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Scientists map genetic networks that control the biology of regulatory T cells

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed.

1 Oct 2020

Researchers uncover the cause of 1990s Argentina cholera epidemic

The evolution of epidemic and endemic strains of the cholera-causing bacterium Vibrio cholerae in Argentina has been mapped in detail by researchers at the Wellcome Sanger Institute, the London School of Hygiene and Tropical Medicine, the University of Cambridge and the INEI-ANLIS "Dr Carlos G. Malbrán", Argentina.

1 Oct 2020

In-depth analysis of coronavirus genome sequence in Norfolk identifies hidden outbreaks

An in-depth analysis of the genome sequence of coronavirus circulating in Norfolk, UK by researchers at the Quadram Institute and University of East Anglia has mapped the spread of the virus, identified hidden outbreaks and provided insights into the effectiveness of interventions to stop its spread.

1 Oct 2020

Patients with invasive lobular carcinoma could benefit from additional adjuvant therapy

New results presented at the 12th European Breast Cancer Conference show that a test, which looks at the activity of 70 genes in breast cancer tissue, is possible to use in the clinic to identify patients with invasive lobular carcinoma (ILC) that is at high risk of recurring and progressing.

1 Oct 2020

NIH-funded nationwide study seeks to discover the cause of rare forms of diabetes

A nationwide study funded by the National Institutes of Health will seek to discover the cause of several unusual forms of diabetes.

30 Sep 2020

PrimeStore® MTM novel viral transport media successfully evaluated by Public Health England for SARS-CoV-2 inactivation

EKF Diagnostics announces that the novel viral transport media PrimeStore® MTM has been successfully evaluated for effective SARS-CoV-2 inactivation.

From EKF Diagnostics 29 Sep 2020

UCLA researchers receive $13 million NIH grant to combat melanoma

UCLA researchers have received a $13 million grant from the National Institutes of Health to find new ways to overcome melanoma resistance to some of the most promising targeted therapies and immunotherapies.

28 Sep 2020

Brain wiring genes may be linked to a significant portion of cerebral palsy cases

In an article published in Nature Genetics, researchers confirm that about 14% of all cases of cerebral palsy, a disabling brain disorder for which there are no cures, may be linked to a patient's genes and suggest that many of those genes control how brain circuits become wired during early development.

28 Sep 2020

Mapping the evolutionary profile of SARS-CoV-2 and COVID-19 using mutation order approach

Several months into the COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), we still do not know much about the early evolutionary history and order of mutational events of the virus during this pandemic.

28 Sep 2020

CRISPR screening identifies human host pathways that facilitate coronavirus infection

The human coronavirus family consists of 7 known pathogens, for which there are no approved vaccines or specific therapeutic options. Although the seasonal human coronaviruses - OC43, HKU1, 229E, and NL63 – only cause mild respiratory infections, three highly pathogenic coronaviruses that emerged in the last two decades revealed the pandemic potential of this family of viruses.

27 Sep 2020

New study links 160 genes to brain shrinkage

A new study implicates 160 genes in brain shrinkage seen on MRIs of 45,000 healthy adults. The shrinkage is in the cortex, the dimply outer layer of the brain that gives rise to thinking, awareness and action, and largely consists of gray matter.

25 Sep 2020

Individuals with severe forms of COVID-19 disease can have compromised type I interferon responses

Individuals with severe forms of COVID-19 disease can present with compromised type I interferon (IFN) responses based on their genetics, according to results published in two papers today in the journal Science.

25 Sep 2020

Genetic variation not linked with differences in COVID-19 morbidity and mortality

A comprehensive search of genetic variation databases has revealed no significant differences across populations and ethnic groups in seven genes associated with viral entry of SARS-CoV-2.

24 Sep 2020

Prevalence of SARS-CoV-2 with D614G mutation in a second wave infection in Houston

A recent study reveals that the genetic variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detected in the initial phase of coronavirus disease 2019 (COVID-19) pandemic differ from the variants detected in a massive second wave of infection in Houston, Texas. The study is currently available on the medRxiv preprint server.

24 Sep 2020

Molecular analysis of COVID-19's second wave shows mutant viruses linked to rapid spread

Molecular analysis of COVID-19's powerful second wave in Houston – from May 12 to July 7 – shows a mutated virus strain linked to higher transmission and infection rates than the coronavirus strains that caused Houston's first wave.

24 Sep 2020

Study finds spectrum of genes responsible for inherited hearing loss in Israeli Jewish families

Until now, seven genes were known to be involved in hearing loss in Israel's Jewish population. A new study led by Zippora Brownstein, PhD, and Prof. Karen Avraham from the Sackler Faculty of Medicine at Tel Aviv University has found that 32 genes are responsible for inherited hearing loss in Israeli Jewish families.

23 Sep 2020

Study shows key genetic differences in ADHD between African American and Caucasian children

Researchers from Children's Hospital of Philadelphia have shown there may be key genetic differences in the causes of attention-deficit hyperactivity disorder between African Americans and people of European ancestry, which may play an important part in how patients of different ethnic backgrounds respond to treatments for this condition.

22 Sep 2020

Study reveals how people with retinal degenerative disease can maintain night vision

New insight on how people with retinal degenerative disease can maintain their night vision for a relatively long period of time has been published today in the open-access eLife journal.

22 Sep 2020

NAU researcher awarded $3.75 million NCI grant to build cancer research software

Greg Caporaso, director of the Center for Applied Microbiome Science, part of the Pathogen and Microbiome Institute at Northern Arizona University, has been awarded a $3.75 million grant by the National Cancer Institute to build software capable of analyzing and archiving data focused on the interplay between the human microbiome (the trillions of microorganisms living in and on the human body) and diverse types of cancer.

22 Sep 2020

New $6.2 million study seeks to define molecular linkages between aging and Parkinson's

A collaborative team between the University of Minnesota Medical School and Van Andel Institute will soon begin a $6.2 million study that seeks to define the molecular linkages between aging and Parkinson's disease -- an approach for new treatment targets not yet explored by many researchers.

21 Sep 2020

Genomic News and Research

Scientists map genetic networks that control the biology of regulatory T cells

Researchers uncover the cause of 1990s Argentina cholera epidemic

In-depth analysis of coronavirus genome sequence in Norfolk identifies hidden outbreaks

Patients with invasive lobular carcinoma could benefit from additional adjuvant therapy

NIH-funded nationwide study seeks to discover the cause of rare forms of diabetes

PrimeStore® MTM novel viral transport media successfully evaluated by Public Health England for SARS-CoV-2 inactivation

UCLA researchers receive $13 million NIH grant to combat melanoma

Brain wiring genes may be linked to a significant portion of cerebral palsy cases

Mapping the evolutionary profile of SARS-CoV-2 and COVID-19 using mutation order approach

CRISPR screening identifies human host pathways that facilitate coronavirus infection

New study links 160 genes to brain shrinkage

Individuals with severe forms of COVID-19 disease can have compromised type I interferon responses

Genetic variation not linked with differences in COVID-19 morbidity and mortality

Prevalence of SARS-CoV-2 with D614G mutation in a second wave infection in Houston

Molecular analysis of COVID-19's second wave shows mutant viruses linked to rapid spread

Study finds spectrum of genes responsible for inherited hearing loss in Israeli Jewish families

Study shows key genetic differences in ADHD between African American and Caucasian children

Study reveals how people with retinal degenerative disease can maintain night vision

NAU researcher awarded $3.75 million NCI grant to build cancer research software

New $6.2 million study seeks to define molecular linkages between aging and Parkinson's

Industry focus eBook: Genomics (4th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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