Genes News and Research

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Researchers develop gene classifier to predict DCIS risk of cancer progression

A team of researchers mapping a molecular atlas for ductal carcinoma in situ (DCIS) has made a major advance toward distinguishing whether the early pre-cancers in the breast will develop into invasive cancers or remain stable.

20 Nov 2023

Avian influenza A H5N1 virus impacts wide range of wildlife in the U.S., study shows

Study highlights the spread of the highly pathogenic avian influenza A (H5N1) virus among non-domesticated animals in the U.S., revealing neurological symptoms as a key clinical presentation and expanding the range of species affected by this Eurasian lineage virus.

19 Nov 2023

Machine learning uncovers potent immunomodulators for vaccines and immunotherapy

Small molecules called immunomodulators can help create more effective vaccines and stronger immunotherapies to treat cancer.

17 Nov 2023

Micronutrient deficiencies linked to gut microbiome shifts and antibiotic resistance

University of B.C. researchers have uncovered startling connections between micronutrient deficiencies and the composition of gut microbiomes in early life that could help explain why resistance to antibiotics has been rising across the globe.

17 Nov 2023

Complex genetics behind human cranial vault shape revealed

Researchers at the University of Pittsburgh and KU Leuven have discovered a suite of genes that influence head shape in humans.

17 Nov 2023

Intensive pig farming linked to dangerous zoonotic pathogens, study warns

A recent study in PNAS reveals that the expansion of large-scale pig rearing has led to the emergence of novel, highly pathogenic Streptococcus suis strains, posing a potential zoonotic threat. The research highlights the critical need for monitoring and control strategies in the face of escalating livestock populations.

16 Nov 2023

Scientists uncover "genomic tug of war" that influences chemotherapy's effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

16 Nov 2023

New insights into how cells maintain their identity over generations

Every cell in the human body contains the same genetic instructions, encoded in its DNA. However, out of about 30,000 genes, each cell expresses only those genes that it needs to become a nerve cell, immune cell, or any of the other hundreds of cell types in the body.

16 Nov 2023

TACTIC project aims to uncover genetic causes of cancer and develop targeted therapies

Investigating the genetic causes of cancer and fighting them with new drugs: To this end, German Cancer Aid is funding the TACTIC project until 2028 with 11.8 million euros.

16 Nov 2023

AI model predicts patient outcomes across multiple cancer types

Investigators from the UCLA Health Jonsson Comprehensive Cancer Center have developed an artificial intelligence (AI) model based on epigenetic factors that is able to predict patient outcomes successfully across multiple cancer types.

16 Nov 2023

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study reveals that senolytics can reduce aging in human brain organoids and mitigate COVID-19 neuropathology, suggesting their potential as a therapeutic strategy against brain aging and coronavirus-related neurological complications.

15 Nov 2023

Longitudinal study elucidates mechanisms driving progression of neurodegenerative disorders

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 21, entitled, "Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model."

15 Nov 2023

New study investigates role of rare gene variants in IBD risk for African Americans

The advent of whole genome sequencing technology has prompted an explosion in research into how genetics are associated with disease risk.

15 Nov 2023

Research opens the door to a potential treatment strategy for certain advanced prostate cancers

Epigenetic changes can cause prostate cancer to resist treatment by switching genes on or off. One epigenetic mechanism tags genes with DNA methylation marks.

15 Nov 2023

Study sheds light on specific variants responsible for rare and serious disorder

Many disorders are caused by genetic variants; to make matters worse, the genetic origin of most disorders remains unknown.

15 Nov 2023

Investigating the link between gut inflammation, aging, and Alzheimer's disease

A recent study in discusses how gut inflammation is associated with age and Alzheimer's disease.

15 Nov 2023

New research explores the unique effects of ADHD medications on Drosophila brain cells

The effect of two drugs used for the treatment of attention-deficit/hyperactivity disorder.

15 Nov 2023

New approach to CAR T cell therapy may extend treatment effectiveness

CAR T cell therapy, a powerful type of immunotherapy, has begun to revolutionize cancer treatment. Pioneered at Memorial Sloan Kettering Cancer Center (MSK), the therapy involves engineering a patient's T cells so they recognize and attack cancer cells.

14 Nov 2023

Study reveals mechanisms underlying non-suppressible HIV viremia

Human immunodeficiency virus (HIV) works by entering specific immune cells and replicating inside them.

14 Nov 2023

Circular extrachromosomal DNA identified as a potential target for new medulloblastoma therapies

A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA - loops of DNA found outside of regular chromosomes - are twice as likely to relapse and three times as likely to die within five years of diagnosis.

14 Nov 2023

Genes News and Research

Researchers develop gene classifier to predict DCIS risk of cancer progression

Avian influenza A H5N1 virus impacts wide range of wildlife in the U.S., study shows

Machine learning uncovers potent immunomodulators for vaccines and immunotherapy

Micronutrient deficiencies linked to gut microbiome shifts and antibiotic resistance

Complex genetics behind human cranial vault shape revealed

Intensive pig farming linked to dangerous zoonotic pathogens, study warns

Scientists uncover "genomic tug of war" that influences chemotherapy's effectiveness

New insights into how cells maintain their identity over generations

TACTIC project aims to uncover genetic causes of cancer and develop targeted therapies

AI model predicts patient outcomes across multiple cancer types

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Longitudinal study elucidates mechanisms driving progression of neurodegenerative disorders

New study investigates role of rare gene variants in IBD risk for African Americans

Research opens the door to a potential treatment strategy for certain advanced prostate cancers

Study sheds light on specific variants responsible for rare and serious disorder

Investigating the link between gut inflammation, aging, and Alzheimer's disease

New research explores the unique effects of ADHD medications on Drosophila brain cells

New approach to CAR T cell therapy may extend treatment effectiveness

Study reveals mechanisms underlying non-suppressible HIV viremia

Circular extrachromosomal DNA identified as a potential target for new medulloblastoma therapies

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