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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Study evaluates interactions between SARS-CoV-2 proteins and viral and host RNA

A new study investigated the interactions between SARS-CoV-2 proteins and viral and host ribonucleic acid in virus-infected cells.

22 Mar 2022

Posaconazole found to be effective as a small molecule fusion inhibitor against SARS-CoV-2 variants

Researchers evaluated the importance of the Ex3Lx6L motif in SARS-CoV-2 entry into host cells mediated by the spike protein syncytium formation and membrane fusion.

22 Mar 2022

Human parainfluenza type 3 virus outbreak in Seoul during SARS-CoV-2 pandemic

In a recent study posted to the bioRxiv* preprint server, researchers conducted a phylogenetic investigation of the human parainfluenza type 3 virus strain (HPIV3) that caused an outbreak in South Korea amid the coronavirus disease 2019 (COVID-19) pandemic.

22 Mar 2022

Environmental surveillance for early detection of COVID-19 outbreaks

A recent study posted to the medRxiv* preprint server investigated whether environmental samples could serve as early indicators for detecting severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in large communities.

22 Mar 2022

Is COVID-19 on the verge of ending?

Researchers explore the changes arising in SARS-CoV-2 over time.

21 Mar 2022

A circRNA COVID vaccine with potential to neutralize SARS-CoV-2 variants

Researchers demonstrate the broad neutralization potential of a strategically engineered circRNA using mice as a model system.

21 Mar 2022

Could COVID-19 spread through wastewater in the Thames?

Researchers investigate the presence of SARS-CoV-2 infectious particles and its RNA material in the Thames and other rivers.

21 Mar 2022

Using CRISPR/Cas to develop biosafety materials

Researchers discuss the use of the highly efficient CRISPR/Cas technologies to identify viral genome sequences for biosafety purposes.

21 Mar 2022

SARS-CoV-2 transmitters have 3 times higher viral loads than non-transmitters

Researchers discuss the difference between transmitters and non-transmitters of SARS-CoV-2 in terms of their mean viral load.

21 Mar 2022

Mount Sinai launches phase 1 study to evaluate the safety, immunogenicity of egg-based COVID-19 vaccine

A team of clinical investigators at the Icahn School of Medicine at Mount Sinai has announced the launch of a Phase 1, open-label, placebo-controlled study to evaluate the safety and immunogenicity of an egg-based COVID-19 vaccine in healthy, vaccinated adults who have never been infected with COVID-19.

21 Mar 2022

New computational approach creates spatial maps of single-cell data within tissues

A new computational approach developed by researchers at The University of Texas MD Anderson Cancer Center successfully combines data from parallel gene-expression profiling methods to create spatial maps of a given tissue at single-cell resolution.

21 Mar 2022

Saliva tests detect SARS-CoV-2 virus more quickly than nasal swabs

Genetic testing of saliva samples identifies the SARS-CoV-2 virus more quickly than testing of nasal swabs. The research is published March 21 in Microbiology Spectrum, a journal of the American Society for Microbiology.

21 Mar 2022

NIH launches Molecular Characterization Initiative for pediatric tumors

In support of President Biden's Cancer Moonshot℠ goal of fostering data sharing in cancer research, the National Cancer Institute, part of the National Institutes of Health, has launched the Molecular Characterization Initiative for pediatric tumors.

21 Mar 2022

Study explores novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2

In a new study, researchers aimed to determine if peptidyl-arginine deiminases inhibitors may be used as a novel class of host-targeting antivirals against human coronaviruses.

21 Mar 2022

Study evaluates colorimetric sensors for SARS-CoV-2 detection using gold nanoparticles

A new study reported the development of colorimetric sensors for the detection of SARS-CoV-2 ribonucleic acid-dependent RNA polymerase, envelope, and spike genes.

21 Mar 2022

Study unveils several natural marine products as potential agents against SARS-CoV-2

A recent study, published in the Journal of Natural Products of the American Chemical Society and American Society of Pharmacognosy, highlighted three natural marine products as potent inhibitors of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – without any apparent toxic effects for human lung cells.

21 Mar 2022

RNA News and Research

Further Reading

Study evaluates interactions between SARS-CoV-2 proteins and viral and host RNA

Posaconazole found to be effective as a small molecule fusion inhibitor against SARS-CoV-2 variants

Human parainfluenza type 3 virus outbreak in Seoul during SARS-CoV-2 pandemic

Environmental surveillance for early detection of COVID-19 outbreaks

Is COVID-19 on the verge of ending?

A circRNA COVID vaccine with potential to neutralize SARS-CoV-2 variants

Could COVID-19 spread through wastewater in the Thames?

Using CRISPR/Cas to develop biosafety materials

SARS-CoV-2 transmitters have 3 times higher viral loads than non-transmitters

Mount Sinai launches phase 1 study to evaluate the safety, immunogenicity of egg-based COVID-19 vaccine

New computational approach creates spatial maps of single-cell data within tissues

Saliva tests detect SARS-CoV-2 virus more quickly than nasal swabs

NIH launches Molecular Characterization Initiative for pediatric tumors

Study explores novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2

Study evaluates colorimetric sensors for SARS-CoV-2 detection using gold nanoparticles

Study unveils several natural marine products as potential agents against SARS-CoV-2

Low levels of SARS-CoV-2 viremia associated with ‘COVID placentitis’ and stillbirths

How does the non-structural protein 1 affect COVID-19 pathogenicity?

Omicron BA.1.1 and BA.2 subvariants with new mutations in New Zealand and Hong Kong

UT Dallas researchers explore origins of chronic pain and the potential for better treatments

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