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Microbial diversity can improve treatment for cancer patients

Physicians at City of Hope, working in collaboration with scientists at Translational Genomics Research Institute (TGen), have found that greater gut microbial diversity in patients with metastatic kidney cancer is associated with better treatment outcomes on Food and Drug Administration-approved immunotherapy regimens.

19 Aug 2020

Study shows how bats survive the Ebola virus

A new study by researchers from The University of Texas Medical Branch at Galveston uncovered new information on why the Ebola virus can live within bats without causing them harm, while the same virus wreaks deadly havoc to people. This study is now available in Cell Reports.

19 Aug 2020

Democratic convention, night 1: Hitting Trump team on pandemic preparedness

On the first night of the Democrats’ 2020 national convention, one thing was clear. This time would be different. No crowds, buttons, placards or party swag. The coronavirus pandemic was an ever-present theme.

18 Aug 2020

Study shows why young, female patients have low response rates to cancer immunotherapy

Cancer immunotherapy -- empowering a patient's own immune system to clear away tumors on its own -- holds great promise for some patients. But for other patients, immunotherapy just doesn't work.

18 Aug 2020

Genome analysis helps detect 568 genes that drive cancer

Analysis of the genomes of 28,000 tumors from 66 types of cancer has led to the identification of 568 cancer driver genes

17 Aug 2020

Women investigators can attract more women patients in heart failure clinical trials

While about a quarter of physicians and researchers working in advanced heart failure (HF) and transplant cardiology are women, representation of women leading HF research remains limited, according to new research led by Penn Medicine.

17 Aug 2020

Genomic analysis finds link between antibiotic resistance and heavy metal contamination

Antibiotic resistance is an increasing health problem, but new research suggests it is not only caused by the overuse of antibiotics. It's also caused by pollution.

13 Aug 2020

Scientists identify genetic link to predict treatment response in patients with aggressive blood cancer

A Singapore team led by clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) discovered a genetic link to better predict treatment response for relapsed/refractory patients with natural- killer T-cell lymphoma (NKTCL), a highly aggressive form of blood cancer.

13 Aug 2020

Study of 300 COVID-19 patients shows efficacy of convalescent plasma therapy

A preliminary analysis of an ongoing study of more than 300 COVID-19 patients treated with convalescent plasma therapy at Houston Methodist suggests the treatment is safe and effective.

12 Aug 2020

SPT enzyme can be used as metabolically responsive “switch” to slow tumor growth

The enzyme serine palmitoyl-transferase can be used as a metabolically responsive "switch" that decreases tumor growth, according to a new study by a team of San Diego scientists, who published their findings Aug. 12 in the journal Nature.

12 Aug 2020

Researchers develop novel approach for utilizing 4D-printing of arrays to accelerate drug testing

Investigators at Rutgers Cancer Institute of New Jersey have developed a novel approach for utilizing 4-dimensional (4D) printing of arrays that transform from cell-culture inserts into histological cassettes that hold patient tissue samples for rapid programmable drug testing.

12 Aug 2020

Study focuses on genetic neurological disorders that develop in children over time

A team of researchers at Children's Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) further bridged the gap between genomic information and clinical outcome data by systematically linking genetic information with electronic medical records, focusing on how genetic neurological disorders in children develop over time.

12 Aug 2020

Research looks at convalescent plasma use in COVID-19 mouse model

A new study by researchers at the University of Iowa and published on the preprint server bioRxiv in August 2020 reports the utility of a mouse model that recapitulates several aspects of human COVID-19 and can reflect the antiviral efficacy of new drugs as well.

12 Aug 2020

SARS-CoV-2 a "swarm" of mutant viruses

In this new study, the virus was serially passaged in independent cell types in a controlled environment. The researchers found that the virus rapidly adapts to the changing conditions in culture by selecting for pre-existing species.

12 Aug 2020

Genomic sequencing falls short as a standalone screening tool for newborns

With the rise of genomic sequencing, health technology companies are promising parents they can detect rare metabolic disorders in newborns who, despite a healthy appearance, may need immediate treatment.

10 Aug 2020

Rice engineers use gene editing to facilitate drug discovery based on natural fungus

Rice University scientists have won federal support for their pursuit of novel drugs to treat human disease.

10 Aug 2020

HPV type may impact cervical cancer characteristics and prognosis

An analysis of cervical cancers in Ugandan women has uncovered significant genomic differences between tumors caused by different strains of human papillomavirus (HPV), signifying HPV type may impact cervical cancer characteristics and prognosis.

10 Aug 2020

Quantum cryptographic communications technology can provide safe, secure data transmission in genomic medicine

Toshiba Corporation, Tohoku University Tohoku Medical Megabank Organization and Tohoku University Hospital have demonstrated that quantum cryptographic communications technology can provide genomic medicine with a safe, completely secure data management environment.

10 Aug 2020

Study suggests novel strategy to slow down evolution of antibiotic resistance

The rise of antibiotic resistance in many pathogens has been driven by the spread of a small number of strains, suggesting that some bacteria may be genetically pre-disposed to evolving resistance.

10 Aug 2020

USA the source of most of New Zealand's coronavirus cases

New Zealand, an island country in the southwestern Pacific Ocean, is marked by its early and fierce determination to totally arrest the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the viral illness that is causing the current COVID-19 pandemic.

9 Aug 2020

Genomic News and Research

Microbial diversity can improve treatment for cancer patients

Study shows how bats survive the Ebola virus

Democratic convention, night 1: Hitting Trump team on pandemic preparedness

Study shows why young, female patients have low response rates to cancer immunotherapy

Genome analysis helps detect 568 genes that drive cancer

Women investigators can attract more women patients in heart failure clinical trials

Genomic analysis finds link between antibiotic resistance and heavy metal contamination

Scientists identify genetic link to predict treatment response in patients with aggressive blood cancer

Study of 300 COVID-19 patients shows efficacy of convalescent plasma therapy

SPT enzyme can be used as metabolically responsive “switch” to slow tumor growth

Researchers develop novel approach for utilizing 4D-printing of arrays to accelerate drug testing

Study focuses on genetic neurological disorders that develop in children over time

Research looks at convalescent plasma use in COVID-19 mouse model

SARS-CoV-2 a "swarm" of mutant viruses

Genomic sequencing falls short as a standalone screening tool for newborns

Rice engineers use gene editing to facilitate drug discovery based on natural fungus

HPV type may impact cervical cancer characteristics and prognosis

Quantum cryptographic communications technology can provide safe, secure data transmission in genomic medicine

Study suggests novel strategy to slow down evolution of antibiotic resistance

USA the source of most of New Zealand's coronavirus cases

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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