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CeMM scientists develop new method by integrating CRISPR genome editing with single-cell sequencing

Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets.

19 Jan 2017

Blocking molecular signaling pathway could prevent or reverse peripheral neuropathy

Researchers at University of California San Diego School of Medicine, with colleagues at the National Institute of Diabetes and Digestive and Kidney Diseases, the University of Manitoba and St. Boniface Hospital Albrechtsen Research Centre in Canada, have identified a molecular signaling pathway that, when blocked, promotes sensory neuron growth and prevents or reverses peripheral neuropathy in cell and rodent models of type 1 and 2 diabetes, chemotherapy-induced neuropathy and HIV.

18 Jan 2017

Study shows clinical and psychosocial consequences following survival of Ebola infection

The long-term clinical and social sequelae following survival of Ebola infection are unknown.

18 Jan 2017

Researchers test new HIV neutralising antibody in humans

A research team led by investigators of the Rockefeller University in New York and Prof Florian Klein, University Hospital Cologne and German Center for Infection Research, has tested a new HIV neutralising antibody, called 10-1074, in humans.

18 Jan 2017

Researchers discover role of neuron protein in learning abilities and AIDS-related dementia

Researchers from the University of California and Cardiff University have made a breakthrough in the understanding of AIDS-related dementia, discovering the role of a neuron protein which was also found to affect learning abilities in healthy subjects.

18 Jan 2017

Georgia State University, GeoVax join forces to advance development of Hepatitis B therapeutic vaccine

The Georgia State University Research Foundation has entered into a research collaboration agreement with GeoVax Labs, Inc., a Georgia-based biotechnology company developing human vaccines, to advance development of a therapeutic vaccine for treatment of chronic Hepatitis B infections.

18 Jan 2017

Better fungal disease diagnostics could be critical to fight against antimicrobial resistance

Poor diagnosis worldwide of fungal disease causes doctors to overprescribe antibiotics, increasing harmful resistance to antimicrobial drugs, according to a paper published today in Emerging Infectious Diseases.

17 Jan 2017

Antiretroviral drugs may increase gay and bisexual men's susceptibility to syphilis

The antiretroviral drugs used to treat HIV infection might inadvertently be boosting gay/bisexual men's susceptibility to the bacteria responsible for syphilis, Treponema pallidum, conclude researchers in the journal Sexually Transmitted Infections.

17 Jan 2017

MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

Massachusetts General Hospital investigators have identified a protein that may play an essential role in maintaining a population of tumor-initiating cells (TICs) -- treatment-resistant cells responsible for cancer recurrence and metastasis -- in breast cancer, as well as a compound that appears to reduce the molecule's ability to protect TICs from the effects of chemotherapy.

17 Jan 2017

Reducing cocaine use can potentially reverse coronary atherosclerosis

People who use cocaine regularly are at high risk of coronary artery disease. A study in the Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine, reports that stopping or reducing cocaine use can potentially reverse the process of coronary atherosclerosis. The journal is published by Wolters Kluwer.

12 Jan 2017

Endogenous retroviruses may have played significant role in development of the brain

Over millions of years retroviruses have been incorporated into our human DNA, where they today make up almost 10 per cent of the total genome.

12 Jan 2017

Scientists identify Smurf1 protein that plays role in autophagy of TB bacteria

UT Southwestern Medical Center researchers have identified a protein that is central to the immune system's ability to recognize and destroy the bacterium responsible for the global tuberculosis (TB) epidemic.

12 Jan 2017

Could pathogen infection really lead to Alzheimer’s?

New concepts of infectious disease are evolving with the realization that pathogens are key players in the development of progressive chronic diseases that originally were not thought to be infectious. Infection is well-known to be associated with numerous neurological diseases for which...

12 Jan 2017

Penn Vet researchers identify potential target to fight against Ebola

Viruses and their hosts are in a eternal game of one-upmanship. If a host cell evolves a way to stop a virus from spreading, the virus will look for a new path. And so on and so forth.

12 Jan 2017

Research findings could lead to development of novel therapeutic approaches against viral infections

Life is a question of balance, and the body is no exception. Expression levels of certain proteins can affect the immune system's ability to neutralize a virus.

12 Jan 2017

CDC guidelines for PrEP use to prevent HIV transmission do not go far enough, UCLA study suggests

A new study from the UCLA Fielding School of Public Health suggests modifying federal health guidelines related to the use of pre-exposure prophylaxis to prevent HIV transmission because current standards could miss some people who should be on it.

12 Jan 2017

Researchers identify sub-population of HIV-1 strains with biological properties to transmit new infections

Upon sexual exposure, the AIDS virus must overcome some mighty barriers to find the right target cell and establish a new infection.

11 Jan 2017

MGH researchers identify gene mutations linked to rare congenital condition involving lack of nose

Researchers from Massachusetts General Hospital led a large, international research team that has identified gene mutations associated with a rare congenital condition involving the absence of a nose and often accompanied by defects involving the eye and reproductive systems.

11 Jan 2017

Penn State researchers develop novel compound to combat cytomegalovirus

A Retro94-based compound may prevent a common and sometimes fatal virus -- human cytomegalovirus (CMV) -- from reproducing and help to protect immunocompromised patients, such as those with HIV, on chemotherapy, with transplants, and infants from the effects of the disease, according to Penn State College of Medicine researchers.

10 Jan 2017

Retroviruses almost several hundred million years older than previously thought

Retroviruses - the family of viruses that includes HIV - are almost half a billion years old, according to new research by scientists at Oxford University.

10 Jan 2017

HIV News and Research

CeMM scientists develop new method by integrating CRISPR genome editing with single-cell sequencing

Blocking molecular signaling pathway could prevent or reverse peripheral neuropathy

Study shows clinical and psychosocial consequences following survival of Ebola infection

Researchers test new HIV neutralising antibody in humans

Researchers discover role of neuron protein in learning abilities and AIDS-related dementia

Georgia State University, GeoVax join forces to advance development of Hepatitis B therapeutic vaccine

Better fungal disease diagnostics could be critical to fight against antimicrobial resistance

Antiretroviral drugs may increase gay and bisexual men's susceptibility to syphilis

MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

Reducing cocaine use can potentially reverse coronary atherosclerosis

Endogenous retroviruses may have played significant role in development of the brain

Scientists identify Smurf1 protein that plays role in autophagy of TB bacteria

Could pathogen infection really lead to Alzheimer’s?

Penn Vet researchers identify potential target to fight against Ebola

Research findings could lead to development of novel therapeutic approaches against viral infections

CDC guidelines for PrEP use to prevent HIV transmission do not go far enough, UCLA study suggests

Researchers identify sub-population of HIV-1 strains with biological properties to transmit new infections

MGH researchers identify gene mutations linked to rare congenital condition involving lack of nose

Penn State researchers develop novel compound to combat cytomegalovirus

Retroviruses almost several hundred million years older than previously thought

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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