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Mutation-acquiring potential of coronaviruses and efficacies of current COVID-19 vaccines against parent and mutant strains of SARS-CoV-2

Researchers reviewed the antibody resistance exhibited by SARS-CoV-2 variants.

18 Apr 2022

RNA interference triggers that target SARS-CoV-2 genome

Researchers screened ribonucleic acid interference against SARS-CoV-2.

18 Apr 2022

Delivery technologies of mRNA and pDNA for advanced therapeutic applications

Innovation Center of NanoMedicine (Center Director: Prof. Kazunori Kataoka) has announced that Prof. Satoshi Uchida (Principal Research Scientist), who is also Associated Professor of the Kyoto Prefectural University of Medicine, published an article review about non-viral messenger RNA (mRNA) and plasmid DNA (pDNA) delivery by addressing the various delivery technologies of mRNA and pDNA, from basic research to therapeutic and clinical application; Pharmaceutics 2022, 14(4), 810.

15 Apr 2022

Genomic characterization of the circulating SARS-CoV-2 lineages in Papua New Guinea

A recent study characterized the SARS-CoV-2 lineages circulating in Papua New Guinea during the second wave of COVID-19.

15 Apr 2022

Vaccine breakthrough infections with omicron sub-lineages induce cross-neutralizing antibodies

A new study evaluated the cross-neutralizing potency of serum samples collected from individuals who have been infected with the omicron variant of SARS-CoV-2.

14 Apr 2022

Study explores role of APOBEC-mediated RNA editing in SARS-CoV-2 fitness

A new study investigated whether APOBEC proteins can directly edit the RNA sequence of SARS-CoV-2 to generate C-to-U mutations.

14 Apr 2022

Recent advances in non-viral nano-vector delivery of CRISPR/Cas9 genome editing payloads

Researchers reviewed non-viral nano-vectors used for delivering the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-mediated genome editing system.

14 Apr 2022

Structural differences between SARS-CoV-1 and SARS-CoV-2 RBDs

A new study compares the SARS-CoV-2 RBD to the SARS-CoV RBD using computational methods to understand their binding affinities to ACE2.

13 Apr 2022

Regulation of alternative splicing goes haywire in cells of a newly formed embryo

Alternative splicing is a fundamental biological process that allows cells to make many different types of mRNAs and proteins from a limited number of genes. For many animals, including humans, it is a feature that is essential for the development of complex cells such as muscles or neurons.

13 Apr 2022

The transmission dynamics of key SARS-CoV-2 mutations revealed by subtyping in new study

In a new study, researchers devised a method for reducing the size of a large collection of SARS-CoV-2 genomes by combining correlated single nucleotide variation sets with allelic association.

13 Apr 2022

Zika virus can mutate to become more infective and dangerous, finds study

LA JOLLA, CA - Researchers at La Jolla Institute for Immunology (LJI) have found that Zika virus can mutate to become more infective - and potentially break through pre-existing immunity.

13 Apr 2022

Treg cell Notch receptors drive SARS-CoV-2-induced MIS-C

In a recent study under consideration at Nature Portfolio Journal and posted to the Research Square* preprint server, researchers demonstrated the evolution of multi-system inflammatory syndrome in children (MIS-C) following acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

12 Apr 2022

Genome News and Research

Mutation-acquiring potential of coronaviruses and efficacies of current COVID-19 vaccines against parent and mutant strains of SARS-CoV-2

RNA interference triggers that target SARS-CoV-2 genome

Delivery technologies of mRNA and pDNA for advanced therapeutic applications

Genomic characterization of the circulating SARS-CoV-2 lineages in Papua New Guinea

Vaccine breakthrough infections with omicron sub-lineages induce cross-neutralizing antibodies

Study explores role of APOBEC-mediated RNA editing in SARS-CoV-2 fitness

Recent advances in non-viral nano-vector delivery of CRISPR/Cas9 genome editing payloads

Structural differences between SARS-CoV-1 and SARS-CoV-2 RBDs

Regulation of alternative splicing goes haywire in cells of a newly formed embryo

The transmission dynamics of key SARS-CoV-2 mutations revealed by subtyping in new study

Zika virus can mutate to become more infective and dangerous, finds study

Treg cell Notch receptors drive SARS-CoV-2-induced MIS-C

Development of 18 monoclonal antibodies against 9 SARS-CoV-2 proteins

Dysregulated retroelements associated with autoimmunity in COVID-19

Experimental tool can precisely pick out interactions between immune cell and target antigen

Epidemiologic characteristics of SARS-CoV-2 Omicron and Delta variant infection cases in Cantabria, Spain

Exploring vaccine effectiveness against SARS-CoV-2 Omicron and Delta variants in adolescents

Unique heightened aggregation of SARS-CoV-2 Delta variant spike pseudotyped particles

Evidence of an increased risk of neurodegeneration after SARS-CoV-2 infection

New research on SARS-CoV-2 Omicron variant mutations and sotrovimab therapy

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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