Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

EPFL researchers uncover how the circadian clock regulates 3D chromatin structure

EPFL biologists and geneticists have uncovered how the circadian clock orchestrates the 24-hour cycle of gene expression by regulating the structure of chromatin, the tightly wound DNA-protein complex of the cell. The work is published in Genes & Development.

28 Mar 2018

FDA-approved inhibitors could be repurposed to target ARID1A-mutant ovarian cancers

Wistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for the treatment of diseases such as leukemia, as a new therapeutic option for ovarian cancer with mutations in the ARID1A gene.

27 Mar 2018

Researchers probe RNA epigenetics and chromatin structures to predict drug resistance in leukemia

Drug resistance is a major obstacle to effective treatment for patients with cancer and leukemia. Epigenetic modifying drugs have been proven effective for some patients with hematologic malignancies, such as myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML).

23 Mar 2018

Maternal obesity and androgen excess induce sex-specific anxiety in offspring, study suggests

Maternal obesity and androgen excess induce sex-specific anxiety in the offspring, according to a study on mice by researchers at Karolinska Institutet in Sweden published in The FASEB Journal.

22 Mar 2018

Research provides better understanding of how cancerous cells behave in low oxygen

An international team of researchers found how cancer cells respond to DNA damage signaling when in low oxygen, or hypoxia.

21 Mar 2018

Researchers uncover specific gene region in hypertension

Genes encode proteins and proteins dictate cell function. Therefore, the thousands of genes expressed in a cell determine what that cell can do.

20 Mar 2018

Study shows benefits of hair loss drug in improving cognitive function and vascular health

Minoxidil, a popular drug used on the scalp to treat hair loss, might improve blood flow to the brain, lower blood pressure and increase elasticity in the blood vessels if taken in an oral form, according to a new study in mice.

20 Mar 2018

Researchers develop technology to program DNA for delivering cancer drugs

DNA has an important job – it tells your cells which proteins to make. Now, a research team at the University of Delaware has developed technology to program strands of DNA into switches that turn proteins on and off.

19 Mar 2018

Changes in the intestines may be responsible for reversal of diabetes after bariatric surgery

A new study helps explain changes in the intestines that may be responsible for the reversal of diabetes in people who undergo a type of bariatric surgery known as Roux-en-Y gastric bypass surgery.

19 Mar 2018

Consumption of low-calorie sweeteners could promote metabolic syndrome, increase diabetes risk

Consumption of low-calorie sweeteners could promote metabolic syndrome and predispose people to prediabetes and diabetes, particularly in individuals with obesity, a new study on human fat-derived stem cells and fat samples suggests.

19 Mar 2018

Researchers uncover four microRNAs as potential biomarkers for atrial fibrillation

Atrial fibrillation (AF) is a heart condition that causes an irregular, and often rapid, heart rate. It increases the risk of developing strokes, heart failure, and even dementia. Although it can be associated with aging, high blood pressure, diabetes, heart valve problems, etc, about one-third of patients with AF have no symptoms until they suffer a stroke.

16 Mar 2018

Latest Atmospheric Control Unit now available for BMG LABTECH’s budget-friendly product line

Cell-based assays have become an important application in the life science sector, from basic to top-level research. They are widely used in biotech companies and academic research institutions to monitor cell health in real-time.

From BMG LABTECH GmbH 16 Mar 2018

Study highlights divergent molecular mechanisms contributing to depression in men and women

Men and women with major depressive disorder have opposite changes in the expression of the same genes, according to a new postmortem brain study by researchers at the University of Pittsburgh and Centre for Addiction and Mental Health, Toronto, Canada.

14 Mar 2018

Study identifies two new biomarkers for common form of childhood cancer

Two new biomarkers for a type of cancer in children called neuroblastoma have been identified in a study published in the journal Cancer Cell. The findings are expected to have immediate significance for disease prognosis, and eventually also for treatment.

13 Mar 2018

International research consortium identifies 22 new genetic risk factors for stroke

An international research consortium studying 520,000 individuals from around the world has identified 22 new genetic risk factors for stroke, thus tripling the number of gene regions known to affect stroke risk.

13 Mar 2018

Study identifies gene that influences risk of obesity in adulthood

The importance of good nutrition in the early development of children has been recognized for many decades. Nutritional experiences in early life can have profound and long-lasting effects on body weight in later life.

13 Mar 2018

Researchers show role for predictive biomarker in neonatal chronic lung disease pathogenesis

Extremely low birth-weight babies are at risk for a chronic lung disease called bronchopulmonary dysplasia, or BPD.

9 Mar 2018

Study reveals key function of ALS-linked protein

The protein FUS, whose mutation or disruption causes many cases of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), works as a central component of one of the most important regulatory systems in cells, according to a new study in Molecular Cell from scientists at Johns Hopkins Bloomberg School of Public Health.

8 Mar 2018

Scientists discover 36 previously unknown genes implicated in heart failure

One in four deaths in the United States each year are due to heart disease, according to the Centers for Disease Control and Prevention. It's the leading killer of both men and women, but the disease's genetic complexity makes it difficult to treat.

8 Mar 2018

Researchers identify new mechanism to disrupt HIV latency

HIV, the virus that causes AIDS, has a secret life. Though anti-retroviral therapy can reduce its numbers, the virus can hide and avoid both treatments and the body's immune response.

8 Mar 2018

Gene Expression News and Research

Further Reading

EPFL researchers uncover how the circadian clock regulates 3D chromatin structure

FDA-approved inhibitors could be repurposed to target ARID1A-mutant ovarian cancers

Researchers probe RNA epigenetics and chromatin structures to predict drug resistance in leukemia

Maternal obesity and androgen excess induce sex-specific anxiety in offspring, study suggests

Research provides better understanding of how cancerous cells behave in low oxygen

Researchers uncover specific gene region in hypertension

Study shows benefits of hair loss drug in improving cognitive function and vascular health

Researchers develop technology to program DNA for delivering cancer drugs

Changes in the intestines may be responsible for reversal of diabetes after bariatric surgery

Consumption of low-calorie sweeteners could promote metabolic syndrome, increase diabetes risk

Researchers uncover four microRNAs as potential biomarkers for atrial fibrillation

Latest Atmospheric Control Unit now available for BMG LABTECH’s budget-friendly product line

Study highlights divergent molecular mechanisms contributing to depression in men and women

Study identifies two new biomarkers for common form of childhood cancer

International research consortium identifies 22 new genetic risk factors for stroke

Study identifies gene that influences risk of obesity in adulthood

Researchers show role for predictive biomarker in neonatal chronic lung disease pathogenesis

Study reveals key function of ALS-linked protein

Scientists discover 36 previously unknown genes implicated in heart failure

Researchers identify new mechanism to disrupt HIV latency

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