Preclinical News and Research

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Study finds higher response to anti-PD1 immunotherapy in older melanoma patients

With each decade of life, the likelihood of progression of melanoma after treatment with anti-PD1 immunotherapy decreased by 13 percent.

13 Jun 2018

MILabs launches new E-Class line of tomographic imaging products

Continuing its customer-centric approach, and fulfilling its commitment to providing preclinical imaging systems of unmatched price/performance, MILabs has introduced its E-Class of tomographic imaging products.

13 Jun 2018

InDevR releases first reagent kit for assessing neuraminidase in influenza vaccines

InDevR Inc. announced product release of the first ever commercial reagent kit designed explicitly for assessment of neuraminidase in influenza vaccines.

12 Jun 2018

Researchers develop 'surgery in a pill' to reverse type 2 diabetes

Over the last decade, bariatric surgeons have made strides in performing weight loss surgery that not only reverses obesity but can also reverse type 2 diabetes in patients with both conditions.

11 Jun 2018

Translate Bio collaborates with Sanofi to develop mRNA vaccines for infectious diseases

Translate Bio, a clinical-stage messenger RNA therapeutics company developing a new class of potentially transformative medicines to treat diseases caused by protein or gene dysfunction, announced today a multi-year research and development collaboration and exclusive licensing agreement with Sanofi Pasteur, the vaccines global business unit of Sanofi, to develop mRNA vaccines for up to five undisclosed infectious disease pathogens.

11 Jun 2018

International experts agree on need for human-relevant research to improve drug discovery

The average pre-approval cost of research and development for a successful drug is estimated to be US$2.6 billion and the number of new drugs approved per billion US dollars spent has halved roughly every 9 years since 1950.

8 Jun 2018

Researchers discover new therapy combination that may help treat ovarian cancer

Researchers at The University of Kansas Cancer Center have discovered a therapy combination that may be helpful in the treatment of certain types of ovarian cancer.

8 Jun 2018

New nuclear medicine method appears to effectively detect neuroendocrine tumors

Researchers have shown that a new nuclear medicine procedure could safely and more effectively detect cancerous gastrointestinal and pancreatic neuroendocrine tumors than current methods.

7 Jun 2018

MR Solutions offers new continuous PET detectors for better imaging

Traditionally PET imaging has been offered with one, two, three or even four rings of detectors with gaps between the rings. MR Solutions, the independent world leader in preclinical imaging, is now offering continuous PET detection thus avoiding any artifacts caused by the gaps between the rings.

From MR Solutions 4 Jun 2018

MILabs' new VECTor5PET/SPECT/OI/CT system installed at TUM campus in Garching

A MILabs VECTor5PET/SPECT/OI/CT system has been installed at the Chair of Pharmaceutical Radiochemistry on the TUM Campus in Garching. Under the direction of Prof. Hans-Jurgen Wester, this institute has established a broad and internationally renowned radiopharmaceutical research program, consisting of fundamental tracer development, innovative radiolabeling strategies, and the preclinical and clinical assessment of new tracers.

31 May 2018

FDA-approved drug for lymphoma and leukemia may help treat common type of brain tumor

New Cleveland Clinic research shows for the first time that ibrutinib, an FDA-approved drug for lymphoma and leukemia, may also help treat the most common – and deadliest – type of brain tumor.

30 May 2018

Early-life seizures prematurely switch on key brain synapses related to autism

Early-life seizures prematurely switch on key synapses in the brain that may contribute to further neurodevelopmental delay in children with autism and other intellectual disabilities, suggests a new study from researchers at Penn Medicine published online in Cell Reports.

29 May 2018

Columbia researchers develop new non-invasive approach to permanently correct vision

Nearsightedness, or myopia, is an increasing problem around the world. There are now twice as many people in the US and Europe with this condition as there were 50 years ago. In East Asia, 70 to 90 percent of teenagers and young adults are nearsighted.

29 May 2018

New non-invasive approach could permanently correct vision

Nearsightedness, or myopia, is an increasing problem around the world. There are now twice as many people in the US and Europe with this condition as there were 50 years ago.

29 May 2018

Antimicrobial peptides are promising alternative for combatting antimicrobial resistance

Overuse of antibiotics has led to the spread of multi-resistant bacteria that do not respond to conventional treatments.

29 May 2018

Snail's eye inspires new type of RIOCATH urinary catheter

The Czech company Riocath Global developed and patented in collaboration with the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences a world-wide unique technology applicable to tubular medical devices. One of the first clinically significant applications is a new form of urinary catheter.

25 May 2018

Scientists create small, self-contained spaces inside mammalian cells

How to install new capabilities in cells without interfering with their metabolic processes? A team from the Technical University of Munich and the Helmholtz Zentrum München have altered mammalian cells in such a way that they formed artificial compartments in which sequestered reactions could take place, allowing the detection of cells deep in the tissue and also their manipulation with magnetic fields.

23 May 2018

Study: Lifetime risks of developing Alzheimer's dementia vary by age, gender

Lifetime risks of developing Alzheimer's disease dementia vary considerably by age, gender and whether any signs or symptoms of dementia are present, according to a new study published online by Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

22 May 2018

New tool predicts the lifetime risk of Alzheimer’s

A new study has shown that the risk of Alzheimer’s disease significantly varies depending on age, gender and the presence of any signs or symptoms of dementia.

22 May 2018

Study: Most people with preclinical signs of Alzheimer's disease may not develop dementia

During the past decade, researchers have identified new ways to detect the earliest biological signs of Alzheimer's disease.

22 May 2018

Preclinical News and Research

Study finds higher response to anti-PD1 immunotherapy in older melanoma patients

MILabs launches new E-Class line of tomographic imaging products

InDevR releases first reagent kit for assessing neuraminidase in influenza vaccines

Researchers develop 'surgery in a pill' to reverse type 2 diabetes

Translate Bio collaborates with Sanofi to develop mRNA vaccines for infectious diseases

International experts agree on need for human-relevant research to improve drug discovery

Researchers discover new therapy combination that may help treat ovarian cancer

New nuclear medicine method appears to effectively detect neuroendocrine tumors

MR Solutions offers new continuous PET detectors for better imaging

MILabs' new VECTor5PET/SPECT/OI/CT system installed at TUM campus in Garching

FDA-approved drug for lymphoma and leukemia may help treat common type of brain tumor

Early-life seizures prematurely switch on key brain synapses related to autism

Columbia researchers develop new non-invasive approach to permanently correct vision

New non-invasive approach could permanently correct vision

Antimicrobial peptides are promising alternative for combatting antimicrobial resistance

Snail's eye inspires new type of RIOCATH urinary catheter

Scientists create small, self-contained spaces inside mammalian cells

Study: Lifetime risks of developing Alzheimer's dementia vary by age, gender

New tool predicts the lifetime risk of Alzheimer’s

Study: Most people with preclinical signs of Alzheimer's disease may not develop dementia

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