Genetic News and Research

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Microsoft combs through millions of strains of human immunodeficiency virus (HIV)

Microsoft Research has pioneered promising new ways to combat one of humankind's most deadly viruses with advanced software typically used to analyze large computer databases and complex digital images, or to separate spam from legitimate e-mail.

23 Feb 2005

Pollution exposure during pregnancy can cause chromosomal abnormalities in fetal tissues

A new study of newborns in New York City reveals that prenatal exposure to combustion-related urban air pollutants alters the structure of chromosomes (the carriers of genes) of babies in the womb.

23 Feb 2005

Simple saliva test can predict whether children will get cavities

A simple saliva test can predict for the first time whether children will get cavities, how many cavities they will get and even which teeth are most vulnerable, USC researchers say.

23 Feb 2005

Non-invasive and invasive breast cancers share the same genetic mutations

Women diagnosed with early stage, non–invasive breast cancer who carry the same mutations in two inherited breast/ovarian cancer genes as women diagnosed with invasive breast cancer, may benefit from high risk treatment, Yale researchers report in the February 23 issue of Journal of the American Medical Association.

23 Feb 2005

Scientists have replicated hepatitis C virus (HCV) in the laboratory

For the first time, scientists have replicated hepatitis C virus (HCV) in the laboratory. The ability to replicate HCV in cell culture will allow researchers to better study the life cycle and biology of this virus and to test potential antiviral compounds, which may lead to new therapies for the liver disease that results from infection with HCV.

22 Feb 2005

Cesarean delivery is associated with an increased risk of childhood asthma hospitalization in premature infants

Cesarean delivery is associated with an increased risk of childhood asthma hospitalization in premature infants, but not in full-term infants, according to a report published in this month’s Annals of Allergy, Asthma & Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI).

22 Feb 2005

Crystallized molecular machine reveals possible new paths for treating diseases

The crystallized form of a molecular machine that can cut and paste genetic material is revealing possible new paths for treating diseases such as some forms of cancer and opportunistic infections that plague HIV patients.

21 Feb 2005

Americans support appropriate use of reproductive genetic testing

A majority of Americans believes it is appropriate to use reproductive genetic testing to avoid having a child with a life-threatening disease, or to test embryos to see if they will be a good match to provide cells to help a sick sibling, a new report of the Genetics and Public Policy Center reveals.

20 Feb 2005

Shedding new LIGHT on disease

New drugs for the 270,000 people who suffer heart attacks every year in the UK will be among the projects in Leeds' new research institute. The Leeds Institute of Genetics Health and Therapeutics (LIGHT) was opened by head of the Medical Research Council chief executive Professor Colin Blakemore yesterday.

17 Feb 2005

Studies reveal methods viruses use to sidestep immune system

A series of studies by researchers at UT Southwestern Medical Center sheds light on the mechanisms used by viruses to thwart a host's immune defenses and may aid in the development of more effective drugs to fight hepatitis C and West Nile viruses, as well as the flu and the common cold.

17 Feb 2005

Separating chromosomes improves genetic test results

A new process that helps unmask genetic mutations by separating chromosomes so they can be studied individually may improve the diagnostic yield of some genetic tests, according to findings of a Colon Cancer Family Registry study published today in the Journal of the American Medical Association.

16 Feb 2005

Programmed cell death may provide clues to cancer and autoimmune diseases therapies

Dartmouth Medical School geneticists have found links in the cell death machinery of worms and mammals, opening new avenues for studying and targeting a process vital to development and implicated in cancer and autoimmune diseases.

16 Feb 2005

Schizophrenia may arise from a single genetic defect

Researchers have long puzzled over the apparently multiple causes of complex developmental disorders such as schizophrenia. Individuals seem to be predisposed to the disease by a tragic, mysterious combination of genetics, prenatal trauma, viral infection, and early experience.

16 Feb 2005

$Link between lactose malabsorption and the occurrence of bone fracture in elderly people$

Link between lactose malabsorption and the occurrence of bone fracture in elderly people

Published in January and conducted by researchers from the Universities of Helsinki and Kuopio and the National Public Health Institute, the study investigated the relation between the genotype associated with lactose malabsorption and the occurrence of bone fracture in the elderly. The study included 483 elderly people in the City of Vantaa – 377 women and 106 men – all over 85 years of age.

16 Feb 2005

Genetic manipulation cuts nerve damage, boosts life span

A novel genetic manipulation significantly extends the life spans of flies by reducing the amount of wear and tear suffered by nerve cells in adults, according to new work published in Cell Metabolism. The findings support the idea that therapies designed to protect the adult nervous system by curbing the production of damaging free radicals might effectively increase longevity in other animals, including humans, the researchers said.

15 Feb 2005

Novel genetic test helps detect mutations that may be missed by conventional DNA test

Researchers have identified a genetic test that when used with DNA testing would detect a higher number of genetic mutations in colorectal cancer patients, according to a study in the February 16 issue of JAMA, a theme issue on medical applications of biotechnology.

15 Feb 2005

New technique to identify fetal genetic material from amniotic fluid

A preliminary report suggests that cell-free fetal messenger RNA (ribonucleic acid) can be extracted from amniotic fluid (fluid around the fetus), and then be analyzed to study gene expression changes that may reflect the well-being of the fetus, according to a paper in the February 16 issue of JAMA, a theme issue on medical applications of biotechnology.

15 Feb 2005

New simple and cost-effective method of diagnosing hereditary genetic disorders

A technique called size-fractionation performed on a sample of the mother's blood allows researchers to identify fetal DNA molecules separate from maternal DNA as a way to determine which pregnancies may be at risk for genetic disorders, according to a preliminary communication in the February 16 issue of JAMA, a theme issue on medical applications of biotechnology.

15 Feb 2005

Angiogenesis inhibitor molecules defend against the development and spread of cancer

Research led by investigators at Beth Israel Deaconess Medical Center (BIDMC) helps explain how a group of angiogenesis inhibitor molecules serve as an important defense mechanism against the development and spread of cancer, offering key insights into why cancerous tumors grow at different rates among different individuals.

15 Feb 2005

Exposure of expectant mothers to urban air pollution may alter the structure of babies' chromosomes while in the womb

A new study of 60 newborns in New York City reveals that exposure of expectant mothers to combustion-related urban air pollution may alter the structure of babies' chromosomes while in the womb.

15 Feb 2005

Genetic News and Research

Microsoft combs through millions of strains of human immunodeficiency virus (HIV)

Pollution exposure during pregnancy can cause chromosomal abnormalities in fetal tissues

Simple saliva test can predict whether children will get cavities

Non-invasive and invasive breast cancers share the same genetic mutations

Scientists have replicated hepatitis C virus (HCV) in the laboratory

Cesarean delivery is associated with an increased risk of childhood asthma hospitalization in premature infants

Crystallized molecular machine reveals possible new paths for treating diseases

Americans support appropriate use of reproductive genetic testing

Shedding new LIGHT on disease

Studies reveal methods viruses use to sidestep immune system

Separating chromosomes improves genetic test results

Programmed cell death may provide clues to cancer and autoimmune diseases therapies

Schizophrenia may arise from a single genetic defect

Link between lactose malabsorption and the occurrence of bone fracture in elderly people

Genetic manipulation cuts nerve damage, boosts life span

Novel genetic test helps detect mutations that may be missed by conventional DNA test

New technique to identify fetal genetic material from amniotic fluid

New simple and cost-effective method of diagnosing hereditary genetic disorders

Angiogenesis inhibitor molecules defend against the development and spread of cancer

Exposure of expectant mothers to urban air pollution may alter the structure of babies' chromosomes while in the womb

Sequencing & Genomics: Elevating Science and Healthcare eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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