Compound News and Research

RSS

Driving performance unaffected in regular cannabis users after 48 hours of abstinence

Scientists from the Center for Medicinal Cannabis Research (CMCR) at the University of California San Diego School of Medicine found that, in the largest such study to date, frequent cannabis users did not display impairments in driving performance after at least 48 hours of abstinence.

11 Sep 2025

Citrus flavonoid hesperidin lowers oxidative damage in cell experiments

Researchers tested hesperidin extracted from citrus peels and found it reduced inflammatory cytokines and oxidative stress markers in cultured immune cells. The findings highlight hesperidin’s strong in vitro anti-inflammatory and antioxidant potential, warranting further in vivo research.

11 Sep 2025

Can cannabis use disrupt women’s fertility? New study finds strong evidence

Researchers found that THC, the psychoactive compound in cannabis, alters oocyte gene expression, spindle formation, and chromosome segregation, lowering embryo euploidy rates in IVF. This provides direct human evidence linking cannabis exposure to impaired female fertility outcomes.

10 Sep 2025

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Discover how real-time Raman monitoring enhances API control and quality during hot melt extrusion.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 10 Sep 2025

IFITM3 found to be critical regulator of immunotherapy sensitivity in small cell lung cancer

New research presented identifies interferon-induced transmembrane protein 3 (IFITM3) as a critical regulator of immunotherapy sensitivity in small cell lung cancer (SCLC), offering a promising new avenue for overcoming resistance to PD-1/PD-L1 checkpoint blockade.

9 Sep 2025

Berberine improves cognitive function in diabetic encephalopathy mice

A recent study published in Engineering has shed new light on the potential therapeutic effects of berberine (BBR), a natural compound derived from traditional Chinese medicine, in treating diabetic encephalopathy (DE).

9 Sep 2025

How breast milk changes from day to night and why timing matters

Breast milk's hormonal and microbial variations throughout the day may affect infant development, emphasizing the need for synchronized feeding practices.

8 Sep 2025

New 3D eye model reveals causes of steroid-related glaucoma

The eye, like most organs, has an intricate plumbing system. Pressure builds when drainage is impaired, and this condition – glaucoma – can cause irreversible vision loss.

4 Sep 2025

Roasted Arabica coffee hides powerful antidiabetic molecules

Three novel coffee diterpene esters, caffaldehydes A, B, and C, were discovered in Arabica beans, showcasing significant alpha-glucosidase inhibitory activity.

3 Sep 2025

How raspberry leaf tea reduces insulin surges from table sugar

Trial shows that raspberry leaf tea blunts sucrose-induced glucose and insulin surges, offering a natural strategy for moderating blood sugar without the side effects of pharmaceutical enzyme inhibitors.

2 Sep 2025

New drug dismantles cancer cell powerhouse to halt tumor growth

Researchers at MUSC Hollings Cancer Center have discovered a potentially powerful weapon in the fight against head and neck cancers.

2 Sep 2025

Plant-derived carotenoid found to boost immune response against cancer

In a new study, researchers from the University of Chicago discovered that zeaxanthin, a plant-derived carotenoid best known for protecting vision, may also act as an immune-boosting compound by strengthening the cancer-fighting activity of immune cells.

2 Sep 2025

Compounds show significant inhibitory effects on α-glucosidase

Three of the compounds demonstrated significant inhibitory effects on α-glucosidase, a key enzyme in carbohydrate digestion. The findings could pave the way for new functional food ingredients targeting type 2 diabetes.

2 Sep 2025

Research reveals molecular details of ME/CFS and long COVID

Patients with chronic fatigue syndrome/myalgic encephalomyelitis (ME/CFS) have heightened innate immune responses to bacteria, viruses, and fungi. While these responses are essential to fight infection, they can cause damage when unchecked.

1 Sep 2025

Disrupting protein quality control slows tumor growth in pediatric rhabdomyosarcoma

A new research paper was published in Volume 16 of Oncotarget on August 29, 2025, titled "In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma."

29 Aug 2025

Metals and sulfate particles drive asthma hospitalizations linked to air pollution

Metals, particularly nickel and vanadium, and sulfate particles are the components of fine particulate air pollution (PM2.5) that most strongly contribute to the association between long-term exposure to air pollution and hospitalization among asthma sufferers, according to a new study led by Harvard T.H. Chan School of Public Health.

29 Aug 2025

New reaction approach expands possibilities for drug discovery building blocks

A new approach to an established reaction boosts the ability to synthesize vinylic ethers - key building blocks for many molecules important to human health.

28 Aug 2025

First clinical trial in cats tests targeted therapy for deadly head and neck cancer

Researchers have reported results from the first-ever clinical trial of a new class of targeted therapy in pet cats with head and neck squamous cell carcinoma (HNSCC)-a cancer which is notoriously deadly and difficult to treat.

28 Aug 2025

Stanford scientists make mouse skin transparent to study brain development

During childhood and adolescence, our brain goes through a lot of changes. But studying those changes in juvenile mice is challenging because scientists don't have a way to repeatedly image the same animal's neural pathways as they grow.

28 Aug 2025

New oral antiretroviral shows potential as long-acting HIV pre-exposure prophylaxis

A new HIV antiretroviral shows promise as a long-acting, oral prophylactic agent, according to a new study by Izzat Raheem, Tracy Diamond and colleagues from Merck & Co., Inc., Rahway, NJ, USA, published August 26th in the open-access journal PLOS Biology.

26 Aug 2025