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Study explores differentially expressed immune genes for COVID-19 patient stratification

In a new study, researchers determined the transcriptional signatures associated with the severity of COVID-19.

7 Mar 2022

Potential molecular and clinical biomarkers of COVID-19 severity

Researchers have reviewed the currently published data examining the potential molecular and clinical biomarkers of COVID-19 severity.

4 Mar 2022

Study does not find association between hematological parameters and COVID-19-related hospitalization

Researchers examine the genetic factors influencing hematological parameters in SARS-CoV-2 infection.

4 Mar 2022

Assessing the potential of IFNa subtypes in suppressing SARS-CoV-2

A recent study analyzes IFNa subtypes for their therapeutic potential against SARS-CoV-2 and identified the underlying immune signatures and mechanisms.

3 Mar 2022

Study explores signature gut microbiome connection with immune checkpoint inhibitor response in advanced melanomas

Researchers from different countries performed a meta-analysis of real-world cross-cohorts and provided an association of the gut microbiome with immune checkpoint inhibitors response in patients with advanced melanomas.

2 Mar 2022

MAIT cells exercise complex functions and may be targets for future immunotherapies and vaccines

A Stony Brook University physician-scientist has identified that mucosal-associated invariant T (MAIT) cells, an unconventional form of immune cell, exercise several complex roles during healthy and disease states.

24 Feb 2022

White blood cell count as a prognostic indicator of COVID-19

Based on a new study, researchers concluded WBC count variations worsen clinical outcomes such as severity, mortality, and hospital discharge rates leading to a poorer prognosis in COVID-19 patients.

23 Feb 2022

Study suggests anti-SARS-CoV-2 antibodies may persist lifelong post-infection

Researchers attempted to delineate the duration and stability of anti-SARS-CoV-2 antibodies in patients who had recovered from the COVID-19 infection.

22 Feb 2022

T-cell responses linked with protection from SARS-CoV-2 infection in vaccinated individuals with or without cancer

T-cell responses directed against the receptor-binding domain of the SARS-CoV-2 spike protein were associated with protection from SARS-CoV-2 infection in vaccinated individuals with or without cancer, with lower T-cell responses observed in patients with blood cancers.

18 Feb 2022

New finding may aid in development of vaccines against future animal-to-human viral diseases

A future vaccine providing protection against a wide range of coronaviruses that jump from their original animal hosts to humans - including SARS-CoV-2, the cause of COVID-19 - may be possible, say Johns Hopkins Medicine researchers, based on findings from their recent study.

17 Feb 2022

Study explores differential immune responses against SARS-CoV-2 in adults and children

A new study revealed that the immune responses against SARS-CoV-2 and the clinical course of COVID-19 differs between children and adults.

17 Feb 2022

Assessing potential allergic reactions in COVID-19 vaccinated patients

Researchers analyze suspected reactions in patients vaccinated with the first and/or second dose of SARS-CoV-2 vaccines.

13 Feb 2022

Novel fast-spreading HIV-1 variant found circulating in the Netherlands

Researchers identify 17 individuals who were infected with a highly virulent variant of HIV-1.

7 Feb 2022

Cerebrovascular impairment persists months after severe acute COVID-19, UK study

Researchers in the United Kingdom have conducted an observational cohort study on hospitalized patients and have found that the degree of severity of acute coronavirus disease 2019 (COVID-19) predicts the occurrence of chronic cerebrovascular impairment. The study further suggests that the levels of cerebrovascular impairment are associated with worse cognitive, mental, and physical well-being.

7 Feb 2022

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Researchers from China summarized the representative structures of SARS-CoV-2 proteins and discussed the development of novel therapeutic agents for targeting these proteins to treat and prevent COVID-19.

2 Feb 2022

Research shows minks mimic severe COVID-19 symptoms, including ARDS

Minks may be a suitable animal model for testing severe COVID-19 infections, finds a recent bioRxiv* preprint study. While mice and ferrets are used in preclinical severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is currently no model specific to severe disease.

30 Jan 2022

Lymphocyte News and Research

Study explores differentially expressed immune genes for COVID-19 patient stratification

Potential molecular and clinical biomarkers of COVID-19 severity

Study does not find association between hematological parameters and COVID-19-related hospitalization

Assessing the potential of IFNa subtypes in suppressing SARS-CoV-2

Study explores signature gut microbiome connection with immune checkpoint inhibitor response in advanced melanomas

MAIT cells exercise complex functions and may be targets for future immunotherapies and vaccines

White blood cell count as a prognostic indicator of COVID-19

Study suggests anti-SARS-CoV-2 antibodies may persist lifelong post-infection

T-cell responses linked with protection from SARS-CoV-2 infection in vaccinated individuals with or without cancer

New finding may aid in development of vaccines against future animal-to-human viral diseases

Study explores differential immune responses against SARS-CoV-2 in adults and children

Assessing potential allergic reactions in COVID-19 vaccinated patients

Novel fast-spreading HIV-1 variant found circulating in the Netherlands

Cerebrovascular impairment persists months after severe acute COVID-19, UK study

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Research shows minks mimic severe COVID-19 symptoms, including ARDS

A synthesis of evidence sheds light on major immune components and mechanisms involved in COVID-19

Early-stage alveolar epithelial cell necrosis linked to COVID-19-induced acute respiratory distress syndrome

Study shows enduring T-cell immunity up to at least 1-year after SARS-CoV-2 infection

Exploring hematological alterations in COVID-19 patients

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