B Cell News and Research

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Brainwide circuitry mapping reveals how psilocybin drives therapeutic neural rewiring

An international collaboration led by Cornell University researchers used a combination of psilocybin and the rabies virus to map how – and where – the psychedelic compound rewires the connections in the brain.

5 Dec 2025

Protein network locks ABCC4 transporters in place to maintain cyclic AMP signaling levels

When a cell receives a message from outside, it generates a molecule called cyclic AMP (cAMP) to relay this message. To ensure the signal reaches the correct effector without triggering pathways accidentally, cAMP levels must be maintained around their point of origin and at the right level.

5 Dec 2025

CRISPR-based Cellgorithm technology ushers in a new era of cell programming

Syntax Bio, a synthetic biology company programming the next generation of cell therapies, today announced the publication of new research in Science Advances detailing the company's CRISPR-based Cellgorithm technology, which lays the groundwork for programmable control of gene activity in human stem cells and offers an alternative to the slow, variable manual processes researchers use today.

5 Dec 2025

Tenascin C as a key to restoring muscle regeneration in aging

As we age, the muscles we rely on for daily activities tend to become less reliable. With enough decline, even normal movements such as getting out of bed become risky.

5 Dec 2025

New atomic structure reveals how NBCn1 transporter protein aids breast cancer cell survival

UCLA scientists have characterized the structure and function of a key survival protein in breast cancer cells that helps explain how these tumors resist environmental stress and thrive in acidic, low-oxygen environments that would normally be toxic to healthy cells.

5 Dec 2025

Researchers highlight five pathways through which microplastics can harm the brain

Microplastics could be fueling neurodegenerative diseases like Alzheimer's and Parkinson's, with a new study highlighting five ways microplastics can trigger inflammation and damage in the brain.

5 Dec 2025

Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer

Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows quickly, spreads early and lacks the hormone receptors that make other breast cancers treatable with targeted therapies.

5 Dec 2025

Study shines light on how P2X4 receptor can be inhibited

A study carried out by the University of Bonn and the University Hospital Bonn throws light on how an important receptor can be inhibited.

5 Dec 2025

Maximizing bioprocess efficiency through real-time cell density monitoring

Discover how real-time cell density monitoring boosts yield, lowers media costs, and improves viability in bioprocessing.

From Hamilton AG 5 Dec 2025

Study provides first molecular evidence that ferroptosis can drive neurodegeneration

Researchers at Helmholtz Munich, the Technical University of Munich and the LMU University Hospital Munich uncovered a mechanism that protects nerve cells from premature cell death, known as ferroptosis.

4 Dec 2025

Bacterial enzyme linked to heart complications in pneumonia

Pneumonia is a disease that burdens the healthcare system with more that 1.2 million emergency room visits each year and more than 41,000 adult deaths in the United States.

4 Dec 2025

Engineered herpes virus activates potent immune responses against glioblastoma

Researchers at Mass General Brigham have modified a herpes simplex virus (HSV-1) that stimulates the immune system to attack glioblastoma cells.

4 Dec 2025

Urine cfDNA patterns emerge as a promising tool for diagnosing bladder cancer

Researchers have discovered that analyzing specific patterns of cell-free DNA (cfDNA) fragmentation in a simple urine sample can effectively diagnose and stage bladder cancer, offering a much-needed alternative to invasive procedures like cystoscopies.

4 Dec 2025

Early pregnancy placenta models show significant effects from PFAS exposure

Per- and polyfluoroalkyl substances (PFAS) are a group of nearly 10,000 long-lasting chemical compounds that stay in the environment and have been linked to adverse health effects on humans, including pregnant women and their unborn children.

4 Dec 2025

Scientists uncover why SETX-deficient cancer cells rely on error-prone DNA repair

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break-when both sides of the DNA helix are cut at once.

4 Dec 2025

Researchers capture high-resolution footage of flu viruses entering human cells

For the first time, researchers have observed live and in high resolution how influenza viruses infect living cells. This was possible thanks to a new microscopy technique, which could now help to develop antiviral therapies in a more targeted manner.

4 Dec 2025

Study uncovers strategy to sensitize estrogen receptor–positive breast tumors to immunotherapy

A study led by researchers at the Hospital del Mar Research Institute advances one of the most significant milestones in breast cancer treatment, making immunotherapy effective against the most common tumor type, estrogen receptor-positive or luminal breast cancer.

4 Dec 2025

Organ-on-a-chip system reveals how aging weakens vaccine-driven anti-cancer immunity

Dr. Vadim Jucaud's lab at the Terasaki Institute has introduced a new organ-on-a-chip platform that recapitulates age-dependent immune responses, offering a more accurate testing bed for evaluating cancer vaccine performance in older adults, the population most affected by cancer and often overlooked in traditional preclinical testing.

4 Dec 2025

New drug combination shows promise for overcoming resistance in ovarian cancer

Researchers at the University of Colorado Cancer Center have discovered a novel therapy combination that could offer new hope to ovarian cancer patients who do not respond to existing treatments.

4 Dec 2025

Common childhood virus linked to bladder cancer later in life

Tackling a common childhood virus could open the door to preventing bladder cancer, according to new research funded by Kidney Research UK and York Against Cancer.

4 Dec 2025

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B Cell News and Research

Brainwide circuitry mapping reveals how psilocybin drives therapeutic neural rewiring

Protein network locks ABCC4 transporters in place to maintain cyclic AMP signaling levels

CRISPR-based Cellgorithm technology ushers in a new era of cell programming

Tenascin C as a key to restoring muscle regeneration in aging

New atomic structure reveals how NBCn1 transporter protein aids breast cancer cell survival

Researchers highlight five pathways through which microplastics can harm the brain

Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer

Study shines light on how P2X4 receptor can be inhibited

Maximizing bioprocess efficiency through real-time cell density monitoring

Study provides first molecular evidence that ferroptosis can drive neurodegeneration

Bacterial enzyme linked to heart complications in pneumonia

Engineered herpes virus activates potent immune responses against glioblastoma

Urine cfDNA patterns emerge as a promising tool for diagnosing bladder cancer

Early pregnancy placenta models show significant effects from PFAS exposure

Scientists uncover why SETX-deficient cancer cells rely on error-prone DNA repair

Researchers capture high-resolution footage of flu viruses entering human cells

Study uncovers strategy to sensitize estrogen receptor–positive breast tumors to immunotherapy

Organ-on-a-chip system reveals how aging weakens vaccine-driven anti-cancer immunity

New drug combination shows promise for overcoming resistance in ovarian cancer

Common childhood virus linked to bladder cancer later in life

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