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TAAR1 mutation impairs brain signaling in schizophrenia

A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely silence a brain receptor that pharmaceutical companies are racing to target with new drugs.

6 Jan 2026

Why individual differences hold the key to unlocking psychiatric mysteries

In a revealing Genomic Press Interview published today in Genomic Psychiatry, Dr. Noritaka Ichinohe challenges a foundational assumption that has quietly constrained psychiatric research for decades: the belief that meaningful explanation requires averaging away individual differences.

6 Jan 2026

Two isoforms of a cellular energy sensor play distinct, opposing roles in Alzheimer's disease

A comprehensive mini-review published today after peer review in Brain Medicine by Dr. Tao Ma and colleagues at Wake Forest University School of Medicine synthesizes emerging evidence that two isoforms of a critical cellular energy sensor play distinct, and sometimes opposing, roles in Alzheimer's disease.

6 Jan 2026

Understanding sevoflurane-induced neurogenesis inhibition and cognitive dysfunction in children

Every year, millions of infants and children undergo surgery under general anesthesia in the world. Sevoflurane is a commonly used pediatric anesthetic. Its exposure during brain development has been shown to inhibit neurogenesis and cause cognitive dysfunction in animal models.

5 Jan 2026

Researchers identify hundreds of genes essential for the development of brain cells

An international research team identified hundreds of genes essential for the development of brain cells, including one gene linked to a severe neurodevelopmental disorder not previously described.

5 Jan 2026

Weaker and fragmented circadian rhythms linked to higher dementia risk

Circadian rhythms that are weaker and more fragmented are linked to an increased risk of dementia, according to a new study published on December 29, 2025, in Neurology®, the medical journal of the American Academy of Neurology.

4 Jan 2026

Advertisements promising patients a ‘dream body’ with minimal risk get little scrutiny

Lenia Watson-Burton, a 37-year-old U.S. Navy administrator, expected that cosmetic surgery would get rid of stubborn fat quickly and easily — just as the web advertising promised.

1 Jan 2026

Artificial intelligence unlocks new frontiers in RNA drug design

In the realm of modern medicine, RNA-based therapies have emerged as a promising avenue, with significant advancements in metabolic diseases, oncology, and preventive vaccines. A recent article published in Engineering titled "The Future of AI-Driven RNA Drug Development" by Yilin Yan, Tianyu Wu, Honglin Li, Yang Tang, and Feng Qian, explores how artificial intelligence (AI) can revolutionize RNA drug development, addressing current limitations and offering new opportunities for innovation.

31 Dec 2025

Plasmid-borne resistance drives global expansion of dangerous Klebsiella strains

A recent study published in Engineering has shed light on the transmission and epidemiological trends of tmexCD1-toprJ1-positive Klebsiella pneumoniae across various ecological niches, highlighting the potential threat this antibiotic-resistant bacterium poses to global public health.

31 Dec 2025

Novel method can generate functional organoids from human adult adipose tissue

A recent study published in Engineering has unveiled a novel approach to generating functional organoids from human adult adipose tissue.

30 Dec 2025

Study sheds new light on the role of NSUN2 protein in cardiac hypertrophy and heart failure

A recent study published in Engineering has shed new light on the role of the protein NSUN2 in the development of cardiac hypertrophy and heart failure.

30 Dec 2025

Dihydrotanshinone I induces autophagic cell death in ovarian cancer

A recent study published in Engineering has shed light on the potential therapeutic effects of dihydrotanshinone I (DHT), a compound derived from the traditional Chinese herb Salvia miltiorrhiza, on ovarian cancer.

30 Dec 2025

Periodontal bacterial load associated with disease severity in multiple sclerosis

Increasing evidence suggests that the severe gum disease, periodontitis, may contribute to central nervous system disorders through chronic inflammation.

30 Dec 2025

New roadmap guides antiseizure medication adjustments during pregnancy and postpartum

For the first time, clinicians have access to a clear, evidence-based roadmap for adjusting antiseizure medication doses during pregnancy and after childbirth.

30 Dec 2025

Conversation may quietly impair the visual foundations of driving

New research from Fujita Health University reveals that talking can subtly delay the eyes’ ability to detect and stabilize on visual information.

26 Dec 2025

Older age affects functional recovery after spinal cord injury

A new study published on December 23, 2025, in Neurology, the medical journal of the American Academy of Neurology, looks at how age may affect recovery for people with spinal cord injuries.

23 Dec 2025

Prebiotic microcapsules deliver pterostilbene to the colon to alleviate ulcerative colitis

A team led by clinicians and engineers has wrapped the plant-derived polyphenol pterostilbene (PSB) into prebiotic alginate/resistant-starch microcapsules coated with chitosan and shown that oral administration dampens dextran-sulfate-sodium (DSS) colitis in mice.

23 Dec 2025

Reframing the role of MCL1 in cancer signaling and metabolism

A study by the Mildred Scheel Early Career Center group led by Dr. Mohamed Elgendy at the TUD Faculty of Medicine provides fundamental insights into cancer biology.

22 Dec 2025

Splicing regulator U2AF1 promotes angiogenesis in cardiac injury

A study published in Engineering shows that a protein called U2 small nuclear RNA auxiliary factor 1 (U2AF1), released by immune cells known as macrophages, helps grow new blood vessels in the heart after a myocardial infarction (MI) by altering how the gene Yap1 is spliced.

22 Dec 2025

Guns marketed for personal safety fuel public health crisis in Black communities

Leon Harris, 35, is intimately familiar with the devastation guns can inflict. Robbers shot him in the back nearly two decades ago, leaving him paralyzed from the chest down. The bullet remains lodged in his spine.

19 Dec 2025

Website News and Research

TAAR1 mutation impairs brain signaling in schizophrenia

Why individual differences hold the key to unlocking psychiatric mysteries

Two isoforms of a cellular energy sensor play distinct, opposing roles in Alzheimer's disease

Understanding sevoflurane-induced neurogenesis inhibition and cognitive dysfunction in children

Researchers identify hundreds of genes essential for the development of brain cells

Weaker and fragmented circadian rhythms linked to higher dementia risk

Advertisements promising patients a ‘dream body’ with minimal risk get little scrutiny

Artificial intelligence unlocks new frontiers in RNA drug design

Plasmid-borne resistance drives global expansion of dangerous Klebsiella strains

Novel method can generate functional organoids from human adult adipose tissue

Study sheds new light on the role of NSUN2 protein in cardiac hypertrophy and heart failure

Dihydrotanshinone I induces autophagic cell death in ovarian cancer

Periodontal bacterial load associated with disease severity in multiple sclerosis

New roadmap guides antiseizure medication adjustments during pregnancy and postpartum

Conversation may quietly impair the visual foundations of driving

Older age affects functional recovery after spinal cord injury

Prebiotic microcapsules deliver pterostilbene to the colon to alleviate ulcerative colitis

Reframing the role of MCL1 in cancer signaling and metabolism

Splicing regulator U2AF1 promotes angiogenesis in cardiac injury

Guns marketed for personal safety fuel public health crisis in Black communities

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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