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Metformin reduces long COVID risk according to ACTIV-6 clinical trial

New findings from the ACTIV-6 randomized clinical trial provide important confirmation of prior clinical trial results that metformin, a widely available and inexpensive medication with an established safety record, reduced the risk of clinician-diagnosed long COVID when started during acute COVID-19 infection.

11 Jun 2026

Texas Children’s Hospital and Baylor researcher joins ARIA IMPACT Network to advance autism therapies

Dr. Jimmy Holder, associate professor in pediatrics at Baylor College of Medicine and Principal investigator at the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, and his team have received a grant for up to $17.25 million from Aligning Research to Impact Autism (ARIA) to become a part of the Innovative Medicine and Precision Approaches to Clinical Trials (IMPACT) Network.

11 Jun 2026

Remote monitoring does not beat usual care for sepsis patients

Remote monitoring isn't a panacea for reducing readmissions across all conditions - and for some patients, clinicians should proceed with caution, clinical trial results published today in JAMA Network Open suggest.

11 Jun 2026

Blood pressure control may be the key to optimizing stroke treatment after thrombectomy

Blood pressure management after thrombectomy for acute ischemic stroke may require a change in approach.

11 Jun 2026

Tranexamic acid reduces surgical transfusions without raising clot risks

A landmark clinical trial published in the prestigious New England Journal of Medicine found that tranexamic acid reduced transfusions across major surgeries without increasing the risk of dangerous blood clots.

10 Jun 2026

Public health messaging still beats AI chatbots for HPV vaccine promotion

The study finds that AI chatbots boost HPV vaccination intent temporarily, but public health resources are crucial for lasting impact on vaccination decisions.

10 Jun 2026

Injectable semaglutide may improve fertility outcomes in PMOS

Researchers at the University of Colorado Anschutz have published a proof-of-concept study in Fertility and Sterility demonstrating that injectable semaglutide may offer meaningful reproductive benefits for women with polyendocrine metabolic ovarian syndrome (PMOS), formerly known as polycystic ovary syndrome (PCOS).

9 Jun 2026

Apitegromab helps tirzepatide users lose fat while preserving lean mass

A phase 2 trial found that apitegromab plus tirzepatide reduced lean body mass loss by 1.9 kg compared with tirzepatide plus placebo after 24 weeks, while overall weight loss remained similar.

9 Jun 2026

Obesity drug mazdutide reduces weight and waist size in major trial

Once-weekly 9 mg mazdutide produced clinically meaningful weight loss in Chinese adults with obesity, reducing body weight by 16.65% after 60 weeks versus 1.50% with placebo. The phase 3 GLORY-2 trial also found improvements in waist circumference, systolic blood pressure, and lipid markers, but gastrointestinal adverse events were common.

9 Jun 2026

AI-powered chatbots no better than written public health materials for vaccine promotion

A new Penn-led randomized controlled trial has found that AI-powered chatbots can make vaccine-hesitant parents more likely to say they will immunize their children against human papillomavirus (HPV), but no more than standard written public health materials.

9 Jun 2026

New digital platform treats insomnia and anxiety in seniors

Cognitive behavioral therapies for insomnia (CBT-I) are increasingly being delivered online in order to improve accessibility.

9 Jun 2026

New game-based therapy retrains muscles after a stroke

A customized throw-back video game may offer a surprisingly futuristic path to stroke recovery.

9 Jun 2026

Experimental two‑in‑one vaccine shows success in human LASSARAB trial

Researchers from Thomas Jefferson University and the University of Maryland School of Medicine have reported encouraging results from the first human clinical trial of LASSARAB, an experimental vaccine designed to protect against Lassa fever and rabies in a single formulation.

9 Jun 2026

Common joint supplement may accelerate Alzheimer's disease progression

New research has found an association between taking glucosamine, a popular over-the-counter supplement used for joint pain, and a higher likelihood of progressing from mild cognitive impairment to Alzheimer's disease.

9 Jun 2026

Oral GLP-1 RA reduces blood glucose and bodyweight among people with type 2 diabetes

Oral GLP-1 medications have the potential to increase access to therapies that can help lower blood sugar and reduce bodyweight.

8 Jun 2026

Online tool transforms patient experience in national cancer trials

In a step forward for patient-centered cancer research, a new pilot project reveals that 84% of participants had a positive experience using a newly developed online tool created by the Alliance for Clinical Trials in Oncology called the Participant Engagement Portal (PEP).

8 Jun 2026

New project launches to advance chikungunya vaccine in Africa

Funded by the Global Health EDCTP3 Joint Undertaking, a new €15.3 million project coordinated by Institut Pasteur brings together seven partners across four continents to advance clinical trials and prepare for the manufacturing of a chikungunya vaccine in Africa.

8 Jun 2026