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Highly sensitive CRISPR-based method designed to detect low-frequency cancer mutations

Liquid biopsy is increasingly recognized as a promising tool for cancer detection and treatment monitoring, yet its effectiveness is often limited by the extremely low levels of tumor-derived DNA circulating in the blood.

9 Dec 2025

New study reveals productivity losses from substance use disorder in the U.S.

A new study shows that in 2023, substance use disorders led to nearly $93 billion in lost productivity in the United States from missed work, reduced job performance, inability to work, and lost household productivity.

9 Dec 2025

Accuracy of remote photoplethysmography drops sharply at elevated heart rates

Researchers at Bielefeld University have analyzed how reliably AI methods can detect pulse rates from simple video recordings.

9 Dec 2025

High BMI and poor physical fitness in adolescence linked to severe bacterial infections in adulthood

High BMI and poor physical fitness during later adolescence increase the risk of both contracting and dying from sepsis and other severe bacterial infections in adulthood, according to a study from the University of Gothenburg.

9 Dec 2025

Physical activity may help restore ease of movement and agility during aging

The brain-chemical surge that comes with running may bolster coordination and speed in the old and young alike, a new study of middle-aged mice shows.

9 Dec 2025

Online reference library provides a more accurate picture of drug exposure

Doctors and researchers try to understand what medications a person has taken by asking patients directly or by looking at medical records. But this information is often incomplete.

9 Dec 2025

Study reveals how brain protein KCC2 influences reward learning

A new finding from researchers at Georgetown University Medical Center shows that the learning process of associating cues with rewards can be altered by increased or decreased activity of a specific protein in the brain.

9 Dec 2025

A 36-week screening strategy safely reduces pre-eclampsia at term

Screening pregnant women at 36 weeks using a validated risk model and offering risk-stratified planned early-term birth reduced the incidence of term pre-eclampsia by about 30 percent without increasing maternal or neonatal complications. The randomised PREVENT-PE trial demonstrates that a personalised timing-of-birth strategy can prevent term pre-eclampsia where no effective medical prevention currently exists.

8 Dec 2025

Genome-edited immune cell therapy shows promise for treating aggressive blood cancer

A groundbreaking new treatment using genome-edited immune cells, developed by scientists at UCL (University College London) and Great Ormond Street Hospital (GOSH), has shown promising results in helping children and adults fight a rare and aggressive form of blood cancer called T-cell acute lymphoblastic leukemia (T-ALL).

8 Dec 2025

Powerful prognostic marker could enable early identification of high-risk cancer patients

Aggressive T-cell lymphoma is a rare and devastating form of blood cancer with a very low five-year survival rate.

8 Dec 2025

Combination therapy may boost survival for people with aggressive lymphoma

A new clinical trial suggests that pairing bispecific antibodies and antibody-drug conjugates with CAR T-cell therapy may sharply boost one-year progression-free survival for people with aggressive lymphoma.

8 Dec 2025

Lymphocyte levels help predict outcomes after CAR T-cell therapy in non-Hodgkin lymphoma

Measuring the lymphocytes - white blood cells that fight infection - in a patient's blood can be used to predict outcomes in non-Hodgkin lymphoma patients who receive CAR T-cell therapy, according to research from physicians at Fox Chase Cancer Center and Temple Health.

8 Dec 2025

Most T-cell/histocyte-rich large B-cell lymphoma patients can safely receive a less toxic treatment

Most patients with a rare and aggressive form of large B-cell lymphoma can safely receive a less toxic treatment than the intensive chemotherapy often used, according to new research from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.

8 Dec 2025

Why female athletes need injury prevention rules built for women, not men

This International Olympic Committee consensus synthesised evidence from over 600 studies to develop 56 injury prevention recommendations tailored to female, woman and girl athletes. It concludes that reducing injury risk requires a whole sports system approach that integrates training, policy, environment and culture, not exercise alone.

8 Dec 2025

Understanding the heterogeneity in nicotine, tobacco, and cannabis use among young Americans

Young Americans use nicotine, tobacco and cannabis in multiple ways, but smoking those items––the most dangerous method––is still involved for most users, a new University of Michigan study found.

8 Dec 2025

Timing of genetic mutation dictates childhood leukemia aggressiveness

A team of researchers at the Icahn School of Medicine at Mount Sinai has uncovered why children with the same leukemia-causing gene mutation can have dramatically different outcomes: it depends on when in development the mutation first occurs.

8 Dec 2025

Insufficient sleep may decrease life expectancy

A good night's sleep is more than a luxury: New research from Oregon Health & Science University suggests that insufficient sleep may shorten your life.

8 Dec 2025

Intellicule secures $217,941 SBIR Phase I grant to develop biomolecular modeling software

Intellicule, a software company whose solutions determine the 3D structures of biomolecules imaged with cryogenic-electron microscopy (cryo-EM), has received a $217,941 Small Business Innovation Research (SBIR) Phase I grant from the National Institutes of Health.

8 Dec 2025

Simple blood and urine tests could spare febrile infants from more invasive procedures

New evidence from a six-country study led by the Montreal Children's Hospital and Children's National Hospital shows simple blood and urine tests could spare many young infants with fevers from more invasive procedures.

8 Dec 2025

NYS Medical Cannabis Program reduces chronic pain patients' reliance on opioids

Adults with chronic pain who participated in New York State's (NYS) Medical Cannabis Program were significantly less likely to require prescription opioids, according to a new study published today in JAMA Internal Medicine and led by researchers at Albert Einstein College of Medicine and Montefiore Health System.

8 Dec 2025

Medicine News and Research

Highly sensitive CRISPR-based method designed to detect low-frequency cancer mutations

New study reveals productivity losses from substance use disorder in the U.S.

Accuracy of remote photoplethysmography drops sharply at elevated heart rates

High BMI and poor physical fitness in adolescence linked to severe bacterial infections in adulthood

Physical activity may help restore ease of movement and agility during aging

Online reference library provides a more accurate picture of drug exposure

Study reveals how brain protein KCC2 influences reward learning

A 36-week screening strategy safely reduces pre-eclampsia at term

Genome-edited immune cell therapy shows promise for treating aggressive blood cancer

Powerful prognostic marker could enable early identification of high-risk cancer patients

Combination therapy may boost survival for people with aggressive lymphoma

Lymphocyte levels help predict outcomes after CAR T-cell therapy in non-Hodgkin lymphoma

Most T-cell/histocyte-rich large B-cell lymphoma patients can safely receive a less toxic treatment

Why female athletes need injury prevention rules built for women, not men

Understanding the heterogeneity in nicotine, tobacco, and cannabis use among young Americans

Timing of genetic mutation dictates childhood leukemia aggressiveness

Insufficient sleep may decrease life expectancy

Intellicule secures $217,941 SBIR Phase I grant to develop biomolecular modeling software

Simple blood and urine tests could spare febrile infants from more invasive procedures

NYS Medical Cannabis Program reduces chronic pain patients' reliance on opioids

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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