Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Genervon reports new findings that drug candidate GM6 attenuates Alzheimer's disease in mice model

Following the closure of several research programs for Alzheimer's disease, in early 2018 the FDA issued a release entitled "Draft Guidance for Industry: Early Alzheimer's Disease: Developing Drugs for Treatment." Encouraged by the proposed changes in the new guidance, Genervon's research team reported new findings that its drug candidate GM6 attenuates Alzheimer's disease in an early AD transgenic APP mice model.

25 Sep 2018

Researchers find molecule that halts, reverts neurodegeneration caused by Parkinson's disease

The small SynuClean-D molecule interrupts the formation of the alpha-synuclein amyloid fibers responsible for the onset of Parkinson's disease, and reverts the neurodegeneration caused by the disease.

25 Sep 2018

Study explores link between genetic predisposition to Alzheimer's and cardiometabolic risk factors

Alzheimer's disease is the most common memory disorder. In addition to genetic predisposition, the risk of Alzheimer's disease is also increased by cardiometabolic risk factors, such as type 2 diabetes. The accumulation of these risk factors is known as the metabolic syndrome.

25 Sep 2018

Physical activity may have beneficial effects for people with rare Alzheimer's disease

For individuals carrying a genetic mutation that causes Alzheimer's disease, engaging in at least 2.5 hours of physical activity per week may have beneficial effects on markers of Alzheimer's disease brain changes and may delay cognitive decline, according to a new study available online by Alzheimer's & Dementia: The Journal of the Alzheimer's Association as an article in press, corrected proof.

25 Sep 2018

Toxicological evaluation and dosimetry estimation of potential PET radiotracer

The SR101 N-(3-[18F]Fluoropropyl) sulfonamide ([18F]SRF101) is a Sulforhodamine 101 derivative that was previously synthesized by our group.

25 Sep 2018

New research finds link between impaired vision, hearing, and cognition

Experts at a prestigious medical conference hosted by the American Geriatrics Society and funded by the National Institute on Aging hope their work--reported today in the Journal of the American Geriatrics Society--will have colleagues seeing eye-to-eye on an important but under-researched area of health care: The link between impaired vision, hearing, and cognition

25 Sep 2018

Blood-brain barrier can be important biomarker for early diagnosis of Alzheimer's disease

USC scientists say Alzheimer's could be diagnosed earlier if scientists focus on an early warning within the brain's circulation system.

25 Sep 2018

Biogen and Eisai announce results of LTE Phase 1b study of aducanumab for treating MCI

Biogen and Eisai Co., Ltd. announced results from a recent analysis of the ongoing long-term extension Phase 1b study of aducanumab, an investigational treatment for mild cognitive impairment due to Alzheimer's disease and mild AD dementia.

24 Sep 2018

Cytox, AIBL announce expanded agreement to assess genetic risk for Alzheimer’s

Cytox, a precision medicine company which today is commercializing polygenic risk scoring approaches for assessing genetic risk for developing Alzheimer's disease and other neurological diseases, has announced it has expanded its research collaboration with the Australian Imaging, Biomarker & Lifestyle Flagship Study of Ageing to test new algorithms for identifying the pre-symptomatic and mild cognitively impaired people most at risk to progress to AD.

24 Sep 2018

Study sheds light on molecular mechanisms underlying progression of prion diseases

A new study has shed light on the mechanisms underlying the progression of prion diseases and identified a potential target for treatment.

21 Sep 2018

Survey estimates caregiving costs for family members

"Informal care" is the term used in medicine to describe unpaid care provided by family and friends. It's an important lifeline for millions of older adults in the U.S. who need day-to-day help with shopping, cooking, cleaning, eating, taking medicine, looking after their own daily well-being, and many other activities essential to our health and quality of life as we age.

21 Sep 2018

USC research uncovers previously unknown genetic risk factor for dementia

New research from USC has uncovered a previously unknown genetic risk factor for Alzheimer's disease and related dementias. The study provides insights on how these conditions, and other diseases of aging, might one day be treated and prevented.

21 Sep 2018

Study explores connection between sexuality and cognitive status in older adults

The number of people who live at home with Alzheimer's Disease (AD), a brain disease that causes abnormal changes that kill brain cells, is expected to grow from 3.2 million today to more than 8 million in 2050.

21 Sep 2018

Air pollution appears to be linked to increased risk of developing dementia

According to a new study co-authored by Professor Frank Kelly, School of Population Health & Environmental Sciences, air pollution appears to be linked to an increased risk of developing dementia.

21 Sep 2018

First evaluation of benefits, harms of Alzheimer's screening for family members of older adults

With the support of a new $3 million, five-year National Institute on Aging grant, researchers from the Regenstrief Institute and Indiana University Center for Aging Research are conducting the first evaluation of the benefits and harms of Alzheimer's disease screening for family members of older adults.

20 Sep 2018

Alzheimer’s diagnosis might become simpler with new brain imaging method

Accurate diagnosis of Alzheimer’s disease may be difficult in most patients as similar symptoms can be seen in several other disease conditions as well.

20 Sep 2018

Air pollution increases risk of dementia

A new study has shown that air pollution raises the risk of dementia. The risk remains among people of all ages find researchers.

18 Sep 2018

Research finds physical connection between the brain's fluid reservoirs and meningeal lymphatics

PureTech Health plc, an advanced biopharmaceutical company developing novel medicines for dysfunctions of the Brain-Immune-Gut Axis, today notes the publication of research in Nature Neuroscience that identifies the physical connection between the brain's fluid reservoirs and the meningeal lymphatics, through which immune cells traffic out of the central nervous system.

18 Sep 2018

Amyloid β protein makes comeback as therapeutic target for Alzheimer's disease

For many years amyloid β protein was considered to be a promising therapeutic target in Alzheimer's disease but, for a long time, research results were very disappointing.

18 Sep 2018

Hospitalization after antibiotic initiation found to be higher for people with Alzheimer’s disease

Persons with Alzheimer's disease are more often hospitalized after antibiotic initiation than people without AD, a new study from the University of Eastern Finland shows.

18 Sep 2018

Alzheimer's Disease News and Research

Further Reading

Genervon reports new findings that drug candidate GM6 attenuates Alzheimer's disease in mice model

Researchers find molecule that halts, reverts neurodegeneration caused by Parkinson's disease

Study explores link between genetic predisposition to Alzheimer's and cardiometabolic risk factors

Physical activity may have beneficial effects for people with rare Alzheimer's disease

Toxicological evaluation and dosimetry estimation of potential PET radiotracer

New research finds link between impaired vision, hearing, and cognition

Blood-brain barrier can be important biomarker for early diagnosis of Alzheimer's disease

Biogen and Eisai announce results of LTE Phase 1b study of aducanumab for treating MCI

Cytox, AIBL announce expanded agreement to assess genetic risk for Alzheimer’s

Study sheds light on molecular mechanisms underlying progression of prion diseases

Survey estimates caregiving costs for family members

USC research uncovers previously unknown genetic risk factor for dementia

Study explores connection between sexuality and cognitive status in older adults

Air pollution appears to be linked to increased risk of developing dementia

First evaluation of benefits, harms of Alzheimer's screening for family members of older adults

Alzheimer’s diagnosis might become simpler with new brain imaging method

Air pollution increases risk of dementia

Research finds physical connection between the brain's fluid reservoirs and meningeal lymphatics

Amyloid β protein makes comeback as therapeutic target for Alzheimer's disease

Hospitalization after antibiotic initiation found to be higher for people with Alzheimer’s disease

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