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Precision epidemiology could help explain variability in COVID-19 symptoms

Researchers from National Taiwan University have presented a multi-omics view of how mutations in angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2) affect infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and progression of coronaviruses disease 2019 (COVID-19).

20 Oct 2020

Cell nucleus may play role in enabling cells to evade crowded environments

Like people, cells in the human body protect their personal space. They seem to know how much space they need, and if it gets too tight, most cells prefer to break free.

19 Oct 2020

Novel multimodal intervention improves physical fitness and cognitive function

Researchers studied the effects of a 12-week exercise regimen on 148 active-duty Air Force airmen, half of whom also received a twice-daily nutrient beverage that included protein; the omega-3 fatty acid, DHA; lutein; phospholipids.

19 Oct 2020

A novel species of bacteria isolated from diseased walnut discovered in Portugal

Xanthomonas euroxanthea, a new species of bacteria isolated from diseased walnut discovered in Portugal.Bacteria recently isolated from walnut (Juglans regia L.) buds in Portugal has been identified as a new species of Xanthomonas.

19 Oct 2020

Concerti algorithm identifies intra-patient heteroplasmies in SARS-CoV-2 patients

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus that emerged in Wuhan, China, in late 2019 has caused the ongoing coronavirus disease 2019 (COVID-19) pandemic, which has affected more than 39.8 million lives globally and claimed over 1.11 million deaths to date.

18 Oct 2020

Comparative analysis reveals common vulnerabilities across coronaviruses

Three lethal human respiratory syndromes associated with coronavirus (CoV) infections have emerged in the past two decades. They are severe acute respiratory syndrome (SARS) in 2002, Middle East respiratory syndrome (MERS) in 2012, and coronavirus disease 2019 (COVID-19) in 2019.

18 Oct 2020

Gene variants may provide clues to successful treatment of pediatric eosinophilic esophagitis

A group of three gene variants, commonly inherited together, may provide clues to more successful treatment of pediatric eosinophilic esophagitis (EoE), a chronic inflammation of the food pipe often confused with gastroesophageal reflux disease (GERD).

16 Oct 2020

Cloud-based tool can rapidly detect and track emerging pathogens

Published today in the journal GigaScience is a new open source, cloud-based tool called IDseq that makes it possible to rapidly detect, identify, and track emerging pathogens such as SARS-CoV-2.

15 Oct 2020

Genomic analysis of neuroblastoma sheds light on childhood solid tumors

Researchers have used insight from a comprehensive genomic analysis of neuroblastoma to learn about the process driving one of the most common childhood solid tumors. The findings revealed possible approaches for developing precision medicines to improve patient outcomes. St. Jude Children's Research Hospital scientists led the study, which appears today in the journal Nature Communications.

15 Oct 2020

New saliva tests can enable early detection and diagnosis of COVID-19, head & neck cancer

Summit Biolabs, Inc., an early-stage molecular diagnostics company specializing in saliva-based testing for COVID-19 and head & neck cancer, and the Colorado Center for Personalized Medicine (CCPM) at the University of Colorado Anschutz Medical Campus announced today a broad strategic collaboration involving research, development and commercialization of saliva liquid-biopsy tests for early cancer detection and diagnosis of COVID-19 and other viral contagions.

15 Oct 2020

Researchers use AI methods to 'redefine' Alzheimer's disease

As the search for successful Alzheimer's disease drugs remains elusive, experts believe that identifying biomarkers -- early biological signs of the disease -- could be key to solving the treatment conundrum.

14 Oct 2020

Alternate primers for whole-genome SARS-CoV-2 sequencing

A new study published on the preprint server bioRxiv* in October 2020 describes the gap frequencies and positions in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome and a set of alternative primers with a sequencing scheme to provide better genomic coverage and quality.

14 Oct 2020

First confirmed US case of SARS-CoV-2 reinfection

Of the cases of reinfections worldwide, a particular case has been reported by scientists at the Nevada Institute of Personalized Medicine, University of Nevada. A 25-year-old man from Washoe County in the United States, the hardest-hit country globally, has more than 7.85 million cases.

14 Oct 2020

EuCanImage to build scalable cancer imaging platform for next-generation artificial intelligence in oncology

EuCanImage has been launched. This project from the Horizon 2020 program is coordinated by Karim Lekadir, Ramón y Cajal postdoctoral researcher at the Faculty of Mathematics and Computer Science.

13 Oct 2020

Neoadjuvant trial of combination immunotherapy has favorable outcomes in bladder cancer patients

Neoadjuvant, or pre-surgical, combination treatment with the immune checkpoint inhibitors tremelimumab (anti-CTLA-4) and durvalumab (anti-PD-1) was well-tolerated and showed early signs of activity in certain patients with localized bladder cancer who do not have standard treatment options available, according to a Phase I clinical trial conducted by The University of Texas MD Anderson Cancer Center.

13 Oct 2020

Study elucidates the role of ERβ in growth of skeletal muscle in female mice

Researchers at Kumamoto University, Japan generated mice lacking the estrogen receptor beta (ERβ) gene, both fiber-specific and muscle stem cell-specific, which resulted in abnormalities in the growth and regeneration of skeletal muscle in female mice.

12 Oct 2020

Genomic News and Research

Precision epidemiology could help explain variability in COVID-19 symptoms

Cell nucleus may play role in enabling cells to evade crowded environments

Novel multimodal intervention improves physical fitness and cognitive function

A novel species of bacteria isolated from diseased walnut discovered in Portugal

Concerti algorithm identifies intra-patient heteroplasmies in SARS-CoV-2 patients

Comparative analysis reveals common vulnerabilities across coronaviruses

Gene variants may provide clues to successful treatment of pediatric eosinophilic esophagitis

Cloud-based tool can rapidly detect and track emerging pathogens

Genomic analysis of neuroblastoma sheds light on childhood solid tumors

New saliva tests can enable early detection and diagnosis of COVID-19, head & neck cancer

Researchers use AI methods to 'redefine' Alzheimer's disease

Alternate primers for whole-genome SARS-CoV-2 sequencing

First confirmed US case of SARS-CoV-2 reinfection

EuCanImage to build scalable cancer imaging platform for next-generation artificial intelligence in oncology

Neoadjuvant trial of combination immunotherapy has favorable outcomes in bladder cancer patients

Study elucidates the role of ERβ in growth of skeletal muscle in female mice

CHLA investigator receives $3.4 million research grant to study rotavirus vaccine

NIH provides $9.3 million grant to create new Center for Precision Animal Modeling at UAB

Findings could bring hope for novel therapeutic strategies against malaria

Genomic study shows the evolutionary history of banyan trees and their wasp pollinators

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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