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UVA research sheds light on how cancer remodels our chromosomes

Cancer remodels the architecture of our chromosomes so the disease can take hold and spread, researchers at the University of Virginia have revealed.

27 Oct 2020

Scientists use new approach to chart the spread of drug-resistant hospital bacteria

Scientists have used genome sequencing to reveal the extent to which a drug-resistant gastrointestinal bacterium can spread within a hospital, highlighting the challenge hospitals face in controlling infections.

27 Oct 2020

Scientists identify new therapeutic targets for SARS-CoV-2

To identify new potential therapeutic targets for SARS-CoV-2, a team of scientists at the New York Genome Center, New York University, and the Icahn School of Medicine at Mount Sinai, performed a genome-scale, loss-of-function CRISPR screen to systematically knockout all genes in the human genome.

27 Oct 2020

Research shows wrinkled 'super pea' may reduce risk of type 2 diabetes

A type of wrinkled 'super pea' may help control blood sugar levels and could reduce the risk of type 2 diabetes, suggests a new study.

27 Oct 2020

Cellular senescence variations may control health and onset of age-related diseases

Researchers from Kumamoto University, Japan have proposed that cellular senescence variations during the aging process could lead to control of health and onset of age-related diseases.

27 Oct 2020

Study finds new transposon-derived genes related to autism

The lack of some genes in the BEC/TCEAL cluster could be related to some alterations associated with the autism spectrum disorder, according to a preclinical study published in the journal Genome Biology, and led by Professor Jordi Garcia Fernàndez, from the Faculty of Biology and the Institute of Biomedicine of the University of Barcelona, and researcher Jaime Carvajal, from the Andalusian Centre for Developmental Biology - University Pablo de Olavide.

27 Oct 2020

Study analyzes link between clonal hematopoiesis and treatment-related blood cancer risk

In recent years, improvements in cancer therapy have led to a significant increase in cancer survivorship. Experts estimate that by 2022, the United States will have 18 million cancer survivors, but a subset of those survivors will have long-term health problems to be addressed.

27 Oct 2020

Study suggests 5’UTR of SARS-CoV-2 might be of pangolin coronavirus origin

Findings from a new genomic sequencing study support the hypothesis that the pangolin was the intermediate host for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that enabled transmission of the virus to humans.

26 Oct 2020

Research uncovers SARS-CoV-2 viral traits critical for the virus in human airways

A new study published on the preprint server bioRxiv* in October 2020 reports the discovery of important viral genomic features that are crucial to its replication in the human airway cells, and its enhancing mutations which increase the rate of replication and determine its target cells.

26 Oct 2020

Bruker introduces Vutara™ VXL best-in-class super-resolution microscope and spatial biology analysis capabilities

Bruker Corporation today announced the release of the Vutara VXL Super-Resolution Fluorescence Microscope for nanoscale biological imaging. The new system opens an affordable and easy-to-use path for both core facilities and individual investigators to enter the world of super-resolution imaging by incorporating Bruker’s industry-leading single-molecule localization (SML) technology in a streamlined system with compact footprint.

From Bruker Nano Surfaces and Metrology 23 Oct 2020

Researchers create AI system that matches tumors to best drug combinations

Only 4 percent of all cancer therapeutic drugs under development earn final approval by the U.S. Food and Drug Administration (FDA).

23 Oct 2020

Researchers use viral signatures to reveal transmission patterns of SARS-CoV-2

The coronavirus, responsible for the COVID-19 pandemic, has one official name--SARS-CoV-2. But according to virologists, mutations lead to hundreds of genetically-distinct versions of the virus.

23 Oct 2020

Congress should clarify limits of gene-editing technologies, says law professor

Genome editing of human embryos represents one of the most contentious potential scientific applications today. But what if geneticists could sidestep the controversy by editing sperm and eggs instead?

22 Oct 2020

SARS-CoV-2 mutations dictate severity of COVID-19 disease

A recent study by researchers from Semmelweis University and Pazmany Peter Catholic University in Budapest, Hungary, published on the preprint server medRxiv in October 2020, shows the relationship of specific mutations on the disease's outcome.

22 Oct 2020

Moffitt researchers find immune-oncologic differences in prostate tumors of African American men

Prostate cancer is the most common type of cancer among American men after skin cancer, but the disease does not affect all races equally.

21 Oct 2020

SARS-CoV-2 mutations possibly making virus less virulent

In their bioRxiv* preprint paper, the researchers focus on mapping the clade-specific mutations' effects on the protein structures' conformation and stability. They identified the mutations in the set of seven proteins - orf8, nsp2, nsp4, nsp6, nucleocapsid protein (N), and Spike protein (S).

21 Oct 2020

New DNA-cutting tool could advance gene editing for novel treatments

Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more quickly with a new tool for cutting larger pieces of DNA out of a cell's genome, according to a new study by UC San Francisco scientists.

21 Oct 2020

Study indicates the relationship between SARS-CoV-2 viral infection and diabetes

It has recently been described that infection by some enteroviruses - a genus of viruses that commonly cause diseases of varying severity - could potentially trigger diabetes, although its direct effect 'in vivo' as well as its mechanism of action at the molecular level were unknown.

21 Oct 2020

Researchers find distinct effects of adversity in the genomes of men than women born preterm

Researchers at McMaster University have found distinct effects of adversity early in life in the genomes of men compared to women who were born extremely preterm.

21 Oct 2020

Scientists show why zebra finches have problems with reproduction

In birds and other species alike, pairs can face considerable difficulties with reproduction. Scientists at the Max Planck Institute for Ornithology in Seewiesen have now shown in an extensive analysis of 23,000 zebra finch eggs that infertility is mainly due to males, while high embryo mortality is more a problem of the females.

20 Oct 2020

Genomic News and Research

UVA research sheds light on how cancer remodels our chromosomes

Scientists use new approach to chart the spread of drug-resistant hospital bacteria

Scientists identify new therapeutic targets for SARS-CoV-2

Research shows wrinkled 'super pea' may reduce risk of type 2 diabetes

Cellular senescence variations may control health and onset of age-related diseases

Study finds new transposon-derived genes related to autism

Study analyzes link between clonal hematopoiesis and treatment-related blood cancer risk

Study suggests 5’UTR of SARS-CoV-2 might be of pangolin coronavirus origin

Research uncovers SARS-CoV-2 viral traits critical for the virus in human airways

Bruker introduces Vutara™ VXL best-in-class super-resolution microscope and spatial biology analysis capabilities

Researchers create AI system that matches tumors to best drug combinations

Researchers use viral signatures to reveal transmission patterns of SARS-CoV-2

Congress should clarify limits of gene-editing technologies, says law professor

SARS-CoV-2 mutations dictate severity of COVID-19 disease

Moffitt researchers find immune-oncologic differences in prostate tumors of African American men

SARS-CoV-2 mutations possibly making virus less virulent

New DNA-cutting tool could advance gene editing for novel treatments

Study indicates the relationship between SARS-CoV-2 viral infection and diabetes

Researchers find distinct effects of adversity in the genomes of men than women born preterm

Scientists show why zebra finches have problems with reproduction

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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