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Two proteins work in tandem to build lifelines to cancer cells, study finds

In human cancer cell and mouse studies, researchers from Johns Hopkins Medicine have found that a set of proteins work in tandem to build supply lines that deliver oxygen and nutrients to tumors, enabling them to survive and grow.

20 Sep 2021

Specially designed lipid nanoparticles overcome resistance to anti-tumor immunotherapy

A specially designed lipid nanoparticle could deliver immune-signaling molecules into liver macrophage cells to overcome resistance to anti-tumor immunotherapy.

18 Sep 2021

Scientists identify new approach to overcome resistance to cancer immunotherapy

Hokkaido University scientists and colleagues in Japan have found a way that could help some patients overcome resistance to immunotherapy treatment for cancer. The approach, proven in mice experiments, was reported in the Journal for Immunotherapy of Cancer.

17 Sep 2021

Owlstone Medical appoints Mark Capone to board of directors

Owlstone Medical, the global leader in Breath Biopsy® for applications in early disease detection and precision medicine, today announced the appointment of Mark Capone, former President and CEO of Myriad Genetics to its Board as an independent non-executive director.

From Owlstone Medical Ltd 17 Sep 2021

New vaccine platform can better induce anti-malaria immunity in the liver

Malaria remains a deadly disease that affects people worldwide, particularly in Africa. Caused by a parasite that can enter the human bloodstream via mosquito bite, the parasites can then infect and reproduce within the person's liver.

16 Sep 2021

Antiviral compound RG10 acts via intracellular SARS-CoV-2-ER dynamics

A new study describes a small molecule referred to as RG10 that may have potent antiviral activity against SARS-CoV-2 in human cells.

16 Sep 2021

When covid deaths are dismissed or stigmatized, grief is mixed with shame and anger

Months after Kyle Dixon died, his old house in Lanse, Pennsylvania, is full of reminders of a life cut short.

16 Sep 2021

Study identifies probable cause of Alzheimer’s disease

Ground-breaking new Curtin University-led research has discovered a likely cause of Alzheimer's disease, in a significant finding that offers potential new prevention and treatment opportunities for Australia's second-leading cause of death.

16 Sep 2021

Grants to promote COVID-19 vaccination among people with intellectual and developmental disabilities

Patients with intellectual and developmental disabilities (IDD) are three times more likely to die from COVID-19 than the general population. Their heightened risk is due to a variety of causes: pre-existing health conditions, such as respiratory problems or obesity; increased likelihood of living in group homes, taking shared transportation, and being exposed to people outside their households; and struggles with safety precautions like mask-wearing or social distancing.

16 Sep 2021

Study discovers biological mechanism linking long-term arsenic exposure to cancer, diabetes

A University of Arizona Health Sciences study has identified the biological mechanism linking long-term arsenic exposure to diseases such as cancer and Type 2 diabetes.

15 Sep 2021

Albert Einstein College of Medicine receives $5 million NIH grant for IDD research

Albert Einstein College of Medicine has received a five-year, $5 million grant from the National Institutes of Health to support the Rose F. Kennedy Intellectual and Developmental Disabilities Research Center, which has been at the forefront of research on normal and abnormal brain development for more than 50 years.

15 Sep 2021

Liver may play a key role in the onset or progression of Alzheimer's disease

Amyloid protein made in the liver can cause neurodegeneration in the brain, according to a new study in the open-access journal PLOS Biology, by John Mamo of Curtin University in Bentley, Australia, and colleagues.

14 Sep 2021

Researchers explore whether cocoa supplementation can reduce aging

Whether consuming cocoa, known to be packed with powerful antioxidants that protect our cells from damage, helps us age better, is a question scientists want to definitively answer.

14 Sep 2021

mRNA BNT162b2 vaccine safe in immunocompromised patients

The clinical trial showed that about 72.2% of immunocompromised patients had detectable antibodies against SARS-CoV-2.

14 Sep 2021

IU researcher uncovers potential new approach for treating pancreatic cancer

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have identified how restoring a missing molecule in pancreatic fibrosis could help deliver treatments to cancer cells.

14 Sep 2021

New method for profiling tissue-specific secretory proteins in live mice

Researchers have presented a method for profiling tissue-specific secretory proteins in live mice. This method is expected to be applicable to various tissues or disease models for investigating biomarkers or therapeutic targets involved in disease progression.

14 Sep 2021

Metabolic and immune markers as tools for risk stratification and monitoring in COVID-19

In a new study posted to the medRxiv* server scientists from Weil Cornell University and Stony Brook University in New York attempted to identify the metabolic and immune markers associated with severe COVID-19 disease using high-throughput targeted nuclear magnetic resonance (NMR) spectroscopy and high-dimensional flow cytometry. This will facilitate risk stratification, monitoring, and therapeutic interventions in COVID-19 patients.

14 Sep 2021

Experimental device offers glycemic control to hyperinsulinism patients after pancreatectomy

Researchers at Children's Hospital of Philadelphia have demonstrated that an experimental device can improve blood sugar control in patients who developed diabetes after their pancreas was removed to treat their hyperinsulinism, a genetic disease in which the pancreas produces too much insulin.

13 Sep 2021

Pharmacotherapy for alcohol use disorder is underutilized in Sweden, finds study

Only a minority of Swedes with alcohol use disorders are prescribed alcohol medication, a situation that has remained largely unchanged in the country since the mid-2000.

13 Sep 2021

New online tool to predict mortality risk for patients with acute-on-chronic liver failure

For patients with chronic liver disease, the onset of acute-on-chronic liver failure (ACLF) instantly alters the transplant question from 'if' to 'when'. 60 to 70% of patients with ACLF die within 3 months due to poor liver function and multiple organ failure.

13 Sep 2021

Liver News and Research

Two proteins work in tandem to build lifelines to cancer cells, study finds

Specially designed lipid nanoparticles overcome resistance to anti-tumor immunotherapy

Scientists identify new approach to overcome resistance to cancer immunotherapy

Owlstone Medical appoints Mark Capone to board of directors

New vaccine platform can better induce anti-malaria immunity in the liver

Antiviral compound RG10 acts via intracellular SARS-CoV-2-ER dynamics

When covid deaths are dismissed or stigmatized, grief is mixed with shame and anger

Study identifies probable cause of Alzheimer’s disease

Grants to promote COVID-19 vaccination among people with intellectual and developmental disabilities

Study discovers biological mechanism linking long-term arsenic exposure to cancer, diabetes

Albert Einstein College of Medicine receives $5 million NIH grant for IDD research

Liver may play a key role in the onset or progression of Alzheimer's disease

Researchers explore whether cocoa supplementation can reduce aging

mRNA BNT162b2 vaccine safe in immunocompromised patients

IU researcher uncovers potential new approach for treating pancreatic cancer

New method for profiling tissue-specific secretory proteins in live mice

Metabolic and immune markers as tools for risk stratification and monitoring in COVID-19

Experimental device offers glycemic control to hyperinsulinism patients after pancreatectomy

Pharmacotherapy for alcohol use disorder is underutilized in Sweden, finds study

New online tool to predict mortality risk for patients with acute-on-chronic liver failure

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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