Molecule News and Research

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Discover, Visualize and Identify Biomarkers

In this interview, Lucy Woods from Bruker Daltonics talks to News-Medical Life Sciences about the new MetaboScape to help identify and discover more biomarkers.

From Bruker Daltonics 10 Mar 2021

Researchers confirm new drug development route for treating multiple sclerosis, asthma

Brazilian researchers who study a native venomous fish have confirmed a route to drug development for the treatment of chronic inflammatory diseases such as multiple sclerosis and asthma.

10 Mar 2021

RNA editing events influence gene expression and phenotypic manifestation

Combining computational mining of big data with experimental testing in the lab, researchers at Children's Hospital of Philadelphia (CHOP) have identified RNA editing events that influence gene expression and, in turn, the phenotypic manifestation of that expression.

10 Mar 2021

PRRT technology may offer new treatment approaches for neuroendocrine tumors

Neuroendocrine tumors are cancers that begin in specialized cells called neuroendocrine cells. These cells have traits similar to those of nerve cells and hormone-producing cells.

9 Mar 2021

Project Helios launched to unlock new approaches in small molecule drug discovery

The University of Texas MD Anderson Cancer Center's Therapeutics Discovery division and Orionis Biosciences today announced the launch of Project Helios, a research collaboration designed to unlock new drug development opportunities through genome-scale mapping of drug-target interactions.

9 Mar 2021

Princeton researchers discover previously unknown organelle that plays role in bone metastasis

Some of Princeton's leading cancer researchers were startled to discover that what they thought was a straightforward investigation into how cancer spreads through the body -- metastasis -- turned up evidence of liquid-liquid phase separations: the new field of biology research that investigates how liquid blobs of living materials merge into each other, similar to the movements seen in a lava lamp or in liquid mercury.

9 Mar 2021

Scientists develop RNA-based therapeutic strategy for Charcot-Marie Tooth disease

Charcot-Marie Tooth disease is the most common hereditary neurological disease in the world. It affects the peripheral nerves and causes progressive paralysis of the legs and hands.

9 Mar 2021

Parkinson’s UK, University of Sheffield to develop new Parkinson’s drug

Parkinson's UK, the largest charitable funder of Parkinson's research in Europe, is investing up to £1.2 million into a pioneering one-year project in partnership with the University of Sheffield.

9 Mar 2021

New technique helps image biological samples at the microscopic level

Researchers have developed a spectroscopic microscope to enable optical measurements of molecular conformations and orientations in biological samples. The novel measurement technique allows researchers to image biological samples at the microscopic level more quickly and accurately.

9 Mar 2021

New biosensor measures extracellular hydrogen peroxide levels with nanometer-resolution

Several processes in the human body are regulated by biochemical reactions involving hydrogen peroxide (H2O2).

8 Mar 2021

CAR T-cell therapy triples expected length of remission for relapsed multiple myeloma patients

A new type of CAR T-cell therapy more than triples the expected length of remission for multiple myeloma patients who have relapsed several times, according to an international clinical trial with UT Southwestern as the lead enrolling site.

8 Mar 2021

Narrowing down on small molecular inhibitors of SARS-CoV-2 key protease

A recent methodological study by researchers from the University of Luxembourg shows that the combination of virtual screening approaches, molecular dynamics simulations and machine learning can substantially facilitate small molecule screening investigations targeted at key SARS-CoV-2 viral proteins.

8 Mar 2021

New, efficient method facilitates antibody development

In recent years, therapeutic antibodies have transformed the treatment of cancer and autoimmune diseases.

5 Mar 2021

SARS-CoV-2 escapes host immune responses by modulating dendritic cell maturation

A team of scientists from Italy and the USA has recently explored the maturation pattern of conventional dendritic cells (cDCs) during SARS-CoV-2 infection.

5 Mar 2021

Aptamer Group Extends Collaboration With Leading Biopharmaceutical Company to Explore Next-Generation Drug Delivery Approaches

Aptamer Group, the developer of Optimer™ reagents and therapeutics, today announced the extension of their current agreement with AstraZeneca, a global biopharmaceutical company. Image credit: Shutterstock.com/Billion Photos

From Aptamer Group 5 Mar 2021

Identification of neutralizing IFNL3 autoantibodies in severe COVID-19 cases

Scientists have recently developed a novel alternative molecular display technology called Molecular Indexing of Proteins by Self Assembly (MIPSA). Their research explains how this technology overcomes the critical disadvantages of PLATO and other full-length protein array technologies.

5 Mar 2021

Compound isolated from Moroccan fungus shows promise to fight triple negative breast cancer

A compound isolated from a fungus growing on the roots of a flowering plant in Morocco shows promise as a powerful opponent of aggressive triple negative breast cancer, scientists say.

4 Mar 2021

Study identifies potential therapeutic target for non-alcoholic fatty liver disease

An international team of researchers has identified the CNNM4 protein as a key regulator of magnesium in the liver and potential therapeutic target for non-alcoholic fatty liver disease, according to a study published in the Journal of Hepatology.

4 Mar 2021

Study reveals a small molecule inhibits SARS-CoV-2 infection in cells

Researchers found a small molecule that inhibits different virus proteins and significantly reduces infection in cells. Combined with the antiviral remdesivir, its potency increases significantly, suggesting it may be a potential antiviral candidate for the treatment of COVID-19.

4 Mar 2021

Cell surface marker CD47 may allow early diagnosis of severe COVID-19

A new study reports the potential of the cell surface marker, CD47, as a biomarker for hyperinflammation, a characteristic feature of severe COVID-19.

4 Mar 2021

Molecule News and Research

Discover, Visualize and Identify Biomarkers

Researchers confirm new drug development route for treating multiple sclerosis, asthma

RNA editing events influence gene expression and phenotypic manifestation

PRRT technology may offer new treatment approaches for neuroendocrine tumors

Project Helios launched to unlock new approaches in small molecule drug discovery

Princeton researchers discover previously unknown organelle that plays role in bone metastasis

Scientists develop RNA-based therapeutic strategy for Charcot-Marie Tooth disease

Parkinson’s UK, University of Sheffield to develop new Parkinson’s drug

New technique helps image biological samples at the microscopic level

New biosensor measures extracellular hydrogen peroxide levels with nanometer-resolution

CAR T-cell therapy triples expected length of remission for relapsed multiple myeloma patients

Narrowing down on small molecular inhibitors of SARS-CoV-2 key protease

New, efficient method facilitates antibody development

SARS-CoV-2 escapes host immune responses by modulating dendritic cell maturation

Aptamer Group Extends Collaboration With Leading Biopharmaceutical Company to Explore Next-Generation Drug Delivery Approaches

Identification of neutralizing IFNL3 autoantibodies in severe COVID-19 cases

Compound isolated from Moroccan fungus shows promise to fight triple negative breast cancer

Study identifies potential therapeutic target for non-alcoholic fatty liver disease

Study reveals a small molecule inhibits SARS-CoV-2 infection in cells

Cell surface marker CD47 may allow early diagnosis of severe COVID-19

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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