Malignant News and Research

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Elderly population faces escalating melanoma incidence over three decades

The prevalence and fatality rates of cutaneous malignant melanoma (CMM) have been rising, particularly among the elderly.

28 Oct 2024

Genomic technology used to improve understanding of Marjolin's ulcer

Researchers utilized specialized genomic technology at the University of Calgary to enhance our understanding of Marjolin's ulcer (MU), a rare, highly aggressive skin cancer that affects chronic wounds that can often arise from established scars like those caused by severe burns.

28 Oct 2024

RNA modifications and their role in cancer development

Cancer, a disease with global impact, is intricately linked to dysregulated gene expression, which is influenced by both genetic mutations and epigenetic changes, including RNA modifications.

25 Oct 2024

Targeted therapy and immunotherapy improve outcomes in rare thyroid cancer

Researchers from The University of Texas MD Anderson Cancer Center demonstrated that anti-PD-L1 immunotherapy in combination with mutation-directed targeted therapy extended overall survival (OS) in patients with anaplastic thyroid carcinoma (ATC). Findings from the Phase II single center study published today in JAMA Oncology.

24 Oct 2024

3D-printed model created to mimic cancer metastasis

Scientists have created a 3D-printed model to mimic the specific conditions that spur the spread of cancer cells.

23 Oct 2024

Groundbreaking findings on TET2 pathway open doors for targeted blood cancer treatments

Approximately 30% of individuals with myeloid malignancy diseases have a mutation in a certain gene called tet methylcytosine dioxygenase 2 (TET2).

23 Oct 2024

Cutting off cancer cells' access to fats may enhance cancer therapy

Cutting off cancer cells' access to fat may help a specific type of cancer treatment work more effectively, reports a study by Van Andel Institute scientists.

22 Oct 2024

ALS drug shows promise in targeting glioblastoma stem cells

Glioblastoma is the most common – and the most malignant – primary brain tumor in adults. It's aggressive and incurable.

17 Oct 2024

U.S. cancer detection severely disrupted during first year of COVID-19, shows incomplete recovery in second year

A JAMA study finds COVID-19 caused a 127,931 deficit in cancer diagnoses in 2020, with recovery in 2021 influenced by demographic and community characteristics.

17 Oct 2024

Two programs found to control invasion and inflammation in segregated tumor cell populations

Understanding in depth how tumors evolve to become malignant is the objective of the latest study led by the Cell Plasticity in Development and Disease laboratory, directed by ángela Nieto at the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University (UMH) of Elche.

16 Oct 2024

Revolutionizing AI training by emulating physician education

When human radiologists examine scans, they peer through the lens of decades of training. Extending from college to medical school to residency, the road that concludes in a physician interpreting, say, an X-ray, includes thousands upon thousands of hours of education, both academic and practical, from studying for licensing exams to spending years as a resident.

15 Oct 2024

Renowned pancreatic surgeon Dr. Katherine A. Morgan joins NYU Langone

Katherine A. Morgan, MD, recognized internationally for her expertise in pancreatic surgery, is joining NYU Langone Health as a professor in the Department of Surgery and as section chief of pancreas surgery in the Division of Hepatobiliary and Pancreatic Surgery.

14 Oct 2024

Computational tools unlock the secrets of the genome

In collaboration with the International Conference on Research in Computational Molecular Biology (RECOMB), Genome Research publishes a collection of 20 computational methods and their applications in genomics including spatial, single-cell, and long-read sequencing.

13 Oct 2024