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Duke engineers develop AI platform to target undruggable disease proteins

Biomedical engineers at Duke University have developed an AI-based platform that designs short proteins, termed peptides, capable of binding and destroying previously undruggable disease-causing proteins.

31 Jan 2025

Trump’s order on gender-affirming care escalates reversal of trans rights

President Donald Trump ratcheted up his administration's reversal of transgender rights on Tuesday with an executive order that seeks to intervene in parents' medical decisions by prohibiting government-funded insurance coverage of puberty blockers or surgery for people under 19.

31 Jan 2025

Breakthrough model simulates human bone marrow function in the lab

Hidden within our bones, marrow sustains life by producing billions of blood cells daily, from oxygen-carrying red cells to immune-boosting white cells.

31 Jan 2025

Antibody therapy provides protection against severe H5N1 avian flu in monkeys

A prophylactic antibody-based immune therapy protects monkeys against severe disease caused by H5N1 avian flu, University of Pittsburgh and NIH Vaccine Research Center researchers report today in Science.

30 Jan 2025

Psilocybin promotes lasting belief change by altering neural entropy

Psilocybin significantly reduces confidence in negative self-beliefs four weeks after administration, with effects linked to unitive experiences and neural entropy, suggesting a potential pathway for long-term cognitive restructuring.

30 Jan 2025

New AI approach enhances personalized medicine in cancer care

Personalized medicine aims to tailor treatments to individual patients. Until now, this has been done using a small number of parameters to predict the course of a disease.

30 Jan 2025

Revolutionizing diabetes care with innovative targets and therapeutic options

A thorough examination of modern drugs that target particular receptors and metabolic pathways for glucose and fat metabolism is presented. Recent research has revealed innovative targets and therapeutic options.

30 Jan 2025

PROTAC technology offers hope for treating castration-resistant prostate cancer

Announcing a new publication for Acta Materia Medica journal. Prostate cancer (PrCa) is the most prevalent urogenital cancer affecting men.

30 Jan 2025

ALPK2 identified as promising new therapeutic target for treatment of heart failure

Tatsuya Yoshida, Mikito Takefuji, and Toyoaki Murohara in the Department of Cardiology, Nagoya University Graduate School of Medicine, identified an enzyme, alpha-kinase 2 (ALPK2) that is specifically expressed in the heart.

30 Jan 2025

Higher intensity walking program boosts mobility in stroke survivors

A progressively higher-intensity walking exercise program combined with standard physical therapy significantly improved the quality of life and mobility in stroke survivors, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2025.

30 Jan 2025

Cancer-fighting virus T-VEC helps shrink tough-to-treat skin tumors

Talimogene laherparepvec (T-VEC) demonstrates efficacy in cutaneous BCC, enhancing resectability and altering immune cell composition with low adverse events.

30 Jan 2025

Telehealth companies boost ad spending while taking on more complex medicine

Shannon Sharpe was having one of those 15-minutes-of-internet-infamy moments. Social media blew up in September after the retired Denver Broncos tight end — accidentally, he later said — broadcast some of his intimate activities online.

30 Jan 2025

New research shines light on position-specific hallmarks of cancer

A team led by the Cancer Immunogenomics group at the Josep Carreras Leukaemia Research Institute, the Computational Biology group at the Barcelona Supercomputing Center and the Germans Trias i Pujol Research Institute shows, for the first time, that within a tumor, the expression of the different hallmarks of cancer is not cell-specific, but rather position-specific.

30 Jan 2025

Targeting MYCN and MDM2 offers new hope for cancer therapy

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.

29 Jan 2025

Weekly diabetes injection could replace daily shots for lipodystrophy patients

Rutgers Health researchers have found that a weekly injection of diabetes medication could replace painful daily hormone shots for people with a rare genetic form of lipodystrophy that leaves patients with almost zero fat tissue, according to a study in The New England Journal of Medicine.

29 Jan 2025

Exploring the interaction between cell death and cellular senescence in cancer

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing.

29 Jan 2025

WHO voices concern over HIV program funding pause

The World Health Organization (WHO) expresses deep concern on the implications of the immediate funding pause for HIV programmes in low- and middle-income countries.

29 Jan 2025

New treatment identified for peripheral nerve sheath tumors

A multicenter collaboration led by the Bellvitge Biomedical Research Institute (IDIBELL) - Institut Català d'Oncologia (ICO) and the Germans Trias i Pujol Research Institute (IGTP) identified a potential new treatment for an aggressive sarcoma arising in the nerves.

28 Jan 2025

Asymptomatic brain metastasis in stage 4 breast cancer requires reevaluation of screening guidelines

A new study led by researchers at Moffitt Cancer Center shows that asymptomatic brain metastasis is more common in stage 4 breast cancer patients than previously believed.

28 Jan 2025

Microbial compound offers hope for vitiligo treatment

A natural compound derived from gut-friendly bacteria significantly slows the progression of vitiligo and may restore pigmentation, reports a new Northwestern University pre-clinical study in mice.

28 Jan 2025