Neutrophils News and Research

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Neutrophils may play a key role in COVID-19-related thrombosis

A team of researchers in Italy have published a study suggesting that rather than platelets, neutrophils could be playing the lead role in thrombotic complications associated with COVID-19.

9 Dec 2020

FASLG gene may drive cytokine-linked adverse COVID-19 outcomes with age

A new study published on the preprint server bioRxiv in December 2020 reveals the role played by certain genetic factors in this group, in particular the FASLG gene belonging to the tumor necrosis factor (TNF) family.

8 Dec 2020

Higher degrees of necrosis are inked to poor survival in brain cancer patients

White blood cells are part of many immune system responses in the human body. New research shows that a specific type of those cells may cause brain cancer tissues to die – but that's not good news, according to researchers at Penn State College of Medicine and Penn State Cancer Institute.

8 Dec 2020

Mysterious particle found in the blood of people with sepsis

Researchers at La Jolla Institute for Immunology have found that people with sepsis have never-before-seen particles in their blood.

5 Dec 2020

Study provides mechanistic insights about the role of neutrophils in psoriasis pathogenesis

Psoriasis has always been a common disease. Historically, its causes were obscure and surrounded by stigma; it wasn't until recently that scientists categorized it as an autoimmune condition.

4 Dec 2020

New reviews provide timely updates for scholars, professionals focused on antimicrobial research

The initial chapter of 'Anti-infective Research and Development: Updates on Infection Mechanisms and Treatments' covers the mode of action of natural antimycobacterial compounds such as nordihydroguaiaretic acid, α-mangostin and allicin, as well as antimicrobial peptides and their role in the innate and adaptive immune response leading to the decrease of microbial resistance.

1 Dec 2020

Healthy diet plays vital role in warding off COVID-19

A researcher at the School of Human Development and Health, Faculty of Medicine, University of Southampton, explored nutrition's role in boosting the immune system to combat COVID-19 infection.

29 Nov 2020

Female reproductive hormones may be protective against COVID-19

In an article recently published in Trends in Endocrinology & Metabolism, Graziano Pinna from the University of Illinois in Chicago outlines some of the evidence suggesting that female reproductive hormones may play a role in the sex bias that has been observed in coronavirus disease 2019 (COVID-19).

29 Nov 2020

Transgenic mouse model could recapitulate severe COVID-19 in humans

Researchers in the United States and Canada have described the potential for a transgenic mouse model to serve as an effective platform for the study of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and severe disease course in humans.

26 Nov 2020

Researchers discover blood gene signatures that can predict COVID-19 severity

A team of scientists from the University of Chicago, NCH Healthcare System and the University of South Florida has identified a specific set of genes associated with a poor prognosis of COVID-19.

26 Nov 2020

How COVID-19 compares to other respiratory illnesses

A team of scientists from Israel and the United States has compared the disease presentation and progression between in-hospital patients with coronavirus disease 2019 (COVID-19) and other respiratory illnesses such as influenza.

23 Nov 2020

COVID-19 during pregnancy can cause placental inflammation and impaired immunity

A new study conducted by a team of researchers at Johns Hopkins University, USA, has observed how pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) show stunted antiviral immune responses.

18 Nov 2020

Severe COVID-19 complications linked to gut barrier breakdown

A new study claims that severe COVID-19 is caused by a positive feedback loop triggered by systemic inflammation and mediated by abnormal gut permeability. This finding could potentially help open up new avenues of treatment.

18 Nov 2020

SARS-CoV-2 causes a unique cytokine storm, study finds

A new study published on the preprint server medRxiv* in November 2020 reports some of the unique elements of COVID-19-induced CRS and how understanding these distinctive characteristics of the disease could help in formulating specific interventions and therapies.

18 Nov 2020

Hydrogen therapy may help severely ill COVID-19 patients

Researchers from the Department of Critical Care Medicine, Sichuan Provincial People's Hospital, Chengdu in China, have explored the possibility of using hydrogen therapy on severely ill COVID-19 patients. The team published their study's findings, titled "Hydrogen: A Potential New Adjuvant Therapy for COVID-19 Patients," in the latest issue of the journal Frontiers in Pharmacology.

17 Nov 2020

Study looks at SARS-CoV-2 RNA contamination in COVID-19 isolation ward of a hospital

To try and shed more light on SARS-CoV-2’s transmission, a research group based in Italy examined a COVID-19 isolation ward in a Milan hospital to evaluate the level of contamination present in the air and on surfaces with SARS-CoV-2 RNA (the virus’s genetic material).

15 Nov 2020

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

Scientists in Taiwan recently published a report on their use of anti-neutrophil strategies to treat acute respiratory distress syndrome (ARDS) – a life-threatening condition that can arise in critical COVID-19 cases – in the journal Frontiers in Pediatrics.

15 Nov 2020

COVID-19-associated pulmonary aspergillosis caused by aspergillus fumigatus

A new study published on the preprint server bioRxiv in November 2020 discusses the characteristics of COVID-19 associated pulmonary aspergillosis (CAPA).

10 Nov 2020

White blood cells can be used to attack tumors after completing a special training

Scientists at the National Center for Tumor Diseases Dresden and Dresden University Medicine, together with an international team of researchers, were able to demonstrate that certain white blood cells, so-called neutrophil granulocytes, can potentially - after completing a special training program - be utilized for the treatment of tumors.

6 Nov 2020