Immune System News and Research

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Pancreatic cancer study reveals the cause of tumor cell resistance to immunotherapy

A new study that analyzed the tumor microenvironment of pancreatic cancer revealed the cause of tumor cell resistance to immunotherapy and resulted in new treatment strategies.

26 Jan 2023

Persistent tumor mutation burden linked with therapeutic response to immunotherapy

Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation burden (TMB), to predict a patient's response to immunotherapy.

26 Jan 2023

Researchers discover the impact of microRNA on inflammation in lupus

A group of researchers from the Graduate School of Medicine at Nagoya University in Japan have discovered the impact of microRNA (miRNA) on inflammation in lupus in mice.

26 Jan 2023

Scientists illuminate how blood cancer treatments can lead to therapy-related myeloid neoplasms

Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have illuminated how treatments for multiple myeloma and other aggressive blood cancers can lead to future malignancies, called therapy-related myeloid neoplasms (tMNs).

25 Jan 2023

F-box gene mediates dietary restriction effects on extending the health span of C. elegans

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 1, entitled, "The innate immune signaling component FBXC-58 mediates dietary restriction effects on healthy aging in Caenorhabditis elegans."

25 Jan 2023

Study provides an estimate of people in the United States with VEXAS syndrome

About 13,200 men and another 2,300 women in the United States over age 50 are estimated to have VEXAS syndrome, according to a new study led by researchers at NYU Grossman School of Medicine.

24 Jan 2023

Transient gut infection influences hosts’ adaptation to nutrient restriction

Transient gut infection not only promotes white adipose tissue expansion and host weight gain but also optimizes host metabolism for carbohydrates.

23 Jan 2023

CHLA launches first clinical trial for Down syndrome regression disorder with $5.3 million NIH grant

Children's Hospital Los Angeles has launched the first clinical trial for Down syndrome regression disorder (DSRD), a rare and debilitating condition that affects adolescents and young adults with Down syndrome.

23 Jan 2023

Healthy gene found in centenarians can reverse the decline of heart performance in older people

An anti-aging gene discovered in a population of centenarians has been shown to rewind the heart's biological age by 10 years.

23 Jan 2023

Study reviews mechanistic data on new methods of allergy prevention and treatment

In a recent article published in Science Translational Medicine, researchers reviewed the cause and the underlying pathophysiology of allergic diseases.

23 Jan 2023

Study analyzes how immunological memory gets generated and maintained

Scientists have long sought to better understand the human body's immune responses that occur during various diseases, including cancer and inflammatory diseases.

23 Jan 2023

Advantages and challenges of using interstitial fluid for disease diagnosis, health monitoring

The next frontier of continuous health monitoring could be skin deep.

20 Jan 2023

10 years of CRISPR genome editing: Advances, limitations, and future potential

In the decade since the publication of CRISPR-Cas9 as a genome editing technology, the CRISPR toolbox and its applications have profoundly changed biological research, enabling advances through applications in plants, animals, and humans.

20 Jan 2023

Researchers create the first 'living medicine' to treat drug-resistant lung infections

Researchers have designed the first 'living medicine' to treat lung infections. The treatment targets Pseudomonas aeruginosa, a type of bacteria which is naturally resistant to many types of antibiotics and is a common source of infections in hospitals.

19 Jan 2023

Mutations may underlie how the most aggressive lymphomas arise and resist therapies

The key to understanding how the most aggressive lymphomas arise and resist current therapies may lie in mutations that disrupt a critical natural selection process among antibody-producing B cells, according to a multi-institutional preclinical study led by Weill Cornell Medicine investigators.

19 Jan 2023

Researchers create large-scale 2D and 3D spatial maps of colorectal cancer

In the United States, turning 45 brings with it a rather unpleasant rite of passage: the beginning of regular colonoscopies, in which an endoscope equipped with a light and a camera is used to visually check the colon for signs of cancer.

19 Jan 2023

Understanding the mechanisms involved in heart disease and cancers

In a crucial step towards understanding the mechanisms involved in cardiovascular disease and certain cancers, a Canadian led research team has succeeded in a world first: they've found the molecular mechanism by which the protein PCSK9 degrades the receptor of low density lipoproteins, the richest cholesterol particles in the bloodstream.

19 Jan 2023

Immune System News and Research

Pancreatic cancer study reveals the cause of tumor cell resistance to immunotherapy

Persistent tumor mutation burden linked with therapeutic response to immunotherapy

Researchers discover the impact of microRNA on inflammation in lupus

Scientists illuminate how blood cancer treatments can lead to therapy-related myeloid neoplasms

F-box gene mediates dietary restriction effects on extending the health span of C. elegans

Study provides an estimate of people in the United States with VEXAS syndrome

Transient gut infection influences hosts’ adaptation to nutrient restriction

CHLA launches first clinical trial for Down syndrome regression disorder with $5.3 million NIH grant

Healthy gene found in centenarians can reverse the decline of heart performance in older people

Study reviews mechanistic data on new methods of allergy prevention and treatment

Study analyzes how immunological memory gets generated and maintained

Advantages and challenges of using interstitial fluid for disease diagnosis, health monitoring

10 years of CRISPR genome editing: Advances, limitations, and future potential

Researchers create the first 'living medicine' to treat drug-resistant lung infections

Mutations may underlie how the most aggressive lymphomas arise and resist therapies

Researchers create large-scale 2D and 3D spatial maps of colorectal cancer

Understanding the mechanisms involved in heart disease and cancers

UQ researchers identify a cellular pathway to reprogram the body’s immune system

Immunological interactions between asthma, obesity, and the microbiota

Researchers use single-cell RNA-sequencing to study the aging peripheral blood in mice

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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