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Study sheds light on immune cells' ability to collectively migrate through complex environments

When fighting disease, our immune cells need to reach their target quickly. Researchers at the Institute of Science and Technology Austria (ISTA) now discovered that immune cells actively generate their own guidance system to navigate through complex environments.

1 Sep 2023

New research could help improve the effectiveness of immunotherapy for people with brain tumors

A study led by researchers at the UCLA Jonsson Comprehensive Cancer Center sheds new light on why tumors that have spread to the brain from other parts of the body respond to immunotherapy while glioblastoma, an aggressive cancer that originates in the brain, does not.

1 Sep 2023

Combination of cediranib and lenalidomide does not improve outcomes in advanced thyroid cancer

Results of a multicenter phase II clinical trial led by the University of Chicago Medicine Comprehensive Cancer Center show that adding an immunomodulatory agent to treatment with the targeted tyrosine kinase inhibitor (TKI) cediranib did not make a difference in outcomes for treating patients with an advanced form of thyroid cancer that develops from thyroid follicular cells called differentiated thyroid cancer (DTC).

1 Sep 2023

Amgen to discuss application for LUMAKRAS® (sotorasib) for the treatment of KRAS G12C-positive NSCLC at FDA advisory committee meeting

Amgen today announced the U.S. Food and Drug Administration (FDA) Oncologic Drugs Advisory Committee (ODAC) will review data supporting the supplemental New Drug Application (sNDA) for the full approval of LUMAKRAS® (sotorasib) for adults with previously treated locally advanced or metastatic KRAS G12C-mutated non-small cell lung cancer (NSCLC) at a meeting on Oct. 5, 2023.

From AMGEN 1 Sep 2023

Antioxidants stimulate the formation of new blood vessels in lung cancer tumors

Vitamin C and other antioxidants stimulate the formation of new blood vessels in lung cancer tumors, a new study from Karolinska Institutet published in The Journal of Clinical Investigation shows.

31 Aug 2023

New liquid biopsy technology uses RNA "dark matter" to detect cancer

Cancer is most treatable in its early stages, so finding innovative and non-invasive methods to diagnose cancer early on is crucial for fighting the disease.

31 Aug 2023

The Clinical Importance of Circulating Tumor DNA

Cancer remains a leading killer among medical causes of death worldwide.

31 Aug 2023

New discoveries about a type of immune cells could pave the way for improved immunotherapies

Fresh discoveries about a type of immune cells could give lung cancer patients a more accurate prognosis and better identify who will benefit from immunotherapies.

30 Aug 2023

Exercise may help improve sexual function in prostate cancer patients

Prostate cancer is one of the most common forms of cancer in the world, but not only does it put the lives of those diagnosed at risk, but can also severely impact patient quality of life due to side-effects of treatment.

30 Aug 2023

Unlocking tumor immune evasion: IL1RL1+ Treg cells and CAFs collaborate for immunotherapy resistance

Researchers demonstrated that the crosstalk between IL1RL1+ regulatory T-cells (Treg) and cancer-associated fibroblasts (CAFs) drives the tissue repairing.

30 Aug 2023

Light-driven bacteria could be used to target and kill cancer cells

Targeting malignant tumors with high precision is challenging for biomedical researchers. However, this scenario is likely to witness a paradigm shift in the near future, through the use of specially engineered bacteria, that can eliminate malignant cells efficiently.

29 Aug 2023

Non-alcoholic steatohepatitis progression blocked by ginger essential oil

Researchers explore the potential utility of ginger essential oil in preventing NASH.

29 Aug 2023

Innovative insights into effects of hematopoietic changes on colon cancer, unveiling therapeutic avenues

Researchers investigated whether bone marrow-derived cells contribute to colitis-associated colon cancer.

29 Aug 2023

Inflammatory diets raise dementia and Alzheimer's risk

This research study links higher Dietary Inflammatory Index (DII) scores to an increased risk of developing dementia, specifically Alzheimer's disease. The findings suggest that anti-inflammatory diets may offer a preventive strategy for dementia, underlining the need for further research to validate these associations.

28 Aug 2023

How diet and exercise may rewrite the Alzheimer's script at a molecular level

Researchers explore how lifestyle changes like diet and physical activity can influence microRNA expression in Alzheimer's patients, potentially offering new therapeutic avenues. The study fills a research gap in understanding how such lifestyle modifications could affect molecular mechanisms implicated in Alzheimer’s disease.

28 Aug 2023

Scientific breakthrough could someday save the lives of children with rhabdomyosarcoma

"Every successful medicine has its origin story. And research like this is the soil from which new drugs are born," says Cold Spring Harbor Laboratory Professor Christopher Vakoc.

28 Aug 2023

Study confirms the anti-cancer effects of Kencur extract

You may know it as an aromatic spice to add flavor to your dishes or as a soothing herbal remedy to use for upset stomachs, but researchers from Osaka Metropolitan University have uncovered promising findings that Kencur, a tropical plant in the ginger family native to Southeast Asia, possesses anti-cancer effects.

28 Aug 2023

A comprehensive online resource allows for the exploration of interactions between mutational signatures and topographical features across human cancer

An online resource for studying the relationship between mutational signatures and topographical characteristics across human cancer.

28 Aug 2023

The potential of targeting mitochondria-associated programmed cell death for age-related disease treatment

The review summarized the involvement of mitochondria in age-related disease progression and highlighted its potential as a therapeutic target of these diseases.

28 Aug 2023

Beyond traditional models: 3D bioprinted tumor microenvironment unlocks resistance insights

Researchers developed a three-dimensional (3D) biologically printed in vitro model of the breast cancer tumor microenvironment.

28 Aug 2023

Tumor News and Research

Study sheds light on immune cells' ability to collectively migrate through complex environments

New research could help improve the effectiveness of immunotherapy for people with brain tumors

Combination of cediranib and lenalidomide does not improve outcomes in advanced thyroid cancer

Amgen to discuss application for LUMAKRAS® (sotorasib) for the treatment of KRAS G12C-positive NSCLC at FDA advisory committee meeting

Antioxidants stimulate the formation of new blood vessels in lung cancer tumors

New liquid biopsy technology uses RNA "dark matter" to detect cancer

The Clinical Importance of Circulating Tumor DNA

New discoveries about a type of immune cells could pave the way for improved immunotherapies

Exercise may help improve sexual function in prostate cancer patients

Unlocking tumor immune evasion: IL1RL1+ Treg cells and CAFs collaborate for immunotherapy resistance

Light-driven bacteria could be used to target and kill cancer cells

Non-alcoholic steatohepatitis progression blocked by ginger essential oil

Innovative insights into effects of hematopoietic changes on colon cancer, unveiling therapeutic avenues

Inflammatory diets raise dementia and Alzheimer's risk

How diet and exercise may rewrite the Alzheimer's script at a molecular level

Scientific breakthrough could someday save the lives of children with rhabdomyosarcoma

Study confirms the anti-cancer effects of Kencur extract

A comprehensive online resource allows for the exploration of interactions between mutational signatures and topographical features across human cancer

The potential of targeting mitochondria-associated programmed cell death for age-related disease treatment

Beyond traditional models: 3D bioprinted tumor microenvironment unlocks resistance insights

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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