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Study reveals how bacterial collagenase efficiently breaks down collagen

Collagen is an important protein that helps build the tissues of humans and animals. It is very strong because it is made of three protein strands twisted tightly together like a rope. Because of this sturdy structure, ordinary protein-cutting enzymes usually cannot break it down.

3 Apr 2026

Overnight machine perfusion enables safe daytime liver transplants

It is safe for patients to receive a donor liver that has been intentionally preserved overnight using machine perfusion to enable a daytime transplant.

3 Apr 2026

High-dose radiation improves survival in large bile duct tumors

A new study from researchers at The University of Texas MD Anderson Cancer Center demonstrates that a specialized high-dose type of radiation delivery may significantly improve outcomes for patients with large bile duct tumors in the liver, known as intrahepatic cholangiocarcinoma.

2 Apr 2026

Study reveals pearling mechanism behind mitochondrial DNA spacing

Mitochondria are often described as the cell's power plants, because they generate energy. To help them achieve this, mitochondria carry their own small genome called mitochondrial DNA (mtDNA).

2 Apr 2026

Oral molecule prevents kidney stones and restores survival in mice

Scientists at the Buck Institute for Research on Aging have shown that an orally administered small molecule, N-propargylglycine (N-PPG), can completely prevent the formation of calcium oxalate kidney stones, protect against kidney failure, and fully restore normal survival in a mouse model of Primary Hyperoxaluria Type 2 (PH2), a rare and currently untreatable genetic disorder that causes progressive kidney failure in infants and young adults.

2 Apr 2026

Occasional heavy drinking poses major risk to liver health

People may assume that if they drink lightly during the week or month, heavy drinking on the occasional Friday or Saturday may not cause their liver harm.

2 Apr 2026

International researchers set new standards for studying tumor microbiota

Recent research shows that tumors in different organs host microbial communities capable of influencing cancer biology, immune responses, and the effectiveness of therapies, highlighting the need to standardize methods for studying intratumoral microbes.

2 Apr 2026

Gene-edited treatment shows promising outcomes for severe sickle cell disease

New results from a clinical trial show promising outcomes for a gene-edited treatment for severe sickle cell disease, a genetic blood disorder with few curative options.

1 Apr 2026

Pesticide exposure linked to higher cancer risk in new study

A new scientific study, published in Nature Health, reveals a strong link between exposure to agricultural pesticides in the environment and the risk of developing cancer.

1 Apr 2026

Gut microbiome changes improve memory in early cognitive decline

Research shows that modifying the gut microbiome can enhance cognitive performance and mitigate dementia risk, highlighting the gut-brain connection.

1 Apr 2026

Fiber supplement stabilizes blood sugar in gestational diabetes

Dietary fiber supplementation shows potential in managing blood sugar levels and preventing preterm births in pregnancies at risk for gestational diabetes.

1 Apr 2026

Imaging study measures pancreatic fat in children and teens

Higher fat content in the pancreas of children and adolescents with obesity is associated with an increased level of heart and metabolic risk factors, including higher than average body mass index (BMI), elevated diastolic blood pressure, higher levels of abdominal and liver fat, and insulin resistance, according to new research presented at this year's European Congress on Obesity (ECO) in Istanbul, Turkey (12-15 May).

1 Apr 2026

What happens when more of your exercise is vigorous instead of moderate?

In a large UK Biobank analysis, a higher proportion of vigorous physical activity relative to total activity volume was associated with lower risks of eight major chronic diseases and all-cause mortality, even after accounting for overall activity volume. Device-based data suggested that activity intensity generally offered greater preventive potential than total volume alone across most outcomes.

31 Mar 2026

Novel compound clears harmful protein, protects neurons in frontotemporal dementia models

New research from Washington University School of Medicine in St. Louis adds to growing evidence that helping brain cells break down and eliminate their own cellular waste is a promising treatment strategy for a variety of neurodegenerative diseases.

31 Mar 2026

Lung cancer scans can reveal signs of other undiagnosed cancers

When doctors review diagnostic medical scans for lung cancer, they sometimes spot abnormalities unrelated to the lungs.

31 Mar 2026

Gene signature maps cholangiocarcinoma subtypes for precision treatment

Intrahepatic cholangiocarcinoma (iCCA), the second most common primary liver cancer after hepatocellular carcinoma, remains one of the most challenging malignancies to treat due to its highly concealed and heterogeneous nature.

31 Mar 2026

New genetic ‘roadmap’ advances precision therapy for intrahepatic cholangiocarcinoma

The 1,341-gene signature for intrahepatic cholangiocarcinoma offers a framework for precise diagnosis and tailored therapies, addressing tumor heterogeneity.

From BGI Genomics 31 Mar 2026

How gut imbalance may drive obesity, diabetes, and heart disease

A new review argues that gut dysbiosis is closely linked to metabolic dysfunction through intertwined effects on inflammation, oxidative stress, gut barrier integrity, microbial metabolites, and epigenetic regulation. It also highlights microbiome-targeted strategies such as high-fiber diets, probiotics, prebiotics, postbiotics, exercise, and fecal microbiota transplantation as promising ways to support metabolic health.

30 Mar 2026

New initiative aims to improve care for people living with Fontan circulation

The lifesaving surgery used to treat children with single ventricle heart disease, the Fontan procedure, can pose serious health complications throughout life.

30 Mar 2026

Study links atrial fibrillation to poorer brain clearance and cognitive decline

Researchers found that people with atrial fibrillation had lower MRI-based glymphatic activity and poorer cognitive performance than healthy controls, with the greatest impairment seen in non-paroxysmal AF. In patients who underwent catheter ablation, glymphatic activity improved after sinus rhythm was restored, suggesting a possible link between heart rhythm, brain waste clearance, and cognition.

30 Mar 2026