with Down syndrome, researchers at Johns Hopkins Medicine and Tottori University in Japan have genetically engineered and characterized what is believed to be the first rat model of Down syndrome.

14 Mar 2022

Study explores SARS-CoV-2 seroprevalence among vaccinated hospital workers

A new study determined the humoral responses against SARS-CoV-2 in vaccinated hospital workers.

14 Mar 2022

Role of carboxypeptidase U in severe COVID-19

A new study measured both proCPU and CPU+CPUi over time to determine the impact of SARS-CoV-2 infection on the CPU system.

14 Mar 2022

New approach to send ‘friendly’ nano-particles into the body shows promising results

A new approach to send ‘friendly’ nano-particles into a patient’s blood stream has shown promising results by modifying the surface of these potential drug, vaccine or cancer treatment delivery objects to encourage the best result.

14 Mar 2022

Tumor cells’ 'ferroaddiction' can be exploited to deliver powerful anticancer drugs

Researchers at the University of California, San Francisco, have discovered that cells carrying the most common mutation found in human cancer accumulate large amounts of ferrous iron and that this "ferroaddiction" can be exploited to specifically deliver powerful anticancer drugs without harming normal, healthy cells.

11 Mar 2022

Modifying red blood cells to create a promising new vehicle for vaccine delivery

Physicists, chemists and immunologists at McMaster University have teamed up to modify red blood cells to transport viral agents which can safely trigger the immune system to protect the body against SARS-CoV-2, creating a promising new vehicle for vaccine delivery.

11 Mar 2022

Mice study shows how to improve long-term effectiveness of TB vaccine

Briefly blocking a key molecule when administering the only approved vaccine for tuberculosis vastly improves long-term protection against the devastating disease in mice, researchers from Texas Biomedical Research Institute report this week in the Journal of Immunology.

11 Mar 2022

Therapeutics News and Research

Sneaking large drug-carrying biological molecules into cells using a novel drug delivery system

Previously unknown bacterial enzyme makes new type of polysaccharide

INTEGRA’s VIAFLO 384 proves indispensable in neurodegeneration research

New insight into SARS-CoV-2 nsp14 protein opens door to new drugs

Zentalis contributes $1 million to SU2C Catalyst program for research into targeted cancer therapeutics

Study takes a new approach to looking at de novo genetic variants in autism

New way to deliver potential HIV vaccine using mRNA technology

Mason scientists receive DOD funding for breast cancer prevention and treatment research

Identification of linear B cell epitopes in the SARS-CoV-2 proteome that are conserved in humans coronaviruses

First genetic rat model of Down syndrome offers better understanding of the condition

Study explores SARS-CoV-2 seroprevalence among vaccinated hospital workers

Role of carboxypeptidase U in severe COVID-19

New approach to send ‘friendly’ nano-particles into the body shows promising results

Tumor cells’ 'ferroaddiction' can be exploited to deliver powerful anticancer drugs

Modifying red blood cells to create a promising new vehicle for vaccine delivery

Mice study shows how to improve long-term effectiveness of TB vaccine

Salk professors receive $3 million Endeavor Award to support lung cancer research

Lower, more frequent doses of nanomedicines may provide additional benefits for cancer patients

Potent pan-β-CoV human monoclonal antibody has in vivo activity in multiple animal models

Further optimization of cysteine-reactive pyrazoline-based covalent inhibitors for the SARS-CoV-2 Mpro

Next-generation therapeutics eBook eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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