Kidney News and Research

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SARS-CoV-2 viral load predicts risk of death

As the coronavirus pandemic evolved, there have been many developments in testing for the SARS-CoV-2 viral load in patients. Now, a team of researchers at the Icahn School of Medicine at Mount Sinai, New York, has found that the SARS-CoV-2 viral load can predict mortality in patients with coronavirus disease (COVID-19).

13 Aug 2020

FDA approves new treatment option for patients with rare Duchenne muscular dystrophy mutation

Today, the U.S. Food and Drug Administration granted accelerated approval to Viltepso (viltolarsen) injection for the treatment of Duchenne muscular dystrophy (DMD) in patients who have a confirmed mutation of the DMD gene that is amenable to exon 53 skipping.

12 Aug 2020

Physicians report misuse of thyroid tests for unsupported reasons

Up to one-third of physicians reported sending patients for a thyroid ultrasound for reasons not supported by clinical care guidelines, a new study led by University of Michigan Rogel Cancer Center researchers finds.

12 Aug 2020

Study: High blood sugar may trigger worse outcomes in COVID-19 patients

As COVID-19 continues to rage across the U.S., researchers are digging deeper into how the virus wreaks havoc on the body, especially for those with a pre-existing chronic illness.

12 Aug 2020

Research looks at convalescent plasma use in COVID-19 mouse model

A new study by researchers at the University of Iowa and published on the preprint server bioRxiv in August 2020 reports the utility of a mouse model that recapitulates several aspects of human COVID-19 and can reflect the antiviral efficacy of new drugs as well.

12 Aug 2020

Smoking and vaping significantly increase risk of COVID-19 in teens and young adults

Now, a new study published in the Journal of Adolescent Health shows that teens and young adults may have a heightened risk of COVID-19 if they vape or smoke cigarettes. Cigarette smokers are seven times more likely to be infected with SARS-CoV-2. Meanwhile, people who vape are five times more likely to be diagnosed with the viral infection.

11 Aug 2020

Scientist explains why COVID-19 targets only some organs while others are spared

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses the enzyme angiotensin-converting enzyme 2 (ACE2) to enter and infect human cells. It causes COVID-19 and can lead to a multitude of complications, including multi-organ impairment, partially due to the abundant expression of ACE2 in all human tissues.

11 Aug 2020

Pupil size predicts death and hospital readmission in patients with heart failure

Pupil size predicts death and hospital readmission in patients with heart failure, according to research published today in ESC Heart Failure, a journal of the European Society of Cardiology (ESC).1

11 Aug 2020

Researchers reveal molecular workings of a key system in learning and memory formation

One of the new realities in biomedical research is that it's increasingly difficult to use a general approach to score advances. Now, investigations into disease mechanisms, for example, are often conducted at the molecular level by specialists who dedicate years to interrogating a single protein or signaling pathway.

10 Aug 2020

Real-life discussions may help counter anti-vaccination influences from social media

The flu vaccine is considered one of the great achievements in public health, and each year it prevents millions of people from getting sick and thousands of deaths.

10 Aug 2020

Proteinuria reduction slows kidney decline in patients with focal segmental glomerulosclerosis

Reducing the amount of protein in the urine of patients with focal segmental glomerulosclerosis (FSGS), a rare disease in which scar tissue forms on the parts of the kidneys that filter waste from the blood, can significantly slow declines in kidney function and extend time before patients' kidneys fail, a new analysis by a Children's National Hospital researcher and her colleagues shows.

10 Aug 2020

Non-fasting blood test can help accurately identify youth at risk for diabetes and related risks

A simple blood test that does not require overnight fasting has been found to be an accurate screening tool for identifying youth at risk for type 2 diabetes and heart disease risk later in life, according to a study from researchers at the Johns Hopkins Bloomberg School of Public Health.

10 Aug 2020

Study shows link between high blood lead levels and aberrant methylation of DNA

Scientists have unveiled a correlation between high blood lead levels in children and methylation of genes involved in haem synthesis and carcinogenesis, indicating a previously unknown mechanism for lead poisoning.

7 Aug 2020

USF Health researchers develop new reporter mouse strain for identifying P2X2-expressing cells

Despite frequent news announcing "medical breakthroughs," advancements in biomedical and clinical science typically happen incrementally.

7 Aug 2020

Immunothrombotic dysregulation is key marker of disease severity in COVID-19

In severe cases of COVID-19, the infection can lead to obstruction of the blood vessels in the lung, heart and kidneys. Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have now shown that activated immune cells and blood platelets play a major role in these pathologies.

7 Aug 2020

Large-scale analysis of Alport syndrome reveals the effectiveness of existing treatments

A large-scale analysis of the clinical characteristics of Alport syndrome in Japanese patients has revealed that the effectiveness of existing treatment with ACE inhibitors and/or angiotensin receptor blockers (RAS inhibitors) varies depending on the type of mutation in the syndrome's causal gene (COL4A5).

7 Aug 2020

Researchers use patient-specific tumor organoid to optimize chemotherapy for appendix, colon tumors

A patient-specific tumor organoid model is being used to identify the most effective chemotherapy protocol to treat appendix and colon tumors, a personalized medicine approach that is showing promise.

7 Aug 2020

Marshall University researcher awarded NIH grant to study uremic cardiomyopathy

Komal Sodhi, M.D., an associate professor of surgery and biomedical sciences at the Marshall University Joan C. Edwards School of Medicine, has been awarded a $444,000 grant from the National Institutes of Health to further her research on cardiomyopathy associated with chronic renal failure, or uremic cardiomyopathy.

6 Aug 2020

3D organoid model helps better understand how tumor grows in natural microenvironment

Scientists at the Wake Forest Institute for Regenerative Medicine (WFIRM) have biofabricated human colorectal cancer miniature organs, called organoids, to better understand how a tumor grows in its natural microenvironment and its response to therapies.

5 Aug 2020

Study provides comprehensive update on ACE2 enzyme with key role in SARS-CoV-2 infection

Researchers at Uppsala University have described the presence, throughout the human body, of the enzyme ACE2.

5 Aug 2020

Kidney News and Research

SARS-CoV-2 viral load predicts risk of death

FDA approves new treatment option for patients with rare Duchenne muscular dystrophy mutation

Physicians report misuse of thyroid tests for unsupported reasons

Study: High blood sugar may trigger worse outcomes in COVID-19 patients

Research looks at convalescent plasma use in COVID-19 mouse model

Smoking and vaping significantly increase risk of COVID-19 in teens and young adults

Scientist explains why COVID-19 targets only some organs while others are spared

Pupil size predicts death and hospital readmission in patients with heart failure

Researchers reveal molecular workings of a key system in learning and memory formation

Real-life discussions may help counter anti-vaccination influences from social media

Proteinuria reduction slows kidney decline in patients with focal segmental glomerulosclerosis

Non-fasting blood test can help accurately identify youth at risk for diabetes and related risks

Study shows link between high blood lead levels and aberrant methylation of DNA

USF Health researchers develop new reporter mouse strain for identifying P2X2-expressing cells

Immunothrombotic dysregulation is key marker of disease severity in COVID-19

Large-scale analysis of Alport syndrome reveals the effectiveness of existing treatments

Researchers use patient-specific tumor organoid to optimize chemotherapy for appendix, colon tumors

Marshall University researcher awarded NIH grant to study uremic cardiomyopathy

3D organoid model helps better understand how tumor grows in natural microenvironment

Study provides comprehensive update on ACE2 enzyme with key role in SARS-CoV-2 infection

Free guide - Everything about renal proximal tubule cells eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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