Lymph Node News and Research

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Lymph is clear or white fluid that travels through vessels, moves within tissues and work to keep all the parts of the body clean. After passing through the channels of the lymphatic system they drain into the lymph nodes. The lymph nodes act as filters along the lymphatic system. These nodes trap germs like bacteria, viruses, toxins as well as cancer cells and ensure that these are removed from the body.

Researchers use PET tracer to identify ER expression differences in metastatic breast cancer patients

In metastatic breast cancer, prognosis and treatment is largely influenced by estrogen receptor expression of the metastases.

7 Aug 2018

Patients with colon cancers on the right side have worse survival rates than those with left-sided tumors

Patients with colorectal cancer tumors on the right side may have poorer five-year survival rates than those whose tumors are located on the left side.

24 Jul 2018

Researchers shed light on risks presented by residual disease for younger breast cancer patients

A new study from the Stanford Cancer Institute finds that young women who are treated with chemotherapy for breast cancer but have residual tumor in either the breast or lymph nodes have higher chances of recurrence compared to those with no evidence of any residual invasive tumor (pathologic complete response).

23 Jul 2018

Homogenous BTK occupancy assay used in tirabrutinib clinical studies

In a new SLAS Discovery article, Helen Yu and a team of researchers at Gilead Sciences, Inc. present a time-resolved fluorescence resonance energy transfer-based Bruton's tyrosine kinase occupancy assay that can measure target engagement in peripheral blood mononuclear cells and in lymph-node and bone-marrow samples.

17 Jul 2018

Researchers develop spider silk microcapsules that can deliver vaccine directly to immune cells

To fight cancer, researchers increasingly use vaccines that stimulate the immune system to identify and destroy tumor cells.

12 Jun 2018

Biotheranostics presents key data for CancerTYPE ID and Breast Cancer Index at ASCO 2018

Biotheranostics, Inc. announces new data from studies for both of its proprietary molecular diagnostic tests, CancerTYPE ID and Breast Cancer Index to be presented on Saturday, June 2nd and Monday, June 4th at the annual meeting of the American Society of Clinical Oncology in Chicago.

8 Jun 2018

Understanding cancer heterogeneity may help avoid harmful effects of chemotherapy

"Understanding cancer heterogeneity could further reduce chemo use," says cancer research expert Antonio Giordano, MD, PhD, Director of the Sbarro Institute for Cancer Research and Molecular Medicine at Temple University. "Further study of cases that can successfully be treated with hormone- and immunotherapy, and how to identify them, will unlock this potential."

7 Jun 2018

New minimally invasive procedure shortens hospital stay for melanoma patients

Lisa Chappell enjoys the summer sun, spending time outside and relaxing on the Coosa River at her Gadsden residence. Now, after being diagnosed with melanoma in 2015, she is much more cautious about her outdoor habits.

31 May 2018

Agendia and Angsana partner to market MammaPrint, BluePrint breast cancer tests in Southeast Asia

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, and Angsana Molecular & Diagnostics Laboratory Pte Ltd, a subsidiary of Parkway Pantai, announce a partnership to market the MammaPrint Breast Cancer Risk of Recurrence test and the BluePrint Molecular Subtyping test to physicians across Southeast Asia, including Singapore, Malaysia, Vietnam, Brunei and Myanmar.

31 May 2018

Analysis of lymph node dissection shows no overall survival benefit in renal carcinoma patients

An analysis of lymph node dissection in renal cell carcinoma that has not spread to other organs indicates the procedure is often performed for stage 1 disease and shows no overall survival benefit.

21 May 2018

New data supports clinical use of DecisionDx-Melanoma test to inform SLNB options

Castle Biosciences, Inc., the skin cancer diagnostics company providing molecular diagnostics to improve cancer treatment decisions, today announced the presentation of data supporting clinical use of the DecisionDx®-Melanoma test to inform sentinel lymph node biopsy (SLNB) recommendations.

7 May 2018

Lymph node status after preoperative therapy determines survival of esophageal cancer patients

According to a new study, the status of lymph nodes rather than the status of the primary tumor following preoperative neoadjuvant chemotherapy or chemoradiation therapy is the most important factor that determines whether patients with locally advanced esophageal cancer will survive.

2 May 2018

Direct contact with lymphatic endothelial cells promotes melanoma metastasis

Despite the declining death rates for many individual cancer types, mortality for a few cancers has stabilized or even increased. One of these is melanoma due to its ability, in later stages, to spread to other parts of the body.

2 May 2018

Novel magnetic nanoparticles move from lab to first breast cancer clinical trials

Sandia National Laboratories materials chemist Dale Huber has been working on the challenge of making iron-based nanoparticles the exact same size for 15 years.

30 Apr 2018

Axillary ultrasound imaging found to be inferior for detecting lymph node metastases in breast cancer

For patients diagnosed with breast cancer, determining whether cancer cells have spread to the axillary lymph nodes of the armpit is important for guiding treatment decisions. It has been debated whether axillary ultrasound imaging is equally sensitive for detecting axillary metastatic lymph nodes in different subtypes of breast cancer.

17 Apr 2018

New 'lymphoma micro-reactor' device targets chemo-resistant tumors

Non-Hodgkin lymphoma, a cancer that is diagnosed in the U.S. more than 70,000 times annually, arises from overly proliferating immune cells within the body's lymph nodes, which are connected to a network of lymph vessels through which lymphatic fluid flows.

12 Apr 2018

Mice study reveals important role of pTreg cell population in autoimmune diabetes

In autoimmune diseases such as type 1 diabetes, some of the immune system's T cells mistakenly attack the body's own cells, while protective T regulatory cells try to defend against that attack.

6 Apr 2018

Researchers discover Tfh cell dysfunction in HIV-infected patients

A team of chemical and biomedical engineers from the Cockrell School of Engineering at The University of Texas at Austin, in collaboration with researchers from the University of Pennsylvania, have discovered that HIV-infected patients experience a dysfunction in a certain type of immune cell: the follicular helper T (Tfh) cell.

6 Apr 2018

Research finds breast lesions in transmen undergoing mastectomy

The number of transmen seeking gender-confirming surgery has risen in the past decade. In a paper published in the British Journal of Surgery analyzing breast tissue from 344 transmen undergoing mastectomy, breast lesions--either benign or malignant--were present in 166 individuals (48.3%).

5 Apr 2018

Sentinel lymph node biopsies could be safely avoided for some breast cancer patients

Sentinel lymph node biopsies, where lymph nodes are surgically removed to check for signs of breast cancer spread, could be safely avoided for some women, according to research presented at the 11th European Breast Cancer Conference.

21 Mar 2018