Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Researchers discover mechanism by which lead alters nerve cells in the brain

Exposure to lead wreaks havoc in the brain, with consequences that include lower IQ and reduced potential for learning. But the precise mechanism by which lead alters nerve cells in the brain has largely remained unknown.

1 Mar 2012

Scripps Florida study to focus on four new classes of pain-relieving compounds

Scripps Florida scientists have been awarded $3.1 million by the National Institute on Drug Abuse, part of the National Institutes of Health, to study and develop several new compounds that could prove to be effective in controlling pain without the unwanted side effects common with opiate drugs, such as morphine, Oxycontin, and Vicoden.

1 Mar 2012

Brain mitochondria are dysfunctional in early-stage Alzheimer's

Mitochondria -- subunits inside cells that produce energy -- have long been thought to play a role in Alzheimer's disease. Now Mayo Clinic researchers using genetic mouse models have discovered that mitochondria in the brain are dysfunctional early in the disease.

1 Mar 2012

Inhibitory effect of serotonin 1A receptor is extremely small in people with depression

Researchers at the MedUni Vienna have, for the first time, investigated the influence of the serotonin system on the default mode network (DMN) in the human brain and discovered that, in people with depression, the inhibitory effect of the serotonin 1A receptor is extremely small. This means, says Siegfried Kasper, Head of the University Department of Psychiatry and Psychotherapy, that affected patients "are virtually never able to be mentally calm".

1 Mar 2012

LAU-0901 drug protects brain in an experimental stroke model

Research led by Nicolas Bazan, MD, PhD, Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health Sciences Center New Orleans, has found that a synthetic molecule protected the brain in a model of experimental stroke.

29 Feb 2012

Springer adds 6 new quarterly clinical review journals to medicine portfolio

Springer is adding six new quarterly clinical review journals to its existing medicine portfolio in March 2012. These new journals will expand the publisher's medical specialty coverage, focusing on dermatology, geriatrics/gerontology, nutrition, obesity, obstetrics/gynecology and respiratory care.

29 Feb 2012

Bayer receives FDA approval for lower dose formulation of ANGELIQ

Bayer HealthCare Pharmaceuticals Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved a lower dose formulation of ANGELIQ (drospirenone and estradiol) tablets to treat moderate to severe vasomotor symptoms due to menopause in women who have a uterus.

29 Feb 2012

Biogen Idec announces new easier to use injection for multiple sclerosis

The Food and Drug Administration approved the company's Avonex pen, an injection designed to reduce pain and anxiety when patients self-administer the drug. The FDA also approved a new dosing schedule for the drug intended to reduce flu-like symptoms often associated with the drug.

29 Feb 2012

Walnuts associated with better memory scores and cognitive function

Do you recall what you ate for breakfast today or dinner last night? According to new research, you may have a better chance of remembering if you include walnuts. Recent findings published in the Journal of Alzheimer's Disease report walnut consumption in a Mediterranean diet is associated with better memory scores and cognitive function.

29 Feb 2012

Scientists to speak on cultural issues pertinent to rehabilitation research

Two scientists will represent Kessler Foundation at the 2012 Race, Ethnicity and Disabilities State of the Science Conference on March 1-2 at the Crystal Gateway Marriott in Arlington, Virginia.

29 Feb 2012

Alzheimer's disease drugs may act like a bad electrician

Alzheimer's disease drugs now being tested in clinical trials may have potentially adverse side effects, according to new Northwestern Medicine research. A study with mice suggests the drugs could act like a bad electrician, causing neurons to be miswired and interfering with their ability to send messages to the brain.

29 Feb 2012

D-serine improves depressed rats' brain plasticity and memory

During depression, the brain becomes less plastic and adaptable, and thus less able to perform certain tasks, like storing memories. Researchers at the Swedish medical university Karolinska Institutet have now traced the brain's lower plasticity to reduced functionality in its support cells, and believe that learning more about these cells can pave the way for radical new therapies for depression.

29 Feb 2012

Minimally invasive treatments to be showcased at SIR's 37th Annual Scientific Meeting

The Society of Interventional Radiology will feature minimally invasive scientific advances and new discoveries that may change the way dozens of diseases are treated at its 37th Annual Scientific Meeting March 24-29 at San Francisco's Moscone Center.

29 Feb 2012

UVA, Johns Hopkins receive NIH grant to develop methods against glioblastoma

The most common primary brain cancer is glioblastoma, a highly aggressive and deadly form of tumor that kills about 95 percent of its victims within five years of diagnosis. Like other brain cancers, it is extremely difficult to treat because glioblastomas are usually deeply embedded within healthy brain tissue and therefore nearly impossible to safely access. Chemotherapy drugs cannot reach these tumors because a membrane between the bloodstream and brain tissue, called the blood-brain barrier, blocks them.

29 Feb 2012

AAN, ALS Association announce creation of Richard Olney Clinician Scientist Development Award

The American Academy of Neurology Foundation and The ALS Association are announcing the creation of the Richard Olney Clinician Scientist Development Award in ALS, named after Richard K. Olney, MD, a leading neurologist and pioneer in clinical ALS research who died late last month of ALS, also known as amyotrophic lateral sclerosis, or Lou Gehrig's disease.

29 Feb 2012

Exposure to deceptive advertising activates specific brain regions

Several specific regions of our brains are activated in a two-part process when we are exposed to deceptive advertising, according to new research conducted by a North Carolina State University professor. The work opens the door to further research that could help us understand how brain injury and aging may affect our susceptibility to fraud or misleading marketing.

29 Feb 2012

Targeting O-GlcNAcase enzyme with inhibitors might treat Alzheimer's

Slowing or preventing the development of Alzheimer's disease, a fatal brain condition expected to hit one in 85 people globally by 2050, may be as simple as ensuring a brain protein's sugar levels are maintained.

29 Feb 2012

People with TBI show decline in financial management skills

People who experience a traumatic brain injury show a marked decline in the ability to make appropriate financial decisions in the immediate aftermath and a continued impairment on complex financial skills six months later, according to new research from the University of Alabama at Birmingham.

29 Feb 2012

Mantra-based meditation shows promise against age-associated cognitive impairment

Researchers at Thomas Jefferson University Hospital determined that mantra-based meditation can have a positive impact on emotional responses to stress, fatigue and anxiety in adults with memory impairment and memory loss.

29 Feb 2012

First study to show effects of ecstasy drug on fetal and infant development

A study led by Case Western Reserve University School of Medicine, in collaboration with the University of East London UK, and Swansea University UK, is the first to show the effects of the drug ecstasy on fetal and infant development.

29 Feb 2012