Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Chemical signatures in blood could help detect gallbladder cancer

Researchers at Tezpur University in Assam, India, working with scientists at the University of Illinois Urbana-Champaign, have identified distinct chemical signatures in blood that could help detect gallbladder cancer earlier.

25 Feb 2026

Small RNA molecules can accurately predict survival in older adults

As people age, it becomes harder to know who is on track for healthy years ahead and who may be at higher risk for serious decline.

25 Feb 2026

New 3D liver reconstructions show how cirrhosis reshapes organ architecture

Never-before-seen 3D reconstructions of human liver tissue have been created at a cellular level. The details obtained by a team of UW Medicine and University of Washington engineers and physicians capture the spatial microstructure of multiple lobes of this multitasking organ.

23 Feb 2026

Study identifies PPP2R5C blood marker that may detect Alzheimer’s disease earlier

Emerging evidence suggests reduced plasma PPP2R5C levels may serve as an early indicator of Alzheimer’s disease before overt clinical symptoms appear. The protein appears linked to tau regulation, autophagy pathways, and cognitive decline, supporting its potential diagnostic relevance.

22 Feb 2026

Blood test models predict when Alzheimer’s symptoms may start years in advance

Researchers developed plasma p-tau217–based clock models that estimate when cognitively unimpaired individuals with Alzheimer’s pathology may develop symptomatic disease. The models predicted symptom onset within about three to four years and may help improve clinical trial selection while remaining unsuitable for individual clinical decisions at present.

22 Feb 2026

Single prenatal exposure to fungicide linked to disease across 20 generations

A single exposure to a toxic fungicide during pregnancy can increase the risk of disease for 20 subsequent generations - with inherited health problems worsening many generations after exposure.

20 Feb 2026

Discovery offers hope for reducing immune-related heart risks in cancer patients

For many people diagnosed with cancer, treatment with immune checkpoint inhibitors (ICIs) has dramatically extended lives.

20 Feb 2026

Grant supports research into how microglia may spread toxic tau in Alzheimer’s

A researcher with the Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases at UT Health San Antonio has received a two-year, $402,500 grant award from the Cure Alzheimer's Fund to study how microglia, the brain's resident immune cells, paradoxically might contribute to the spread of toxic forms of tau protein in the disease.

20 Feb 2026

Distinct gut toxicity patterns emerge with targeted cancer treatments

A new paper was published in Volume 13 of Oncoscience on February 6, 2026, titled "Gastrointestinal toxicity of targeted cancer therapies in the United States: Clinicopathologic patterns, FDA safety frameworks, and implications for national patient protection."

20 Feb 2026

Major grant supports investigation into infectious triggers of Alzheimer’s and Parkinson’s

The Hebrew University of Jerusalem is proud to announce the establishment of the Sally Einstein Brain Research Program, made possible by a ₪1,000,000 (USD $300,930) grant from the Sim Einstein Research Foundation, Inc.

19 Feb 2026

Single blood test predicts onset of Alzheimer’s symptoms years ahead

Researchers at Washington University School of Medicine in St. Louis have developed a method to predict when someone is likely to develop symptoms of Alzheimer's disease using a single blood test.

19 Feb 2026

IFN-γ identified as a powerful blood biomarker for Alzheimer’s

This study identifies IFN-γ as a crucial blood-based biomarker for Alzheimer's, revealing its role in microglial inflammation and genetic risk interactions.

19 Feb 2026

Protein made by stressed cancer cells helps tumors to evade immune attack

A protein made by stressed cancer cells helps lung and pancreatic tumors evade the immune system, a new study shows.

18 Feb 2026

Developmental ANGPTL4 deficiency protects mice from colitis and tumors

A novel study using a mouse model has found that the absence of the angiopoietin-like 4 (ANGPTL4) protein during development triggers a long-lasting reprogramming of the immune system that protects against intestinal inflammation.

18 Feb 2026

Scientists uncover nanoplastics in brain tissue and question their role in neurological disease

Emerging evidence suggests nanoplastics accumulate in human tissues including the brain and may contribute to neuroinflammation and neurodegenerative disease pathways. However, causality, exposure routes, and long-term health effects remain uncertain and require coordinated research.

17 Feb 2026

AI tool can accurately predict colorectal cancer risk in UC-LGD patients

People with ulcerative colitis (UC), a chronic inflammatory bowel disease, are up to four times more likely to develop colorectal cancer than the general population.

17 Feb 2026

NCCN publishes new guidelines for management of pediatric soft tissue sarcomas

The National Comprehensive Cancer Network (NCCN) today published new NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Pediatric Soft Tissue Sarcomas.

17 Feb 2026

Dysplasia grade predicts colorectal cancer risk in people with IBD

People with inflammatory bowel disease (IBD) and precancerous colorectal lesions are much more likely to develop colorectal cancer, a new study shows.

16 Feb 2026

Synergistic drug pair shows promise for spinal cord injury recovery

Spinal cord injury remains one of the most challenging neurological conditions to treat, largely because damage continues to worsen long after the initial trauma.

16 Feb 2026

Advanced use of MRI aids in accurate identification of rare, atypical parkinsonian disorders

An international study led by researchers from the Sant Pau Research Institute (IR Sant Pau) shows that advanced use of magnetic resonance imaging (MRI) allows much more accurate identification of patients with progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD).

16 Feb 2026