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Open source tool automates data reanalysis to detect rare diseases

A newly developed open-source tool designed for rigorous reanalysis of genomic data is highly effective at detecting new rare disease diagnoses.

24 Jun 2026

Comprehensive gut microbiome analysis reveals robust colorectal cancer signature

Researchers have long suspected that the gut microbiome – the community of bacteria and other microorganisms living in the intestine – is closely linked to colorectal cancer.

24 Jun 2026

Common genetic difference may increase the risk of severe COVID-19 and lung fibrosis

A genetic difference carried by nearly one in three people may increase the risk of severe COVID-19 and lung fibrosis by disrupting the function of a previously unknown protein, according to a new study.

24 Jun 2026

Study reveals early immune clues to predict active tuberculosis risk

An early view of the immune response to bacteria in the lungs provides clues as to why some people keep TB in check, while others develop disease, suggesting new ways to intervene earlier and stop TB.

24 Jun 2026

Hidden protein linked to severe COVID-19 and lung disease risk

24 Jun 2026

Melatonin improves skin flap survival by reducing ferroptosis

Random-pattern skin flaps are widely used to repair defects caused by trauma, burns, tumor removal, and other injuries because they can be designed without depending on a single named blood vessel.

23 Jun 2026

Gene therapy shows promise against deadly childhood liver disease

A new gene therapy has been used to successfully treat a deadly childhood liver disease using mice that model this disease by researchers at UCL and Great Ormond Street Hospital.

23 Jun 2026

Scientists uncover new molecular mechanism driving gastrointestinal stromal tumors

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive tract, with KIT mutations driving approximately 75% to 80% of cases.

23 Jun 2026

Parental genes rather than pregnancy weight influence childhood body mass index

The link between parents' body mass index (BMI) and their children's BMI in childhood is driven largely by genetic inheritance, rather than by any direct biological effects of parental weight during pregnancy, a new study suggests.

23 Jun 2026

Cytoskeletal proteins in the cell nucleus influence brain development

The cytoskeleton gives cells their shape and helps them move. Researchers at Helmholtz Munich and the Ludwig Maximilian University now show that, in neural stem cells, proteins of the cytoskeleton are also found in the cell nucleus, where they can influence developmental programs.

23 Jun 2026

New project aims to systematically map billion cellular interactions

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23 Jun 2026

Psychological traits may uncover why Alzheimer’s biology differs between patients

In 822 deceased older adults from ROS and MAP, researchers linked stable psychological traits to multi-omic molecular subtypes of Alzheimer’s dementia using postmortem brain tissue from the dorsolateral prefrontal cortex. Neuroticism and loneliness were associated with molecular progression, while purpose in life showed subtype-specific inverse associations, suggesting psychological traits may align with Alzheimer’s biology beyond conventional neuropathology.

22 Jun 2026

Using the mathematics of quantum mechanics to improve neuroblastoma outcomes

For a child diagnosed with neuroblastoma-the most common infant cancer, occurring when early nerve cells grow out of control-the path to treatment isn't simple.

22 Jun 2026

Study links genes and sleep habits to Alzheimer's risk

New research from Edith Cowan University (ECU) has discovered an important link between our genes and sleep habits, suggesting they work together to influence early brain and cognitive changes associated with Alzheimer's Disease, long before symptoms appear.

22 Jun 2026

Mount Sinai study connects social determinants of health to disease risks

A new study from the Icahn School of Medicine at Mount Sinai shows that social determinants of health-including environmental conditions, health behaviors, access to resources, and social well-being-can play an equally important or even greater role than genetics in predicting a person's risk of developing common diseases.

22 Jun 2026

GATA6 loss transforms colorectal cancer cells into metastatic states

Loss of GATA6-a transcription factor that controls which genes are turned on or off-can reprogram colorectal cancer cells into more primitive, adaptable states that can then spread to the liver and establish new tumors, according to Weill Cornell Medicine and Massachusetts Institute of Technology researchers.

22 Jun 2026

Study links neuroimmune dysregulation to complex fibromyalgia symptoms

Fibromyalgia is a complex disorder characterized primarily by chronic widespread pain, fatigue and other physical and cognitive symptoms.

22 Jun 2026

Novel gene network approach reveals new schizophrenia risk genes

Scientists have long known that schizophrenia runs in families, but pinpointing exactly which genes contribute to risk has been like searching for needles in a haystack.

22 Jun 2026

New drug could double survival time in patients with advanced pancreatic cancer

A new medication could double survival time in patients with advanced pancreatic cancer, according to Phase III clinical trial results presented at the American Society of Clinical Oncology (ASCO) 2026 annual meeting and simultaneously published in The New England Journal of Medicine.

22 Jun 2026

Plague emerged earlier than thought and hit hunter-gatherers hard

Ancient DNA from 46 Lake Baikal hunter-gatherers revealed two early plague outbreak phases about 5,500 years ago, with Yersinia pestis detected in 18 individuals. The findings suggest these basal plague strains caused lethal, child-heavy outbreaks long before dense farming societies, cities, or classical flea-borne bubonic plague emerged.

21 Jun 2026