Genetic News and Research

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Better understanding of cancer cachexia

New research shows that a wasting condition responsible for nearly a third of all cancer deaths involves the loss of an essential muscle protein that is also lost in people with muscular dystrophy.

15 Nov 2005

Gene therapy and exercise may help sufferers of Lou Gehrig's disease

A new study in mice gives hope that a combination of gene therapy and exercise may extend the lives of people who have Lou Gehrig's disease.

15 Nov 2005

Olfactory epithelium plays a critical role in pheromone detection

Howard Hughes Medical Institute researchers have discovered that pheromones essential for mating behavior in mice are recognized by the nose and not by the vomeronasal system, as researchers had long suspected.

14 Nov 2005

Australian study highlights lateral genetic transfer

A University of Queensland study mapping the evolution of genes has shed light on the role of gene transfer in bacterial diseases.

14 Nov 2005

Positive aspects of bipolar disorder

Researchers at the Stanford University School of Medicine have shown for the first time that a sample of children who either have or are at high risk for bipolar disorder score higher on a creativity index than healthy children.

14 Nov 2005

How parents treat their children can affect an adolescent's risk of depression

How parents treat their adolescent children, including the way they discipline them, as well as the kind of life events and social interactions teenagers experience, can affect an adolescent's risk of depression, regardless of any genetic predisposition towards the mental illness.

14 Nov 2005

Discovery of novel form of regulation of the GLI1 gene

The Quaking gene, first described as a mutation in mice that causes rapid tremor, is thought to suppress tumor formation and protect humans from cancer.

14 Nov 2005

First step in exploring the GnRH reproduction-related circuitry in the brain

Howard Hughes Medical Institute researchers have discovered a vast network of neurons in the brain of mice that governs reproduction and controls the effects of reproductive status on other brain functions.

14 Nov 2005

Researchers can now identify patients likely to respond to cancer drug therapy

Researchers at UCLA's Jonsson Cancer have identified key characteristics in certain deadly brain tumors that make them 51 times more likely to respond to a specific class of drugs than tumors in which the molecular signature is absent.

13 Nov 2005

Loneliness may be heredity

Heredity helps determine why some adults are persistently lonely, research co-authored by psychologists at the University of Chicago shows.

13 Nov 2005

New understanding of the disease process involved in atherosclerosis

The progression of the artery-clogging disease atherosclerosis is linked to the inability of specialized bone marrow cells to continuously repair damage to the arterial lining, Duke University Medical Center researchers have demonstrated.

13 Nov 2005

Link between diet and epileptic seizures studied

Although the high-fat, calorie-restricted ketogenic diet (KD) has long been used to prevent childhood epileptic seizures that are unresponsive to drugs, physicians have not really understood exactly why the diet works.

13 Nov 2005

Lifelong exercise decreases cellular aging in the brain

In the first study to show that lifelong exercise decreases cellular aging in the brain, scientists from the McKnight Brain Institute of the University of Florida say that moderately active rats have healthier DNA and more robust brain cells than their less active counterparts. The research was presented at the Society for Neuroscience's 35th annual meeting in Washington, D.C.

13 Nov 2005

Genetic factors versus environmental factors in assessing malaria risk

Humans exposed to malaria get infected and sick to varying degrees, and some of that variation is due to differences in genetic makeup between individuals. But how important are genetic factors compared with environmental ones?

13 Nov 2005

Cellular signal may determine life or death for damaged brain cells

Scientists at the Universities of Heidelberg and Ulm and a unit of the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, have discovered that a specific signal within brain cells may determine whether they live or die after a stroke.

13 Nov 2005

Another bird flu death as $1 billion plan revealed to fight virus

The announcement by Health experts of a $1 billion plan to halt the spread of bird flu came at the same time as Indonesia said initial tests showed the virus had killed a 16-year-old girl.

9 Nov 2005

Aspirin and ibuprofen may significantly reduce the risk of esophageal cancer among people with Barrett's esophagus

Aspirin and other nonsteroidal anti- inflammatory drugs, such as ibuprofen, may significantly reduce the risk of esophageal cancer among people with Barrett's esophagus, a precancerous condition associated with chronic heartburn that affects an estimated 1 million to 2 million Americans.

8 Nov 2005

Introgen's INGN 241 combined with Celebrex kills breast cancer cells

Introgen Therapeutics, Inc. today reported the publication of preclinical data demonstrating that INGN 241 works synergistically with celecoxib (Celebrex) marketed by Pfizer to inhibit the growth and increase apoptosis (cell death) of breast cancer cells.

8 Nov 2005

LGC licenses first DNA test for response to schizophrenia treatment from the Institute of Psychiatry, King’s College London

LGC, Europe's leading independent analytical laboratory providing advanced chemical, biochemical and forensic analysis, has announced an exclusive agreement with King’s College London to offer the first pharmacogenetic screening service which will predict whether a patient with schizophrenia will respond positively to the antipsychotic drug clozapine.

8 Nov 2005

Statin drug reverses learning and attention deficits in a mouse model of the genetic disorder Neurofibromatosis type I

This week, researchers report evidence that a statin drug already shown to be safe for use in humans has proven effective at correcting cell-cell communication and curing learning disfunction in a mouse model of Neurofibromatosis type I, a human genetic disorder that causes learning disabilities in millions of people worldwide.

7 Nov 2005