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Oral AD109 improves sleep apnea severity but tolerability remains a challenge

AD109, an investigational once-daily oral combination of aroxybutynin and atomoxetine, significantly improved airway obstruction and oxygenation in adults with mild-to-severe obstructive sleep apnea who could not use PAP therapy. However, symptom improvements did not clearly differ from placebo, and about one in five AD109 recipients discontinued treatment due to adverse events.

21 May 2026

Restoring ADAR2 enzyme reduces metastatic spread in osteosarcoma

Osteosarcoma is the most common primary bone cancer in children, adolescents, and young adults. Although chemotherapy and surgery have improved survival for localized disease, outcomes remain poor when tumors spread to the lungs or return after treatment.

20 May 2026

Patient intuition leads to urgent open-heart surgery at NYU Langone Hospital—Brooklyn

Shana Hale, a Brooklyn mother of two and a technology executive, noticed a mild burning sensation in her chest during her daily walks last summer.

20 May 2026

Biomimetic nanocomposite hydrogel promotes tendon healing and tissue regeneration

The new system, termed KGN@PB@CM, combines several advanced elements. Prussian blue (PB) nanozymes act as potent reactive oxygen species (ROS) scavengers, while kartogenin (KGN)-a small molecule that promotes stem cell migration and tenogenic differentiation-is loaded onto the PB core.

20 May 2026

Vitamin D deficiency linked to higher postoperative breast cancer pain

Vitamin D deficiency is associated with more moderate to severe pain following breast cancer surgery and an increased consumption of opioid drugs, finds research published online in the journal Regional Anesthesia & Pain Medicine.

19 May 2026

Miniaturization in Medtech

Medical devices are becoming smaller, lighter and more portable. From handheld diagnostic tools to wearable infusion pumps and compact surgical instruments, reduced size is now a defining feature of many new Medtech products.

From SMB Bearings 19 May 2026

Study supports flexible blood transfusion options in emergency trauma care

Giving whole blood or the component parts of blood are equally effective options for paramedics and emergency medical technicians to use in treating patients with severe, traumatic bleeding before arriving at the hospital, according to a large, nationwide trial directed by University of Pittsburgh and UPMC clinicians and scientists.

19 May 2026

New report highlights widening cardiovascular health inequalities across Europe

Cardiovascular disease (CVD) remains one of Europe's biggest health challenges, according to new data from the European Society of Cardiology (ESC) Atlas of Cardiology, published in the European Heart Journal.

19 May 2026

Surgical training program for community health officers slashes maternal mortality risk

Maternal mortality in Sierra Leone used to be among the highest in the world. A 15-year-old non-profit program that trains community health officers to do life-saving surgeries has helped slash that risk by two-thirds.

18 May 2026

Hydrogel breakthrough offers significant advance in type 1 diabetes treatment

Researchers from the University of Geneva (UNIGE) and Geneva University Hospitals (HUG) have reached a significant advance in the fight against type 1 diabetes. Using an innovative hydrogel that supports insulin-producing cells once transplanted into the body, the team successfully regulated blood sugar levels in diabetic mice.

18 May 2026

Evidence shows RF-TC improves seizure control by altering brain networks

Drug-resistant epilepsy affects millions of people worldwide and remains one of the most difficult neurological disorders to treat. For patients whose seizures continue despite medication, surgical removal of seizure-causing tissue can be effective.

15 May 2026

Endoscopic sleeve gastroplasty outperforms oral semaglutide in short-term weight loss

A comparative study, presented at ESGE Days 2026, has found that endoscopic sleeve gastroplasty (ESG) is associated with significantly greater short-term weight loss than oral semaglutide in adults with obesity.

15 May 2026

Study identifies breakthrough drug combination for early-stage Peyronie’s

Combining two widely prescribed drug classes could provide the first effective treatment for early-stage Peyronie's disease, according to a new study published in The Journal of Sexual Medicine.

15 May 2026

Perioperative medicine emerges as a system wide strategy for better surgery outcomes

Perioperative medicine is emerging as a transformative, comprehensive, system-wide approach to patient care before, during, and after surgery – that reduces complication rates and hospital days, provides better health outcomes, and improves health system performance, according to a special article in the Online First edition of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists (ASA).

14 May 2026

Wearable wireless polygraph tracks hidden stress signals

Northwestern University engineers have developed a small, wireless polygraph system you can wear.

13 May 2026

Next-generation cancer therapy shows early promise as treatment candidate for glioblastoma

A next-generation cancer therapy being developed at McMaster University has shown early promise as a treatment candidate for glioblastoma, the most aggressive and most common type of primary brain cancer in adults.

13 May 2026

Obesity drugs and surgery linked to greater fat-free mass loss

A new systematic review and meta-analysis of studies presented at this year's European Congress on Obesity in Istanbul, Turkey (12-15 May) shows that diet and exercise interventions result in a lower proportion of fat-free mass loss compared with obesity surgery or obesity drugs among people undergoing a weight loss of 10% or more.

13 May 2026

Tranexamic acid modestly reduces bleeding after cesarean delivery in women

Giving tranexamic acid to women with placenta praevia (when the placenta covers the cervical opening) undergoing cesarean birth leads to a significant yet modest reduction in severe bleeding after delivery with no evidence of an increase in serious adverse events, finds a trial from China published by The BMJ today.

13 May 2026

Survey finds one in three women suffer silently with pelvic prolapse

Up to half of all women will experience some degree of pelvic organ prolapse in their lifetime. The condition can cause incontinence, constipation and the descent of the bladder or uterus into the vagina.

13 May 2026