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Smoking associated with increased risk of 56 diseases among Chinese adults

Smoking increases the risks of 56 diseases and kills more than 1 million adults in China each year from 22 different causes, according to new research published today in The Lancet Public Health.

1 Dec 2022

Phase 2 clinical trial of DS-1211 begins for individuals with Pseudoxanthoma Elasticum

A Phase 2 clinical trial has started of DS-1211 in individuals with Pseudoxanthoma Elasticum (PXE), a rare multisystem genetic disease that causes calcium deposits in soft tissue resulting in considerable morbidity.

1 Dec 2022

Researchers modulate the activity of potential therapeutic target for triple-negative breast cancer

Less than 20% of diagnosed breast cancers are designated "triple-negative," lacking three types of receptors often found in other breast cancer types.

30 Nov 2022

Phase 2/3 clinical trial shows that Clover’s vaccine candidate reduces household transmission of SARS-CoV-2

Clover Biopharmaceuticals, Ltd., a global clinical-stage biotechnology company developing novel vaccines and biologic therapeutics, and the International Vaccine Institute, an international nonprofit organization devoted to providing vaccines critical to global public health and based in Seoul, Korea, today announced that Clinical Infectious Diseases has published additional data from SPECTRA, a global Phase 2/3 clinical trial, that showed vaccination with SCB-2019 (CpG 1018/Alum) reduced the risk of transmitting SARS-CoV-2 infection to household members, compared to placebo participants.

30 Nov 2022

Scientists discover how an enzyme involved in DNA repair becomes vital to tumor survival

Scientists at the Francis Crick Institute, in collaboration with Artios, have identified how an enzyme involved in DNA repair (POLQ), becomes vital to the survival of certain cancers, if the cancer cells lose the ability to use a more common method of DNA repair.

30 Nov 2022

Meta-analysis reviews the incidence of new-onset diabetes in COVID-19 survivors

Researchers estimated the incidence of new-onset diabetes in survivors of coronavirus disease 2019 (COVID-19) employing random-effects meta-analyses using the generic inverse variance method.

30 Nov 2022

Miracles Start in the Lab: The quest to find a vaccine to cure AIDS

To commemorate World AIDS Day, News Medical spoke to Dr. Larry Corey, an internationally renowned expert in virology, immunology, and vaccine development, and the former president and director of Fred Hutch, about his work within the field of HIV/AIDS research and vaccine development.

30 Nov 2022

Unique scaffolding material shows significant promise in the treatment of spinal cord injury

Unique new material developed at University of Limerick in Ireland has shown significant promise in the treatment of spinal cord injury.

29 Nov 2022

Study examines cannabidiol's effect on simulated driving

Researchers use simulated driving performance to investigate whether drowsiness induced by the medical use of cannabidiol had an impact on safe driving.

29 Nov 2022

UAB and Menkes International Association sign a donation agreement to boost research in Menkes disease

These funds, coming from the Menkes International Association, will allow a research project to search for new biomarkers to establish administration and monitoring protocols for a new drug that could improve the lives of children suffering from this rare disease.

29 Nov 2022

Lower frequency of dietary salt associated with reduced risk of heart disease

Adding additional salt to foods at a lower frequency is associated with a reduced risk of heart disease, heart failure and ischemic heart disease, according to a new study published today in the Journal of the American College of Cardiology.

28 Nov 2022

Simultaneous radiation and immunotherapy can benefit mNSCLC patients with high tumor aneuploidy

In many cancer types, cancer cells try to survive by escaping attack from the immune system. These cancer cells hijack mechanisms called immune checkpoints to trick the immune system into thinking they are healthy cells.

28 Nov 2022

Green Mediterranean diet causes significant reduction in visceral adipose tissue

The green Mediterranean diet (MED) significantly reduces visceral adipose tissue, a type of fat around internal organs that is much more dangerous than the extra "tire" around your waist.

28 Nov 2022

Study provides first direct evidence of caffeine's ergogenicity on sprint running in athletics

At the international level of sport, even the smallest advantage can take an athlete from being a mere participant to a podium finisher.

28 Nov 2022

Researchers highlight the importance of localizing BRCA gene mutations for better ovarian cancer treatment

Mutations of BRCA1 and BRCA2 genes, which are inherited by 1 in 400 and 1 in 800 people respectively, significantly increase the risk of certain cancers such as ovarian, breast, pancreatic and prostate cancer.

28 Nov 2022

Are nasal-spray vaccines the solution to respiratory infectious diseases?

A recent study published in the journal Trends in Molecular Medicine reviewed the current efforts in developing nasal vaccines, delivery systems, and clinical applications for preventing respiratory illnesses.

28 Nov 2022

Multivalent mRNA-based vaccine may serve as a preventative measure against future flu pandemics

An experimental mRNA-based vaccine against all 20 known subtypes of influenza virus provided broad protection from otherwise lethal flu strains in initial tests, and thus might serve one day as a general preventative measure against future flu pandemics, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

25 Nov 2022

Clinical Trial News and Research

Smoking associated with increased risk of 56 diseases among Chinese adults

Phase 2 clinical trial of DS-1211 begins for individuals with Pseudoxanthoma Elasticum

Researchers modulate the activity of potential therapeutic target for triple-negative breast cancer

Phase 2/3 clinical trial shows that Clover’s vaccine candidate reduces household transmission of SARS-CoV-2

Scientists discover how an enzyme involved in DNA repair becomes vital to tumor survival

Meta-analysis reviews the incidence of new-onset diabetes in COVID-19 survivors

Miracles Start in the Lab: The quest to find a vaccine to cure AIDS

Unique scaffolding material shows significant promise in the treatment of spinal cord injury

Study examines cannabidiol's effect on simulated driving

UAB and Menkes International Association sign a donation agreement to boost research in Menkes disease

Lower frequency of dietary salt associated with reduced risk of heart disease

Simultaneous radiation and immunotherapy can benefit mNSCLC patients with high tumor aneuploidy

Green Mediterranean diet causes significant reduction in visceral adipose tissue

Study provides first direct evidence of caffeine's ergogenicity on sprint running in athletics

Researchers highlight the importance of localizing BRCA gene mutations for better ovarian cancer treatment

Are nasal-spray vaccines the solution to respiratory infectious diseases?

Multivalent mRNA-based vaccine may serve as a preventative measure against future flu pandemics

Can acupuncture alleviate lower back and pelvic pain in pregnant women?

Additional six weeks of anti-clotting treatment reduces further clot risk after distal DVT

Study demonstrates that Paxlovid protects severe COVID-19–associated outcomes among persons for whom it is recommended

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