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Research demonstrates multivalent nanobodies overcome SARS-CoV-2 variant mutations

In a recent bioRxiv* preprint paper, researchers isolated anti-RBD nanobodies from llamas and “nanomice” (they engineered to produce VHHs cloned from alpacas, dromedaries and camels).

10 Mar 2021

Study: COVID-19 test package can reduce infections and mortality at justifiable cost

Mailing a package of SARS-CoV-2 tests to every household in America and asking people to use them once a week could greatly reduce total infections and mortality at a justifiable cost, a new study led by the Yale School of Public Health finds.

10 Mar 2021

Analysis shows moderate evidence for SARS-CoV-2 recombination

Recently, a team of researchers from the US performed a comprehensive recombination analysis across all medically relevant human coronaviruses, including 158,118 public seasonal hCoV, SARS-CoV-1, SARS-CoV-2, and MERS-CoV genome sequences with the help of the RDP4 software. They aimed at identifying the current and future risks of the emergence of recombinants of SARS-CoV-2

10 Mar 2021

2% of individuals carry 90% of SARS-CoV-2 virions: Study of 72,500 tests

In a new study published on the medRxiv* preprint server, researchers analyzed viral loads from pre-symptomatic and asymptomatic individuals in an extensive university surveillance program.

9 Mar 2021

SARS-CoV-2 variants rapidly arise in non-human hosts, potential risk for human reinfection

The study, published on the preprint server bioRxiv*, highlights the need to study viral evolution and pathogenesis in human and animal hosts. This could help prevent future outbreaks that may mimic the magnitude of the current COVID-19 pandemic.

9 Mar 2021

Somatic gene mutations in brain cells could contribute to schizophrenia pathology

Schizophrenia is a neurodevelopmental disorder that disrupts brain activity producing hallucinations, delusions, and other cognitive disturbances. Researchers have long searched for genetic influences in the disease, but genetic mutations have been identified in only a small fraction--fewer than a quarter--of sequenced patients.

9 Mar 2021

Sugar-sweetened soda intake associated with increased risk of mortality among breast cancer patients

New research from the University at Buffalo suggests that breast cancer patients who drink sugar-sweetened beverages regularly are at increased risk for death from any cause and breast cancer in particular.

9 Mar 2021

A genetic variant of TMPRSS2 may confer protection against severe COVID-19

Among a large sample of COVID-19 patients, researchers found that a genetic variant – caused by an amino acid substitution from valine to methionine – is associated with a reduced chance of severe disease.

9 Mar 2021

Optimized SARS-CoV-2 vaccine candidate could be less reactogenic, say researchers

A new study, released as a preprint on the bioRxiv* server, reports an optimized coronavirus disease 2019 (COVID-19) vaccine candidate, which, claim the researchers, may be less likely to produce reactions like fevers. It may also have increased protective potential against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen that causes COVID-19.

9 Mar 2021

Rapid increase of UK SARS-CoV-2 variant found in sewage in England between October 2020 to January 2021

A new study confirms the utility of wastewater surveillance as an important new tool in this regard by showing the presence of the UK SARS-CoV-2 variant in wastewater samples from London early in November, with increasing frequency thereafter.

9 Mar 2021

New technique helps image biological samples at the microscopic level

Researchers have developed a spectroscopic microscope to enable optical measurements of molecular conformations and orientations in biological samples. The novel measurement technique allows researchers to image biological samples at the microscopic level more quickly and accurately.

9 Mar 2021

New biosensor measures extracellular hydrogen peroxide levels with nanometer-resolution

Several processes in the human body are regulated by biochemical reactions involving hydrogen peroxide (H2O2).

8 Mar 2021

Inflammation linked to intensity of tobacco smoking among HIV-positive people

Inflammation in the body has been linked to the intensity of tobacco smoking among people with HIV, according to a team of University of Massachusetts Amherst researchers.

8 Mar 2021

Outdoor activities help improve mental health and well-being of teenagers during the pandemic

A study from North Carolina State University found outdoor play and nature-based activities helped buffer some of the negative mental health impacts of the COVID-19 pandemic for adolescents.

8 Mar 2021

On vacci-dating: Singles seem enamored of sharing vaccination status online. Is that wise?

As cold weather descended upon Washington, D.C., last fall, I deleted my dating apps.

8 Mar 2021

Novel bioinformatics tool could help improve COVID-19 diagnosis

An interesting new study by researchers at the University of Liverpool, University of Bristol and Public Health England in the UK describes a novel bioinformatics tool used to detect subgenomic messenger ribonucleic acid (mRNA) sequences from the virus. This may help develop new diagnostic tools and model the transmission of the virus.

8 Mar 2021

How can physicians distinguish between COVID-19 persistence and SARS-CoV-2 reinfection?

One of the most challenging tasks of physicians has been differentiating between persistent COVID-19 and SARS-CoV-2 reinfection. Recently, a team of researchers analyzed SARS-CoV-2 sequences from the publicly available reports on reinfection and persistence. They further characterized the markers of reinfecting sequences and studied the mutation rate in newly evolved persistent variants.

8 Mar 2021

Study confirms B.1.1.7 variant of SARS-CoV-2 is more transmissible

A new modeling study published in the journal Science estimates the B.1.1.7 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant is 43% to 90% more transmissible than previous coronavirus variants. The variant was initially found in Southeast England last fall.

7 Mar 2021

One dose of SARS-CoV-2 vaccine candidate boosts neutralizing antibody response in COVID-19 convalescents

A new study details the results from a single dose of the FINLAY FR 1A recombinant dimeric receptor-binding domain (RBD) base vaccine during a phase I clinical trial with 30 COVID-19 convalescents to test its capacity for boosting natural immunity.

5 Mar 2021

Researchers decipher how interspecies interactions arise, evolve and are maintained

Interspecies interactions are the foundation of ecosystems, from soil to ocean to the human gut. Among the many different types of interactions, syntrophy is a particularly important and mutually beneficial interspecies interaction where one partner provides a chemical or nutrient that is consumed by the other in exchange for a reward.

5 Mar 2021

Frequency News and Research

Research demonstrates multivalent nanobodies overcome SARS-CoV-2 variant mutations

Study: COVID-19 test package can reduce infections and mortality at justifiable cost

Analysis shows moderate evidence for SARS-CoV-2 recombination

2% of individuals carry 90% of SARS-CoV-2 virions: Study of 72,500 tests

SARS-CoV-2 variants rapidly arise in non-human hosts, potential risk for human reinfection

Somatic gene mutations in brain cells could contribute to schizophrenia pathology

Sugar-sweetened soda intake associated with increased risk of mortality among breast cancer patients

A genetic variant of TMPRSS2 may confer protection against severe COVID-19

Optimized SARS-CoV-2 vaccine candidate could be less reactogenic, say researchers

Rapid increase of UK SARS-CoV-2 variant found in sewage in England between October 2020 to January 2021

New technique helps image biological samples at the microscopic level

New biosensor measures extracellular hydrogen peroxide levels with nanometer-resolution

Inflammation linked to intensity of tobacco smoking among HIV-positive people

Outdoor activities help improve mental health and well-being of teenagers during the pandemic

On vacci-dating: Singles seem enamored of sharing vaccination status online. Is that wise?

Novel bioinformatics tool could help improve COVID-19 diagnosis

How can physicians distinguish between COVID-19 persistence and SARS-CoV-2 reinfection?

Study confirms B.1.1.7 variant of SARS-CoV-2 is more transmissible

One dose of SARS-CoV-2 vaccine candidate boosts neutralizing antibody response in COVID-19 convalescents

Researchers decipher how interspecies interactions arise, evolve and are maintained

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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