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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Constructing SARS-CoV-2 virus-like particles in tobacco plants for vaccine development

In a study published in the latest issue of the Scientific Reports, a team of researchers constructed virus-like particles (VLPs) composed of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M), envelope (E), and nucleocapsid (N) proteins in tobacco plant using Agrobacterium-mediated delivery.

24 Jan 2022

Lower risk of vaccine-breakthrough infections for mRNA-1273 recipients

Recently, a team of researchers examined breakthrough infections, hospitalizations, and mortality rates in double-dose messenger RNA (mRNA) vaccine recipients in a research letter published in the Journal of American Medical Association (JAMA).

24 Jan 2022

Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

In a new study, researchers evaluated the single-cell transcriptomes from bronchiolar lavage in three adult cohorts comprising of obese and non-obese SARS-CoV-2 patients.

24 Jan 2022

Short- and long-term systemic responses in the golden hamster following SARS-CoV-2 or influenza A virus infection

A group of researchers used the golden hamster as a model system to better understand the long-term impacts of SARS-CoV-2 infection.

24 Jan 2022

Exploring loss of Y chromosome in white blood cells as a risk-factor of life-threatening COVID-19 in men

Researchers published a study exploring the possibilities of predisposing men for a life-threatening disease course of COVID-19.

24 Jan 2022

Characterization of unique pathogenesis of SARS-CoV-2 Delta variant in mouse model

Researchers have investigated the pathology and inflammatory response to the Delta variant in mice.

24 Jan 2022

Human endogenous retrovirus type W envelope protein found to be a biomarker of COVID-19 severity

A new study revealed that the expression of HERV-W envelope protein (ENV) in lymphoid cells from COVID-19 patients correlated with disease outcome making them biomarkers of lymphocyte exhaustion.

24 Jan 2022

Researchers find ELF5 gene a leading candidate behind severe COVID-19

Are there any risk factors that predispose patients to severe COVID-19 outcomes? A recent study published in the medRxiv* preprint server sheds light on this popular question. Using a combination of population genetics to single-cell RNA sequencing, European researchers identified the respiratory epithelial cell-specific ELF5 gene as a potential mediator for severe COVID-19 cases.

24 Jan 2022

Nirmatrelvir, Molnupiravir, and Remdesivir hold-up against SARS-CoV-2 Omicron variant in vitro

In a recent study posted to the bioRxiv* preprint server, researchers test three severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antivirals authorized for emergency use by the United States Food and Drug Administration (FDA) for their in vitro potency against several SARS-CoV-2 variants, including the currently dominant Omicron train.

23 Jan 2022

Novel SARS-CoV-2 mutations reported in chronic HIV patients

A new study describes the emergence of new SARS-CoV-2 variants in three immunocompromised patients.

23 Jan 2022

Paxlovid provides a glimpse into the future against SARS-CoV-2

A recent study reveals that nirmatrelvir is potent and effective against the SARS-CoV-2 Omicron variant.

23 Jan 2022

Rapid, highly accurate drug detection vital to reducing the adverse impacts of addiction

Rapid, accessible and highly accurate detection of addictive substances such as opiates and cocaine is vital to reducing the adverse personal and societal impacts of addiction, something current drug detection systems can take too long to provide.

22 Jan 2022

Echinacea as a potential force against coronavirus infections

A new review identified clinical studies evaluating coronavirus infections in the context of Echinacea administration and assessed preventive and therapy advantages against COVID-19.

21 Jan 2022

Alphacoronaviruses found to be common in bats in the upper Midwestern United States

In a new study, researchers used a pan-coronavirus PCR to screen bats submitted for rabies testing owing to human exposure in order to find potentially novel bat CoVs that may represent a concern to people.

21 Jan 2022

Researchers develop new biological parts to shape the flow of cellular processes along DNA

Scientists at the University of Bristol have developed new biological parts that are able to shape the flow of cellular processes along DNA.

21 Jan 2022

New COVID-19 vaccine promises vaccine equity because it has no patents

Corbevax, a new vaccine against COVID-19, may have better success as a candidate for vaccine equity because it carries no patents, relies on long-established recombinant technology for manufacture and has the support of the US and Indian governments, its makers and health experts say.

21 Jan 2022

RNA News and Research

Further Reading

Constructing SARS-CoV-2 virus-like particles in tobacco plants for vaccine development

Lower risk of vaccine-breakthrough infections for mRNA-1273 recipients

Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

Short- and long-term systemic responses in the golden hamster following SARS-CoV-2 or influenza A virus infection

Exploring loss of Y chromosome in white blood cells as a risk-factor of life-threatening COVID-19 in men

Characterization of unique pathogenesis of SARS-CoV-2 Delta variant in mouse model

Human endogenous retrovirus type W envelope protein found to be a biomarker of COVID-19 severity

Researchers find ELF5 gene a leading candidate behind severe COVID-19

Nirmatrelvir, Molnupiravir, and Remdesivir hold-up against SARS-CoV-2 Omicron variant in vitro

Novel SARS-CoV-2 mutations reported in chronic HIV patients

Paxlovid provides a glimpse into the future against SARS-CoV-2

Rapid, highly accurate drug detection vital to reducing the adverse impacts of addiction

Echinacea as a potential force against coronavirus infections

Alphacoronaviruses found to be common in bats in the upper Midwestern United States

Researchers develop new biological parts to shape the flow of cellular processes along DNA

New COVID-19 vaccine promises vaccine equity because it has no patents

SARS-CoV-2 prevalence in bivalve mollusks from harvesting areas in Southern Italy

New production method developed to freeze-dry COVID-19 vaccines

Scientists explore the possibility of Omicron ending the COVID-19 pandemic

Prospective of graphene and graphene-based derivatives to combat SARS-CoV-2 infection

New Approach Methodologies, the 3Rs and Multimodal Imaging in Preclinical Research - eBook eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

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Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo