Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Administering specialized lipids prevents memory loss, inflammation in Down syndrome mouse model

Individuals with Down syndrome are at a much greater risk of developing Alzheimer's disease, with inflammation of the brain starting early in life and the risk of Alzheimer's reaching nearly 80% by the age of 60.

13 Mar 2020

Characterization of DNAm status of MMPs and TIMPs in atheromatous plaques

Oncotarget Volume 11, Issue 10 reported that the statistically associated Cp G sites were analyzed in blood samples from two separate atherothrombotic stroke cohorts, ischemic stroke-cohort 1: 37 atherothrombotic patients and 6 controls, ischemic stroke-cohort 2: 80 atherothrombotic patients and 184 controls.

13 Mar 2020

Post-diagnosis disparities drive worse outcomes for Black and Hispanic children with brain cancer

Cancer researchers have known for years that Black and Hispanic patients have worse outcomes than their non-Hispanic White peers.

12 Mar 2020

No evidence of a link between surgery with anesthesia and Alzheimer's disease

Older adults who have surgery with general anesthesia may experience a modest acceleration of cognitive decline, even years later. But there's no evidence of a link to Alzheimer's disease, according to new research from Mayo Clinic.

12 Mar 2020

AI taps human knowledge for faster and more accurate cancer diagnosis

A new system combining artificial intelligence with human knowledge promises faster and more accurate cancer diagnosis.

11 Mar 2020

Exploiting careless cancer cells to develop new drugs

Could the ability of cancer cells to quickly alter their genome be used as a weapon against malignant tumors? Researchers at Uppsala University have succeeded in developing a substance that has demonstrated promising results in experiments on both animal models and human cancer cells.

11 Mar 2020

Australia: Coronavirus spreads, drive-through testing, pop up clinics and $2.4 billion

Australia has seen an increase in coronavirus disease (COVID-19) cases, and this will continue for weeks despite strict border control measures, experts say. With 116 confirmed cases and thousands of people waiting to be tested, Australian hospitals could be overwhelmed by thousands of patients.

10 Mar 2020

A seismic view of the brain

A new study published in the journal Digital Medicine in March 2020 reports a prototype or pilot study that could make it easier to develop much more accurate imaging technology for the human brain, far more superior to any existing technology such as CT, MRI, and PET scanning.

8 Mar 2020

New discovery could lead to better strategies for preventing breast cancer metastasis

New discovery in breast cancer could lead to better strategies for preventing the spread of cancer cells to other organs in the body, effectively reducing mortality in breast cancer patients.

8 Mar 2020

Gut bacteria can boost effectiveness of cancer immunotherapy, mice study suggests

Could the response to cancer immunotherapy depend on bacteria that originate in the gut and travel to the tumor?

7 Mar 2020

New technique helps study peptide-receptor interactions on the cell surface

In the past, biologically-active peptides - small proteins like neurotoxins and hormones that act on cell receptors to alter physiology - were purified from native sources like venoms and then panels of variants were produced in bacteria, or synthesized, to study the structural basis for receptor interaction.

5 Mar 2020

New experimental platform for cancer diagnostics, prognoses and testing drugs

Parts of tumor tissue, which is normally discarded in cancer surgery, bear information about the disease. So far, as studies at the University of Gothenburg show, this has been unexploited.

4 Mar 2020

Study: Bereaved individuals face higher risk of dying from melanoma

Individuals who experience the loss of a partner are less likely to be diagnosed with melanoma but face an increased risk of dying from the disease, according to research published in the British Journal of Dermatology.

4 Mar 2020

UAB research reveals hydrogen sulfide as new culprit for deadly tuberculosis

A new culprit -- hydrogen sulfide -- has been found for the deadly infectious disease tuberculosis. Hydrogen sulfide gas is known for its rotten egg smell, yet it has normal physiological roles in the human body to communicate among cells.

3 Mar 2020

Obesity could increase severity of influenza study shows

A new study has revealed that those who are obese or overweight tend to get more severe bouts of influenza than those who are a healthy weight. The reason behind this could be the altered immune system of those who are obese. The study outlining this finding is published in the latest issue of the journal mBio from the American Society for Microbiology (ASM). The study was titled, "Obesity-Related Microenvironment Promotes Emergence of Virulent Influenza Virus Strains."

3 Mar 2020

Subpopulations of leukemic cells present at diagnosis can cause relapse in children with ALL

Scientists at St. Jude Children's Research Hospital and Princess Margaret Cancer Centre in Toronto, Canada, have reported that subpopulations of leukemic cells present at diagnosis can cause relapse in children with acute lymphoblastic leukemia.

3 Mar 2020

New method maps 3D forces exerted by tiny cell clusters

A team of researchers has developed a new technique to map the three-dimensional forces that clusters of human cells exert on their surrounding environment. The method could potentially help scientists better understand how tissue forms, how wounds heal or how tumors spread.

3 Mar 2020

Alzheimer's could be detected early using a blood test

Researchers from the ARTFL-LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) research consortium, have reported that a blood test could soon be an important diagnostic tool in detecting the abnormal proteins deposits in the brain that lead to the progressive and debilitating condition of Alzheimer's disease. The study titled, "Diagnostic value of plasma phosphorylated tau181 in Alzheimer's disease and frontotemporal lobar degeneration," was published in today's issue of the journal Nature Medicine.

2 Mar 2020

Study reports advance in blood test to detect accumulation of Alzheimer's protein in the brain

Researchers report an advance in the development of a blood test that could help detect pathological Alzheimer's disease in people who are showing signs of dementia.

2 Mar 2020