Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Skin samples hold early signs of prion disease, research suggests

Prions can infect both humans and animals, causing Creutzfeldt-Jakob disease in humans, mad cow disease in cattle, and chronic wasting disease in elk and deer. The infectious, misfolded protein particles often go undetected as they destroy brain tissue, causing memory loss, mobility issues, and ultimately death.

23 Jan 2019

Insilico to present latest findings in AI for Drug Discovery at 3rd Annual SABPA FTD Forum

Insilico Medicine, a Rockville-based company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, will present its latest results in modern and next-generation AI for Drug Discovery at the 3rd Annual SABPA FTD Forum in San Diego, California, 2 of February.

23 Jan 2019

Scientists have reversed memory loss in a mouse model of Alzheimer’s Disease

Using a new epigenetics-based approach, scientists have managed to reduce memory loss and improve cognitive function in a mouse model of Alzheimer’s disease.

22 Jan 2019

Scientists find bacterial extracellular vesicles in human blood

Belgian scientists have come to the surprising finding that vesicles coming from gut bacteria, are present in blood of patients with HIV, inflammatory bowel disease and cancer.

22 Jan 2019

Blood marker could aid in early prediction of Alzheimer's progression

Years before symptoms of Alzheimer's disease manifest, the brain starts changing and neurons are slowly degraded. Scientists at the German Center for Neurodegenerative Diseases, the Hertie Institute for Clinical Brain Research and the University Hospital Tuebingen now show that a protein found in the blood can be used to precisely monitor disease progression long before first clinical signs appear.

21 Jan 2019

Simple blood test reliably detects signs of Alzheimer’s damage before symptoms

A simple blood test reliably detects signs of brain damage in people on the path to developing Alzheimer's disease - even before they show signs of confusion and memory loss, according to a new study from Washington University School of Medicine in St. Louis and the German Center for Neurodegenerative Diseases in Germany.

21 Jan 2019

Unexpected connection found between feeding and memory centers of the brain

The search for a mechanism that could explain how the protein complex NCOR1/2 regulates memory has revealed an unexpected connection between the lateral hypothalamus and the hippocampus, the feeding and the memory centers of the brain, respectively.

21 Jan 2019

Blood test detects brain damage linked to Alzheimer’s years before symptoms develop

Researchers have developed a blood test that can detect signs of brain damage among people who will develop Alzheimer’s years before the onset of memory loss.

21 Jan 2019

Antiepileptic drug use by people with Alzheimer's disease linked to accumulation of hospital days

People with Alzheimer's disease who used antiepileptic drugs had a higher number of accumulated hospital days than people with Alzheimer's disease who did not use antiepileptics, according to a new study from the University of Eastern Finland.

21 Jan 2019

Signs of memory loss could point to hearing issues

Older adults concerned about displaying early symptoms of Alzheimer's disease should also consider a hearing check-up, suggest recent findings.

21 Jan 2019

MPFI researchers identify synaptic logic for connections between two brain hemispheres

Researchers at the Max Planck Florida Institute for Neuroscience have developed a new combination of technologies that allows them to identify the functional properties of individual synapses that link the two hemispheres and determine how they are arranged within a neuron's dendritic field.

21 Jan 2019

Scientists reveal new mechanism that could lead to specific treatment of strokes and seizures

The ideal drug is one that only affects the exact cells and neurons it is designed to treat, without unwanted side effects.

21 Jan 2019

Researchers get close to developing elusive blood test for Alzheimer's disease

People with symptoms of Alzheimer's disease, such as cognitive difficulties, behavior changes and mood swings, may wait months or even years to get a definitive diagnosis. That's because doctors lack a simple, accurate and inexpensive test for it.

18 Jan 2019

Scientists design two AI algorithms to improve early detection of cognitive impairment

Researchers of the Pharmacy and Mathematics departments of the CEU UCH university in Valencia have collaborated in the design of two artificial intelligence algorithms that improve the screening of positive cases in the early detection of cognitive impairment in chemists.

17 Jan 2019

Blood vessels can now be created perfectly in a petri dish

Researchers have now successfully created perfect blood vessels in the labs and this may be a huge step in benefitting people with diabetes and other conditions. The report of the procedure appears in a study titled, “Human blood vessel organoids as a model of diabetic vasculopathy,” published in the latest issue of the journal Nature.

17 Jan 2019

Research brings new hope to treating degenerative brain diseases

Alzheimer's disease is the most representative degenerative brain disease, accounting for 60 to 80% of all dementia cases. In search for new mechanism for AD, the research team led by Professor Seong-Woon Yu of Brain and Cognitive Sciences paid attention to the autophagy of microglia, brain immune cells, is suppressed by inflammation.

17 Jan 2019

The cytoskeleton of neurons found to play role in Alzheimer's disease

A researcher at the UPV/EHU has participated in a study describing what it is during the early stages of Alzheimer's that triggers the loss of dynamics and subsequent impairment of the dendritic spines, the compartments of the neurons responsible for receiving nerve impulses from other neurons.

17 Jan 2019

Improvements in pharmacological study to fight cognitive impairment in schizophrenia

A study by the UPV/EHU has assessed the effectiveness of various drugs, which are used to delay cognitive deterioration in patients with Alzheimer's, in improving cognitive impairment displayed by patients with schizophrenia.

17 Jan 2019

Smoking significantly increases your biological age, study shows

Insilico Medicine, one of the leaders in artificial intelligence for drug discovery, biomarker development, digital medicine, and aging research, announced the publication of a new collaborative research paper titled "Blood Biochemistry Analysis to Detect Smoking Status and Quantify Accelerated Aging in Smokers" in Scientific Reports.

17 Jan 2019

Mutant mice administered with cocaine failed to exhibit hyperactivity, shows study

Cocaine is a highly addictive psychostimulant that induces complex molecular, cellular and behavioral responses. Despite various approaches and years of pre-clinical studies, effective, mechanism-based therapies to assist with cocaine misuse and dependence are still sorely lacking.

16 Jan 2019

Alzheimer's Disease News and Research

Further Reading

Skin samples hold early signs of prion disease, research suggests

Insilico to present latest findings in AI for Drug Discovery at 3rd Annual SABPA FTD Forum

Scientists have reversed memory loss in a mouse model of Alzheimer’s Disease

Scientists find bacterial extracellular vesicles in human blood

Blood marker could aid in early prediction of Alzheimer's progression

Simple blood test reliably detects signs of Alzheimer’s damage before symptoms

Unexpected connection found between feeding and memory centers of the brain

Blood test detects brain damage linked to Alzheimer’s years before symptoms develop

Antiepileptic drug use by people with Alzheimer's disease linked to accumulation of hospital days

Signs of memory loss could point to hearing issues

MPFI researchers identify synaptic logic for connections between two brain hemispheres

Scientists reveal new mechanism that could lead to specific treatment of strokes and seizures

Researchers get close to developing elusive blood test for Alzheimer's disease

Scientists design two AI algorithms to improve early detection of cognitive impairment

Blood vessels can now be created perfectly in a petri dish

Research brings new hope to treating degenerative brain diseases

The cytoskeleton of neurons found to play role in Alzheimer's disease

Improvements in pharmacological study to fight cognitive impairment in schizophrenia

Smoking significantly increases your biological age, study shows

Mutant mice administered with cocaine failed to exhibit hyperactivity, shows study

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