immunity News and Research

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DNA origami vaccine platform shows promise against multiple infectious viruses

The COVID-19 pandemic brought messenger RNA (mRNA) vaccines to the forefront of global health care. After their clinical trial stages, the first COVID-19 mRNA vaccine was administered on 8 December 2020 and mathematical models suggest that mRNA vaccines prevented at least 14.4 million deaths from COVID-19 in the first year alone.

11 Mar 2026

Global study reveals how inequality limits access to exercise and why it matters for health

A global analysis of physical activity data from 68 countries shows large socioeconomic and gender inequalities in access to choice-based exercise, particularly active leisure. The study also synthesizes evidence linking physical activity to lower risks of severe infectious disease, depression, and cancer mortality, and proposes a new “physical activity for health and wellbeing” public health framework.

10 Mar 2026

Sleep and diet emerge as key drivers of immunome variation

Immunome (immune cells and functions) variations are closely related to human health. Various exposures, including the external environment and personal lifestyles, are important factors affecting the immune system.

9 Mar 2026

Researchers validate Mpox antibody test during outbreak in Rwanda

An antibody test for the infectious disease Mpox was successfully developed during the new clade 1b outbreak in Rwanda, the first time that an assay of its kind has been validated within this setting.

9 Mar 2026

Microbial ecosystems influence success of cancer checkpoint immunotherapy

Immune checkpoint inhibitors targeting PD-1 and PD-L1 have revolutionized cancer therapy, delivering long-term survival benefits in several malignancies.

9 Mar 2026

Scientists identify ANKIB1 as key regulator of innate immune signaling

Innate immune sensors – known as pattern recognition receptors (PRRs) – detect specific molecular components of bacterial or viral intruders.

6 Mar 2026

This doctor-senator who backed RFK Jr. now faces a fight for his job — and his legacy

The ambitious liver doctor would go just about anywhere in his home state to give people the hepatitis B vaccine.

6 Mar 2026

A novel approach to improving survival in treatment-resistant cancers

Researchers at the National University of Singapore (NUS) have identified a protein called tyrosine phosphatase 1B (PTP1B) as a potential "switch" that can modulate a type of cancer cell death known as immunogenic cell death (ICD).

6 Mar 2026

No evidence probiotic skincare can improve mood

Current findings reveal no support for emotional benefits from probiotic cosmetics, highlighting the need for further investigation into neurocosmetics.

5 Mar 2026

AI pinpoints why vaccine responses vary globally

How people with compromised immune systems respond to vaccines is an important area of immunological research. A new study led by York University found that not only could machine-learning models accurately pinpoint differences in healthy controls and those living with HIV, but also found outliers in both groups that provide fascinating glimpses into the complex nature of the immune system and what personalized medicine could look like in the future, accounting for variables such as age, comorbidities and genetics.

4 Mar 2026

Why measles remains one of the most contagious viral diseases worldwide

This review synthesizes current evidence on measles virus biology, immune responses, complications, treatments, and prevention strategies. It highlights how measles can suppress immune memory, increasing susceptibility to other infections, and underscores vaccination as the most effective control measure.

4 Mar 2026

Dietary fat ratios impact the strength of immune cells and ability to fight disease

The types of fats we consume directly impacts the survival and strength of the body's immune cells and ability to fight disease, researchers have found.

4 Mar 2026

Researchers identify TRIM13 protein as key driver of immune suppression in sepsis

Dendritic cells (DCs) are increasingly recognized as important contributors to sepsis-associated immune dysfunction.

4 Mar 2026

Early interventions provide academic benefits for children with developmental delays or disabilities

Children who received Early Intervention (EI) services before age 3 were more likely to meet third-grade academic standards in math and English language arts (ELA), according to a new study by researchers at Columbia University Mailman School of Public Health and the New York City Health Department. The findings are published in JAMA Network Open.

2 Mar 2026

Study reveals cellular and metabolic landscape of lymph node metastasis in breast cancer

A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that drive the spread of breast cancer.

2 Mar 2026

NLRP3 inflammasome plays dual, time-dependent roles during acute wound healing

Wound healing is a multistep biological process involving inflammation, tissue formation, and remodeling.

2 Mar 2026

MERLIN algorithm unlocks immune cell location memory in organs

A new AI-based method reconstructs spatial information about where immune cells were originally located in an organ, even after these cells have been removed from the tissue and analyzed individually.

2 Mar 2026

How zinc deficiency could worsen heart inflammation and what that means for patients

This review examines how zinc regulates inflammatory and redox signaling pathways involved in myocarditis and pericarditis, highlighting mechanisms such as NF-κB inhibition and the redox zinc switch. The authors conclude that maintaining optimal zinc status may support cardiovascular resilience, while emphasizing that clinical translation requires further targeted trials.

1 Mar 2026

Study maps how NF-κB regulates gene expression in cells

To further the quantitative understanding of cellular decision making, Dr. Gregory Reeves and his team in the chemical engineering department have worked to interpret how a transcription factor dictates the alteration of gene expression in cells.

27 Feb 2026