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SARS-CoV-1 utilizes ORF3a protein to trigger viral release

Scientists in the USA – from the Johns Hopkins University and the University of Maryland – have recently uncovered the mechanism by which SARS-CoV-1 is released from the infected cells.

21 Apr 2021

SARS-CoV-2 pandemic underscores importance of understanding evolution of RNA genomes

The current COVID-19 (coronavirus disease 2019) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), underscores the importance of understanding the evolution of ribonucleic acid (RNA) genomes.

21 Apr 2021

Comprehensive roadmap of muscle aging reveals potential targets for treatments

Scientists have produced a comprehensive roadmap of muscle aging in mice that could be used to find treatments that prevent decline in muscle mobility and function, according to a report published today in eLife.

20 Apr 2021

Can an immunosuppressive cancer drug promote SARS-CoV-2 entry into host cells?

A new study shows that rapamycin, an immunosuppressive drug used in some cancers, and its analogs, may have an undesirable effect on viral entry into the host cells. This finding could inform their use to treat symptomatic COVID-19.

20 Apr 2021

Scientists receive NIH grant to develop an adjuvant vaccine for opioid use disorder

Opioid addicts wage a daily war within over whether or not to use a drug whose side effect can be death. If those same addicts, however, had the choice to take an opioid vaccine once or twice a year, their internal struggle could be over.

20 Apr 2021

K162 molecule could inhibit β-amyloids ' toxicity associated with Alzheimer's disease

Alzheimer's disease (AD) is a form of progressive dementia interfering with daily living. It is caused by the decline in the number of brain cells resulting in the deterioration of our mental abilities.

20 Apr 2021

Use of ozone as a decontaminant for SARS-CoV-2

Researchers in Germany have demonstrated how an ozone-based decontamination device significantly reduces the volume of viral residue left on surfaces of two surrogate viruses for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

20 Apr 2021

Research team identifies new factor in the development of psoriasis

Psoriasis is a common inflammatory skin condition. The underlying genetic factors have not yet been sufficiently researched.

19 Apr 2021

Mirati to contribute $4 million grant to support SU2C research on KRAS mutant cancers

Stand Up To Cancer and Mirati Therapeutics Inc. - a late-stage targeted oncology company - today announced that Mirati will contribute a $4 million grant to SU2C to develop new approaches to treat patients with KRAS mutant cancers, as a part of the SU2C Catalyst program.

19 Apr 2021

Plant-derived compound isorhamnetin may have antiviral potential against SARS-CoV-2

The lack of new or repurposed drugs to treat patients with severe or critical COVID-19 has been one of the biggest hurdles to reducing mortality rates in the ongoing pandemic caused by SARS-CoV-2. A new study describes the potential for the use of the plant molecule isorhamnetin in the management of this virus.

19 Apr 2021

SARS-CoV-2 nucleoprotein can trigger α-synuclein amyloid fibril formation

A new study, released as a preprint on the bioRxiv* server, casts some light on the pathogenesis of acute and subacute neurological complications associated with COVID-19.

19 Apr 2021

New study sheds light on complex brain process that helps learn and form new memories

Making memories involves more than seeing friends or taking photos. The brain constantly adapts to new information and stores memories by building connections among neurons, called synapses. How neurons do this--reaching out arm-like dendrites to communicate with other neurons--requires a ballet of genes, signaling molecules, cellular scaffolding and protein-building machinery.

19 Apr 2021

Study sheds light on how tau aggregates promote Alzheimer’s disease

Look deep inside the brain of someone with Alzheimer's disease, most forms of dementia or the concussion-related syndrome known as chronic traumatic encephalopathy (CTE) and you'll find a common suspected culprit: stringy, hairball-like tangles of a protein called tau.

17 Apr 2021

Numerous agents with anti-SARS-CoV-2 potential discovered with crystallographic screening

An international team of researchers focused on the macrodomain part of the non-structural protein 3 (Nsp3) gene product that SARS-CoV-2 uses to overturn the host cell’s natural antiviral response. The team provided a template that can help develop novel antivirals that are direct-acting and can combat the current pandemic.

16 Apr 2021

COVID-19 vaccination of lactating mothers elicits specific IgA antibodies in breast milk

A new study, released on the medRxiv* preprint server, examines the presence of SARS-CoV-2-specific IgA in human milk and its association with the protection of breastfed infants against the disease.

16 Apr 2021

Curcumin nanosystems could be powerful COVID-19 therapeutics

With new variants of SARS-CoV-2 emerging, the COVID-19 pandemic is far from over. While the global vaccine rollout has moved at an impressive speed, the search for new safe, effective, and targeted therapies is still on. Now, a new study reviews the potential for curcumin, a natural alkaloid derived from turmeric, and nanosystems to treat COVID-19.

16 Apr 2021

HP1a is a key epigenetic regulator that maintains chromosome integrity

The information of the human genome is encoded by approximately 3 billion DNA base pairs and packaged into 23 pairs of chromosomes.

16 Apr 2021

Researchers probe intriguing interaction between sugars and the SARS-CoV-2 spike protein

A new study posted to the bioRxiv preprint server focuses on a novel formulation of magnetization or saturation transfer. This method is developed by amalgamating theoretical and computational approaches based on a Bayesian deconvolution algorithm, which helps obtain data more accurately and determine the ligand-protein interaction.

16 Apr 2021

Novel gene mutations may help identify patients with a specific form of muscular dystrophy

New research from the University of Minnesota Medical School found mutations in a novel gene that may help identify patients with a specific form of muscular dystrophy.

16 Apr 2021

New machine learning method for designing more effective antibody drugs

Antibodies are not only produced by our immune cells to fight viruses and other pathogens in the body. For a few decades now, medicine has also been using antibodies produced by biotechnology as drugs.

15 Apr 2021

Molecule News and Research

SARS-CoV-1 utilizes ORF3a protein to trigger viral release

SARS-CoV-2 pandemic underscores importance of understanding evolution of RNA genomes

Comprehensive roadmap of muscle aging reveals potential targets for treatments

Can an immunosuppressive cancer drug promote SARS-CoV-2 entry into host cells?

Scientists receive NIH grant to develop an adjuvant vaccine for opioid use disorder

K162 molecule could inhibit β-amyloids ' toxicity associated with Alzheimer's disease

Use of ozone as a decontaminant for SARS-CoV-2

Research team identifies new factor in the development of psoriasis

Mirati to contribute $4 million grant to support SU2C research on KRAS mutant cancers

Plant-derived compound isorhamnetin may have antiviral potential against SARS-CoV-2

SARS-CoV-2 nucleoprotein can trigger α-synuclein amyloid fibril formation

New study sheds light on complex brain process that helps learn and form new memories

Study sheds light on how tau aggregates promote Alzheimer’s disease

Numerous agents with anti-SARS-CoV-2 potential discovered with crystallographic screening

COVID-19 vaccination of lactating mothers elicits specific IgA antibodies in breast milk

Curcumin nanosystems could be powerful COVID-19 therapeutics

HP1a is a key epigenetic regulator that maintains chromosome integrity

Researchers probe intriguing interaction between sugars and the SARS-CoV-2 spike protein

Novel gene mutations may help identify patients with a specific form of muscular dystrophy

New machine learning method for designing more effective antibody drugs

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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