Pathology News and Research

RSS

Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Improving the efficiency of antiangiogenic and antifibrotic drug for treatment of lung cancer

The University of Barcelona and Hospital Clínic de Barcelona collaborate with Boehringer Ingelheim Inc. to improve the efficiency of nintedanib, an antiangiogenic and antifibrotic drug, for the treatment of lung cancer.

19 Nov 2019

Researchers discover new pathway to 'reprogram' killer cells

Killer cells of the immune system detect and kill infected cells or cancer cells. Researchers at the Institute of Pathology at the University of Bern have now discovered that the mechanism by which certain immune cells kill their target cells can also be used to control the killer cells themselves.

19 Nov 2019

New analytical framework for analyzing nonstandardized stress echocardiography sequences

Echocardiography is a test that uses ultrasound techniques to produce images of the heart in real time. Stress echocardiography uses this technique to evaluate the heart rate response while performing an activity in which the heart has to work (stress).

19 Nov 2019

Self-destructive mitochondria may set the stage for neurodegeneration in ALS

Northwestern Medicine scientists have discovered a new phenomenon in the brain that could explain the development of early stages of neurodegeneration seen in diseases such as ALS, which affects voluntary muscle movement such as walking and talking.

18 Nov 2019

CSU awarded $1.2 million subcontract to accelerate tuberculosis vaccine development

A team of researchers in the Department of Microbiology, Immunology and Pathology at Colorado State University aim to advance what is known about the complex immune response necessary to prevent tuberculosis disease.

15 Nov 2019

UCI researchers develop new cell therapy to improve memory, prevent seizures after TBI

Researchers from the University of California, Irvine developed a breakthrough cell therapy to improve memory and prevent seizures in mice following traumatic brain injury.

15 Nov 2019

Scientists reverse learning and memory deficits with drugs in animal model of Down syndrome

In a surprising finding using the standard animal model of Down syndrome (DS), scientists were able to correct the learning and memory deficits associated with the condition -- the leading genetic cause of cognitive disability and the most frequently diagnosed chromosomal disorder in the U.S. -- with drugs that target the body's response to cellular stresses.

15 Nov 2019

AI-powered CAD software can reduce bias in radiology reports, study finds

A study by the Centre for Advanced Research in Imaging, Neuroscience and Genomics found that AI powered CAD software can reduce hedging and defensive reporting statements in radiologist reports, resulting in clearer more actionable diagnosis descriptions.

15 Nov 2019

New insights into how immune system and inflammation play a role in PD

Relatively new research findings indicating that the earliest stages of Parkinson's disease (PD) may occur in the gut have been gaining traction in recent years. In a review published in the Journal of Parkinson's Disease, Tomasz Brudek, PhD, evaluates evidence for the association between inflammatory bowel disease (IBD) and PD and proposes directions for future research.

14 Nov 2019

Promising method to identify aggressive breast cancers that will respond to immunotherapy

University of North Carolina Lineberger Comprehensive Cancer Center researchers have discovered a promising method to identify aggressive breast cancer tumors that will respond to drugs that unleash the immune system against cancer.

14 Nov 2019

Clinical analysis reveals high expression of apoptosis protein in chemoresistant TNBC

78 TNBC biopsies from patients with different responses to chemotherapy were analysed for API-5 expression before any treatment.

13 Nov 2019

Johns Hopkins launches new center for 'immunoengineering' research

If the saying that two heads are better than one is true, then joining two fields of science may be better than one to spur more advances in medicine.

13 Nov 2019

TSU researchers develop new approach to diagnose adenocarcinoma

Scientists have developed a new approach to the diagnosis of adenocarcinoma - a malignant tumor of the prostate gland. Artificial intelligence is used to determine oncopathology and determine the stage of the disease with this approach.

13 Nov 2019

Standard methods not adequate to detect prosthetic joint infections in rheumatic disease patients

Standard diagnostic methods are not adequate to identify prosthetic joint infections in patients with rheumatic diseases, according to findings from a new study by researchers from Hospital for Special Surgery in New York City.

12 Nov 2019

First comprehensive characterization of blood-brain, blood-tumor barriers in brain metastases

The human brain has some remarkable capabilities - including the ability to block cancer drugs from effectively reaching cancer cells in the brain.

12 Nov 2019

Contraceptive drug effective in preventing and regressing cervical cancer in mice

A new study in The American Journal of Pathology, published by Elsevier, reports that medroxyprogesterone acetate (MPA), the active ingredient in the common contraceptive injection Depo-Provera, was effective in preventing the development of cervical cancer in mice with precancerous lesions.

12 Nov 2019

Rutgers researcher receives $600,000 grant to study chronic lymphocytic leukemia

Rutgers Cancer Institute of New Jersey researcher Hossein Khiabanian, PhD, has received a $600,000 Translational Award from the V Foundation for Cancer Research to study chronic lymphocytic leukemia with the aim of developing research models that may help investigators better understand how CLL cells are influenced by new therapies.

11 Nov 2019

Toddlers with fewer spoken words have more frequent, severe temper tantrums

Toddler speech delays and temper tantrums have long been assumed to go hand in hand, but no large-scale research had successfully backed up that assumption with data.

11 Nov 2019

New recommendations aim to improve outcomes of Parkinson's disease patients

Since the discovery that the gut microbiome may play a role in the development of Parkinson's disease (PD), this fresh scientific approach has produced varying results. In this review published in the Journal of Parkinson's Disease scientists compare results of current research and provide recommendations to increase the comparability and utility of these studies with a view towards improving patient outcomes.

11 Nov 2019

Zika virus causes altered immune responses and brain abnormalities in healthy pig offspring

Zika virus infection in the womb produces altered immune responses and sex-specific brain abnormalities in apparently healthy pig offspring, according to a study published November 14 in the open-access journal PLOS Pathogens by Uladzimir Karniychuk of the University of Saskatchewan, and colleagues.

From PLOS ONE 11 Nov 2019

Pathology News and Research

Further Reading

Improving the efficiency of antiangiogenic and antifibrotic drug for treatment of lung cancer

Researchers discover new pathway to 'reprogram' killer cells

New analytical framework for analyzing nonstandardized stress echocardiography sequences

Self-destructive mitochondria may set the stage for neurodegeneration in ALS

CSU awarded $1.2 million subcontract to accelerate tuberculosis vaccine development

UCI researchers develop new cell therapy to improve memory, prevent seizures after TBI

Scientists reverse learning and memory deficits with drugs in animal model of Down syndrome

AI-powered CAD software can reduce bias in radiology reports, study finds

New insights into how immune system and inflammation play a role in PD

Promising method to identify aggressive breast cancers that will respond to immunotherapy

Clinical analysis reveals high expression of apoptosis protein in chemoresistant TNBC

Johns Hopkins launches new center for 'immunoengineering' research

TSU researchers develop new approach to diagnose adenocarcinoma

Standard methods not adequate to detect prosthetic joint infections in rheumatic disease patients

First comprehensive characterization of blood-brain, blood-tumor barriers in brain metastases

Contraceptive drug effective in preventing and regressing cervical cancer in mice

Rutgers researcher receives $600,000 grant to study chronic lymphocytic leukemia

Toddlers with fewer spoken words have more frequent, severe temper tantrums

New recommendations aim to improve outcomes of Parkinson's disease patients

Zika virus causes altered immune responses and brain abnormalities in healthy pig offspring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News